The Byki complex on the left bank of the Seim River (Desna basin) comprises eight sites, including multilayer ones, differing chronologically and culturally. The dates of key cultural layers are from 21 to 18 thousand BP. Questioning the use of local landscapes by prehistoric people and the reasons for repeated occupation of the area required a paleolandscape reconstruction. For this purpose, a set of methods were applied on a research scale from local (archaeological excavation) to regional (within a radius of several kilometres). The site's position in the regional topography has been studied using GIS methods, for the nearest encirclement of Byki a detailed digital terrain model was constructed. The near-surface stratigraphy was studied by ground penetrating radar (GPR) and magnetic survey, coring and archaeological excavations. This resulted in the creation of a map of natural depressions layout and their three-dimensional visualisation. It was found that by the time people first arrived, the natural relief was a combination of sand dunes and rounded thermokarst sinkholes. The sediments filling the sinkholes indicate the over-watered conditions made them unsuitable for human habitation (the cultural layers do not extend into the sinkholes), but they could provide a source of water. Most of the sites are found on top of an aeolian barkhan. The distance maps showed that the sites’ location provided the best visibility in all directions. Thus, this atypical location of Byki sites at significant distances from the nearest rivers can be explained by a combination of several advantages: location on the edge of a valley in terms of distance vision, local topographic diversity that provided comfortable living conditions and possibly a water supply.