From the geomorphological cartography, the geometric and spatial distribution of the quaternary forms and deposits are analyzed, with special relevance to the fluvial terraces that allow obtaining the chronology of the successive landscape changes of the course of the Tagus River attributed to the activity of the Fault of Alentejo-Plasencia (APF). The “Appalachian” relief of Monfragüe National Park, constituting a series of quartzitic combs with direction NW, between which they find slopes, hills and valleys following the same direction, for the dismantlement of the Cenozoic cover that was covering the substratum (still present in the central sector) and encasement of the Rivers Tagus and Tiétar. The remains of fluvial terraces inside and outside the Park stand out at different heights and so they originate from different times and show different landscapes along the routes of the Tagus river and its movement over time. In the north end (basin of the Campo Arañuelo), there are remains of ten fluvial terraces of relative importance attributed to the River Tagus (with heights relative to the thalweg between 120 and 20 m). In the south edge, there are eight levels attributed to a former fluvial drainage network, which assimilates to the River Tagus, with the more recent level reaching over 280 m on the current river. Neotectonics readjustments that rejuvenated the relief produced the elevation of the socle and cover, at the time of diversions in the path of the fluvial network, up to the structure and encasement (for supertax and/or antecedence). During the Quaternary, the activity of the Alentejo-Plasencia Fault (APF) has given rise to palaeogeographic changes in the fluvial valley of the Tagus River. During the ancient Lower Pleistocene, its course passed south of the current one (Talaván-Torrejón el Rubio basin); at the end of the Lower Pleistocene, it came out crossing the syncline through the Boquerón porthole, and the meander that bordered the town of Almaraz was abandoned; at the beginning of the Middle Pleistocene, it changes its direction, from NE–SW to SE–NW, leaving the porthole and joining the Tiétar river within the Park; later it moves somewhat to the south. These changes in the route and the anomalous fitting of the course of the Tagus River into the Paleozoic substrate, have been attributed to the APF, which, through impulses, has had a great activity from the Lower Pleistocene to the Middle Pleistocene.