Candidate Pairs Research Articles

Heterogeneous Energy-aware Load Balancing for Industry 4.0 and IoT Environments

With the improvement of global infrastructure, Cyber-Physical Systems (CPS) have become an important component of Industry 4.0. Both the application as well as the machine work together to improve the task of interdependencies. Machine learning methods in CPS require the monitoring of computational algorithms, including adopting optimizations, fine-tuning cyber systems, improving resource utilization, as well as reducing vulnerability and also computation time. By leveraging the tremendous parallelism provided by General-Purpose Graphics Processing Units (GPGPU) as well as OpenCL, it is possible to dramatically reduce the execution time of data-parallel programs. However, when running an application with tiny amounts of data on a GPU, GPU resources are wasted because the program may not be able to fully utilize the GPU cores. This is because there is no mechanism for kernels to share a GPU due to the lack of OS support for GPUs. Optimal device selection is required to reduce the high power of the GPU. In this paper, we propose an energy reduction method for heterogeneous clustering. This study focuses on load balancing; resource-aware processor selection based on machine learning is performed using code features. The proposed method identifies energy-efficient kernel candidates (from the employment pool). Then, it selects a pair of kernel candidates from all possibilities that lead to a reduction in both energy consumption as well as execution time. Experimental results show that the proposed kernel approach reduces execution time by 2.23 times compared to a baseline scheduling system. Experiments have also shown that the execution time is 1.2 times faster than state-of-the-art approaches.

MEDIA SOSIAL SEBAGAI SARANA KOMUNIKASI KANDIDAT PADA PEMILIHAN KEPALA DAERAH DI KOTA MAKASSAR TAHUN 2020

This study aims to explain the use of social media by candidates for Mayor in the Election of Mayor and Deputy Mayor of Makassar in 2020. This study uses a qualitative content analysis method. The results of the study show that the campaign efforts carried out by candidates for Mayor and Deputy Mayor of Makassar are through social media with content related to candidate pairs, program delivery, and visits using the help of influencers. In addition, content delivery is also carried out using hashtags on Instagram and using podcasts that are shared on the Instagram accounts of each candidate pair. This effort is quite influential in influencing the choices of millennials in Makassar City because the content presented is packaged innovatively so that the delivery of political messages can influence novice voters in Makassar City.

Satya Hredaya in Accountability of Election Campaign Funds for 2018 Bali Regional Head

The concept of accountability is part of the concept of good corporate governance which includes accountability, transparency, independence, and objectivity. The form of accountability (accountability) for the financial management of pairs of candidates for the regional head election (pilkada) is the submission of campaign finance reports to the provincial/district KPU, audited by public accountants and open to public access. One of the foundations that must be adhered to in accordance with the accountability of reports related to the campaign is Satya Hrdaya. Satya Hradaya means that a leader must be honest with himself or loyal in his heart. Based on this phenomenon, this article discusses the accountability of the 2018 Bali regional head election campaign fund reports (pilkada) in the perspective of Tri Hita Karana. This study uses a qualitative-analytic method with an ethnomethodological approach. The results obtained are as follows: the implementation of spiritual, economic, social and ecological accountability from the Koster-Ace campaign finance report is reflected in the character of the leader who holds the values ​​of truth, morality, science, and is ready to serve the country. According to Satya Hredaya's teachings, sometimes humans often ignore the deepest whispers of the heart.

Exploring synthetic lethal network for the precision treatment of clear cell renal cell carcinoma

The emerging targeted therapies have revolutionized the treatment of advanced clear cell renal cell carcinoma (ccRCC) over the past 15 years. Nevertheless, lack of personalized treatment limits the development of effective clinical guidelines and improvement of patient prognosis. In this study, large-scale genomic profiles from ccRCC cohorts were explored for integrative analysis. A credible method was developed to identify synthetic lethality (SL) pairs and a list of 72 candidate pairs was determined, which might be utilized to selectively eliminate tumors with genetic aberrations using SL partners of specific mutations. Further analysis identified BRD4 and PRKDC as novel medical targets for patients with BAP1 mutations. After mapping these target genes to the comprehensive drug datasets, two agents (BI-2536 and PI-103) were found to have considerable therapeutic potentials in the BAP1 mutant tumors. Overall, our findings provided insight into the overview of ccRCC mutation patterns and offered novel opportunities for improving individualized cancer treatment.

Performance of The Election Supervisory Agency in The Implementation of The 2020 Surakarta City Election

This research departs from the indications of violations found in regional head elections, such as campaigns that are not in accordance with the rules of the General Election Commission (KPU) and the State Civil Apparatus (ASN) who favor one pair of candidates and vote counting, illegal voter registration, intimidation against voters who are contrary to the spirit of the Election Law or not in accordance with democratic principles. In this case, the performance of the Election Supervisory Body (Bawaslu) of Surakarta City in carrying out its duties and authorities. This research is descriptive with a qualitative approach, namely the researcher tries to describe and reveal all phenomena, symptoms, events as they are in the form of descriptions. The prevention carried out by Bawaslu also involves the general public in the form of participatory supervision. However, if there is a violation during the campaign, Bawaslu can only reprimand it. Because the rules in the General Election Commission Regulation (PKPU) regarding prohibitions that must be avoided. Law Number 32 of 2004 which states that regional heads and deputy regional heads are elected in one pair of candidates which is carried out democratically based on the principles of direct, general, free, confidential, honest and fair.

Religious issues as a message in political communications during local elections

This research focuses on religious issues used as messages in political communication. A campaign is a form of political communication by one of the candidates for local leader dan vice local leader of Gresik regency Sambari Qosim (SQ) in the 2015 regional election. This study employed a qualitative approach; therefore, the researcher used observation, in-depth interviews, and documentation to collect data. The study found that the SQ candidate pair used religious issues as a message in their political campaign because the local vice leader of Gersik Regency, Mohammad Qosim, was the son of a Kyai. Thus, such a strategy made it easier for him to gain sympathy from the voters, who would ultimately determine his choice of the pair. This strategy was implemented due to the socio-cultural community of Gresik Regency, a religious society that considers religion to be sacred, including the figure of a Kyai. As a religious figure, the Kyai must be obeyed and become an example in attitude and behaviour. This condition prompted the SQ candidate to take advantage of religious issues to gain as many votes as possible to win the 2015 regional elections.

Searching for giant planets in the outer Solar system with far-infrared all-sky surveys

ABSTRACT We have explored a method for finding giant planets in the outer Solar system by detecting their thermal emission and proper motion between two far-infrared all-sky surveys separated by 23.4 yr, taken with the InfraRed Astronomical Satellite (IRAS) and the AKARI Space Telescope. An upper distance limit of about 8000 AU is given by both the sensitivities of these surveys and the distance at which proper motion becomes too small to be detected. This paper covers the region from 8000 AU to 700 AU. We have used a series of filtering and SED-fitting algorithms to find candidate pairs, whose IRAS and AKARI flux measurements could together plausibly be fitted by a Planck thermal distribution for a likely planetary temperature. Theoretical studies have placed various constraints on the likely existence of unknown planets in the outer Solar system. The main observational constraint to date comes from a WISE study: an upper limit on an unknown planet’s mass out into the Oort cloud. Our work confirms this result for our distance range, and provides additional observational constraints for lower distances and planetary masses, subject to the proviso that the planet is not confused with Galactic cirrus. We found 535 potential candidates with reasonable spectral energy distribution (SED) fits. Most would have masses close to or below that of Neptune (∼0.05 Jupiter mass), and be located below 1000 AU. However, examination of the infrared images of these candidates suggests that none is sufficiently compelling to warrant follow-up, since all are located inside or close to cirrus clouds, which are most likely the source of the far-infrared flux.

Overcoming selection bias in synthetic lethality prediction.

MotivationSynthetic lethality (SL) between two genes occurs when simultaneous loss of function leads to cell death. This holds great promise for developing anti-cancer therapeutics that target synthetic lethal pairs of endogenously disrupted genes. Identifying novel SL relationships through exhaustive experimental screens is challenging, due to the vast number of candidate pairs. Computational SL prediction is therefore sought to identify promising SL gene pairs for further experimentation. However, current SL prediction methods lack consideration for generalizability in the presence of selection bias in SL data.ResultsWe show that SL data exhibit considerable gene selection bias. Our experiments designed to assess the robustness of SL prediction reveal that models driven by the topology of known SL interactions (e.g. graph, matrix factorization) are especially sensitive to selection bias. We introduce selection bias-resilient synthetic lethality (SBSL) prediction using regularized logistic regression or random forests. Each gene pair is described by 27 molecular features derived from cancer cell line, cancer patient tissue and healthy donor tissue samples. SBSL models are built and tested using approximately 8000 experimentally derived SL pairs across breast, colon, lung and ovarian cancers. Compared to other SL prediction methods, SBSL showed higher predictive performance, better generalizability and robustness to selection bias. Gene dependency, quantifying the essentiality of a gene for cell survival, contributed most to SBSL predictions. Random forests were superior to linear models in the absence of dependency features, highlighting the relevance of mutual exclusivity of somatic mutations, co-expression in healthy tissue and differential expression in tumour samples.Availability and implementation https://github.com/joanagoncalveslab/sbsl Supplementary information Supplementary data are available at Bioinformatics online.

KOMUNIKASI POLITIK ANIES BASWEDAN DALAM MEMBENTUK OPINI PUBLIK MELALUI MEDIA SOSIAL MENJELANG PEMILIHAN PRESIDEN 2024

Political communication is a crucial element that must exist among political actors because political communication can build the image of political actors in the eyes of society. Moreover, the presidential election in Indonesia will take place in about two years. Various issues regarding who will become the candidate pair in the 2024 Presidential Election have been frequently discussed by the media and the public. Various names of political figures are predicted to run for office in 2024. Various responses and public opinion regarding political actors also varied. Some voluntarily supported and some even openly disapproved of the issue of the intended political actor nominating himself in the 2024 presidential election. One example of such a political actor is Anies Baswedan. Anies himself is an example of a political actor who often uses social media to convey his political communications. Social media was chosen because it is the most accessible platform for two-way communication. Therefore, here we will analyze Anies Baswedan's style of political communication on social media and public opinion given by the public.

PRAKTIK POLITIK UANG DI KOTA SERANG PROVINSI BANTEN

The Regional Head Election (Pilkada) of Serang City in 2018 is the third batch of simultaneous local elections held simultaneously throughout Indonesia. The problems of the 2018 Regional Head Elections in Serang City, leaving various obstacles and weaknesses. One of them is related to the phenomenon of money politics. The focus of this research examines the monitoring of money politics practices in the 2018 regional elections in Serang City. The results of this study attempt to describe the supervision of money politics in Serang City in the 2018 regional elections by the Serang City Supervisory Committee (Bawaslu) which found that there were money politics practices carried out by sympathizers of the candidate pair team. The research method in this study uses a qualitative method approach

UNSUR SEMANTIK DEBAT PUBLIK PASANGAN CALON PADA PILGUB JATIM 2018: KAJIAN ANALISIS WACANA KRITIS [Semantic Elements of the Candidate Pair’s Public Debate in the 2018 East Java Governor Election A Study of Critical Discourse Analysis (CDA)

The title of this article is "Semantic Elements / Meaning of the Words of the Public Debate of Candidate Pairs in the 2018 East Java Gubernatorial Election in conveying the East Java development program for the Next Five Years: A Study of Critical Discourse Analysis (AWK)." The issue raised is how the semantic element/meaning of the word public debate of the candidate pairs in the 2018 East Java Pilgub in conveying the East Java development program for the next five years: Critical Discourse Analysis (AWK). The objectives of this study are: to describe, interpret, and explain the semantic elements/meaning of words used by the candidate pairs in the 2018 gubernatorial election in conveying the East Java development program for the next five years. The theories used are public debate, campaign language, pilkada, and critical discourse analysis/awk: public debate, campaign, ideology, election, and critical discourse analysis/AWK. The research method used is the qualitative method. The results showed that the semantic elements/meaning of words (1) experience value: (a) ideologically fought words, (b) presented metaphors, (2) relational values: (a) euphemistic expressions, (b) choice of words formal, and (3) expressive value: (a) words that express positive evaluations, (b) words that express negative evaluations.

The shaping of cancer genomes with the regional impact of mutation processes

Mutation signature analysis has been used to infer the contributions of various DNA mutagenic-repair events in individual cancer genomes. Here, we build a statistical framework using a multinomial distribution to assign individual mutations to their cognate mutation signatures. We applied it to 47 million somatic mutations in 1925 publicly available cancer genomes to obtain a mutation signature map at the resolution of individual somatic mutations. Based on mutation signature-level genetic-epigenetic correlative analyses, mutations with transcriptional and replicative strand asymmetries show different enrichment patterns across genomes, and “transcribed” chromatin states and gene boundaries are particularly vulnerable to transcription-coupled repair activities. While causative processes of cancer-driving mutations can be diverse, as shown for converging effects of multiple mutational processes on TP53 mutations, the substantial fraction of recurrently mutated amino acids points to specific mutational processes, e.g., age-related C-to-T transition for KRAS p.G12 mutations. Our investigation of evolutionary trajectories with respect to mutation signatures further revealed that candidate pairs of early- vs. late-operative mutation processes in cancer genomes represent evolutionary dynamics of multiple mutational processes in the shaping of cancer genomes. We also observed that the local mutation clusters of kataegis often include mutations arising from multiple mutational processes, suggestive of a locally synchronous impact of multiple mutational processes on cancer genomes. Taken together, our examination of the genome-wide landscape of mutation signatures at the resolution of individual somatic mutations shows the spatially and temporally distinct mutagenesis-repair-replication histories of various mutational processes and their effects on shaping cancer genomes.

Penerapan Asas Pemilu Terhadap Electronic Voting (E-Voting) Pada Pemilu Tahun 2024

This study aims to determine the implementation of the E-voting electoral system (Electronic Voting) which is a new method in general elections in Indonesia, the use of the E-voting system (Electronic Voting) later in the 2024 election is a step forward to realize the election principle, namely Luber Jurdil. The use of the conventional system in the previous election was still considered ineffective and in the end gave birth to various problems such as the inaccuracy of the vote count results, it was suspected that there were voters who chose more than one pair of candidates, took a long time to determine the results of the general election, used a lot of human resources. So from these problems, a new system is needed to be able to maximize the electoral system so that the Luber Jurdil principles are implemented. The research method used in this research is normative juridical by using a statutory approach and a conceptual approach to a legal issue that is currently relevant. And is prescriptive. The results of the study conclude that the E-voting system in general elections is a system that is more effectively used and has fulfilled the election principle, namely Luber Jurdil, so that in the implementation of E-voting a special and explicit regulation can be formed, both in the form of laws and regulations. Perpu. So that later in the implementation it has regulations and legitimacy that are binding and clear in accordance with Pancasila and the 1945 Constitution

Pengaruh Media Sosial Sebagai Sumber Pengetahuan Politik Generasi Z Terhadap Literasi Politik Pada Pemilu 2020

Pilkada is a process of implementing democracy that is followed by all circles of society, including generation Z. Social Media is very closely related to Generation Z. Generation Z tends to master technology and the internet since childhood. In the implementation of the 2020 Pilkada. Therefore, it is necessary to study the influence of social media as a source of political knowledge on political literacy in the 2020 Election of Blora Regency in the era of the covid-19 pandemic. This study aims to determine how influential social media is as a source of political knowledge in political literacy generation Z. This study was designed using mixed methods with a sequential explanatory strategy with data collection and quantitative data analysis in the first stage, followed by qualitative data collection and analysis. The sample in this study is Generation Z aged 17-24 years in Blora Regency, who have used their voting rights in the 2020 Pilkada. This study indicates that generation Z's political knowledge, knowledge of government, and knowledge of the environment and society are considered sufficient for political literacy. Because it is in the 2,3-3.6 interval, knowledge related to the political game rules is considered suitable for political literacy because it is at the highest interval of 3.6-4.9. From the output, the R square of political knowledge has a value of 0.641, which means that 64.1% of generation Z's political knowledge affects political literacy. Social media as a source of political knowledge affects the level of political literacy of generation Z. Other factors that can influence the political knowledge of generation Z are age, education, sources of information, experience, and occupation. However, social media as a source of political knowledge has not been appropriately utilized by the organizers and the candidate pair in providing information to voters.

Dampak Pembatasan Kampanye Bagi Pemilih Pemula dalam Mendapatkan Informasi Kepemiluan di Masa Pandemi

The purpose of this study was to analyze the impact of campaign restrictions for novice voters to obtain electoral information in the 2020 local elections in the midst of the covid-19 pandemic. The research method uses descriptive qualitative research. There are 21 research informants taken from representatives of BEM administrators throughout Bengkulu city, in selecting informants using purposive sampling technique, data obtained through interviews and documentation. The results of the study show a) In limited meetings, one of which is the lack of political education in the community; b) Regarding the rights and disclosure of information, namely: millennial voters are involved in the socialization process, through social media; c) Regarding voter participation, there are assumptions of millennial voters who are still apathetic towards the candidate pair and have an impact on the political confidence of millennial voters. The conclusion of this research is that campaign restrictions will cause limitations in obtaining information about election organizers, election participants, voters and even information about the vision, mission and work program plans offered by pairs of candidates for Pilkada candidates.
 
 Keywords: Election Campaign, Election Information, Novice Voters, Pandemic. 

Relasi Birokrat dan Politisi Dalam Pilkada Gubernur Sumatera Barat Tahun 2020

In electoral politics, the relationship between bureaucrats and politicians is increasingly obvious because the interests between the two meets at one point, namely power. As a result, ASN, which should be neutral in elections and elections, is drawn into the vortex of political currents, especially in the implementation of the Pilkada which is in direct contact with the interests of the bureaucrats and ASN. This phenomenon occurs in almost all of Indonesia during the Pilkada, especially since the candidate who is advancing is the incumbent candidate. This practice also occurred in the 2020 West Sumatra gubernatorial election. Bureaucrats became one of the supporters and loyalists (brokers) of the candidates who came forward. One of the pairs of candidates who have a lot of contact with these bureaucrats is the pair Mahyeldi-Audy. One of them is the appointment of three Padang City Government officials to become officials in the West Sumatra Provincial Government, although they have gone through the screening process, there are still allegations of remuneration for the contributions of the three bureaucrats in winning Mahyeldi-Audy. To analyze the problems above, the method used is a qualitative approach and the type of research used is a literature review. In this study, it is explained that in the process of selecting the governor, bureaucrats and PKS collaborate in collecting votes according to their respective duties. This collaboration was one of the decisive factors for Mahyeldi and PKS's victory in the West Sumatra gubernatorial election. the practice of political brokers and pig-barrel politics explains the relationship between bureaucrats and politicians. Bureaucrats who have a strong social network engine are able to get votes in their respective environments, especially those senior bureaucrats are community leaders who have supporters. Coupled with pragmatic politics that prioritizes money politics in elections, making these bureaucrats and politicians a force in the winning process.

Pelaksanaan Kampanye Pemilihan Gubernur Sumatera Barat Berdasarkan PKPU Nomor 13 Tahun 2020

This study aims to determine the implementation of the West Sumatra Governor Election Campaign based on PKPU Number 13 of 2020. The existence of the Covid-19 pandemic makes the 2020 Campaign Implementation must comply with the health protocols as stipulated in PKPU Number 13 of 2020. The type of research is qualitative research with descriptive methods. Informants were selected using a purposive sampling technique, namely the selection of informants based on certain characteristics according to the research objectives. Data collection is carried out by interviewing related to the problems studied, then documentation studies which are supporting data and relevant to the problems studied in the form of reports, legislation, pictures and other supporting data. The technique of testing the validity of the data uses the triangulation method. While the data analysis technique is done by reducing the data, presenting the data, and drawing conclusions. The results showed that the Implementation of the 2020 West Sumatra Governor Election Campaign had been carried out in accordance with the rules contained in PKPU Number 13 of 2020 although there were still violations committed by the 2020 West Sumatra Governor Candidate Pair. And the factors that influenced the campaign were the campaigners, campaign messages, campaign media, and campaign target audiences

Kampanye Politik Kampanye Politik Pilkada Pasangan Calon Wali Kota Tangerang Selatan Siti Nur Azizah-Ruhamaben

The purpose of this research was specifically to determine the political campaign of the candidate pair for Mayor Election of South Tangerang (Tangsel), Siti Nur Azizah-Ruhamaben during the Covid-19 pandemic. The 2020 Mayor Election was like a war between dynasties, because of the candidates have a political power based on their families. The candidate of H. Muhamad and Rahayu Saraswati Djojohadikusumo have a connection with the Minister of Defense, Prabowo Subianto which was her uncle . While the other candidates, Siti Nur Azizah was the daughter of Vice President Ma'ruf Amin. Meanwhile the another one, Pilar Saga Ichsan, was the son of the Regent of Serang, Ratu Tatu which was the younger sister of the former Banten Governor, Ratu Atut Chosiyah. The author used a qualitative research method with a descriptive approach. The results of this research were the political campaign of Siti Nur Azizah-Ruhamaben in the 2020 Mayor Election still focuses on offline campaigns. Procurement of props or outdoor media and greeting residents directly (including blusukan). Azizah-Ruhamaben also intensifies campaigns virtually or digitally, such as through social media or other digital applications such as WhatsAap groups and also creates and intensively campaigns on webs and Blogspot, and conducts character friendships through zoom meetings. In addition, Azizah–Ruhamaben integrated the two campaigns, one of which was by carrying out a drive-in declaration. The drive-in declaration has become a new innovation related to campaigns during the pandemic. Keywords: Campaign, Pilkada, Politic

KUASA ETNISITAS DALAM MEREK POLITIK KONSUMEN KABUPATEN TEBO DI ERA REFORMASI

This study will examine political marketing in the electoral contestation in Tebo Regency during the Reformation Era which is then associated with the construction of the ethnicity of the people of Tebo Regency as the main force in winning the power contest. This study aims to determine the construction of political marketing on the electoral political contestation targeting populism of ethnicity in Tebo Regency. By using descriptive qualitative research methods, the results of this study answer that the real power of ethnicity is able to become a consumer political brand through political marketing carried out by candidate pairs who fight with a combination pattern of ethnicity (Javanese and Jambi Malay). Then there is a distributive populist policy that targets ethnic groups that are the basis of voters with the aim of personal political interests to be re-elected in the election. This study offers a recommendation that in the context of ethnicity, which is usually one of the topics in the theory of voting behavior, it is also packaged in a political marketing strategy which can cause several negative impacts later which causes the development process to not prioritize the principle of justice, resulting in polarization in society.

Loop Closure Detection With Reweighting NetVLAD and Local Motion and Structure Consensus

Dear Editor, Loop closure detection (LCD) is an important module in simultaneous localization and mapping (SLAM). In this letter, we address the LCD task from the semantic aspect to the geometric one. To this end, a network termed as AttentionNetVLAD which can simultaneously extract global and local features is proposed. It leverages attentive selection for local features, coupling with reweighting the soft assignment in NetVLAD via the attention map for global features. Given a query image, candidate frames are first identified coarsely by retrieving similar global features in the database via hierarchical navigable small world (HNSW). As global features mainly summarize the semantic information of images and lead to compact representation, information about spatial arrangement of visual elements is lost. To provide fine results, we further propose a feature matching method termed as local motion and structure consensus (LMSC) to conduct geometric verification between candidate pairs. It constructs local neighborhood structures of local features through motion consistency and manifold representation, and formulates the matching problem into an optimization model, enabling linearithmic time complexity via a closed-form solution. Experiments on several public datasets demonstrate that LMSC performs well in feature matching, and the proposed LCD system can yield satisfying results.