Dysmenorrhea Research Articles

Pengaruh Aromaterapi Lavender Terhadap Penurunan Tingkat Nyeri Disminore Pada Siswi Kelas XII SMK Kesehatan Mulya Karya Husada Jagakarsa Tahun 2023

Dysminorrhea is pain caused by spasm of the uterine muscles and increased levels of prostaglandins. Pain before or during menstruation is characterized by one of the symptoms that women often experience during menstruation, namely pain in the lower abdomen. Lavender aromatherapy is an alternative treatment method using lavender fragrance containing linalyl acetate which has a relaxing effect on the nervous and muscle systems, while linalool has a relaxing and sedative effect so it is used to relieve menstrual cramps. This study aims to determine the effect of lavender aromatherapy on reducing the level of dysmenorrhea pain in class The data collection method uses the Numeric Rating Scale (NRS) menstrual pain measurement questionnaire. The population in this study was 89 respondents and the sample was 20 respondents. The results showed that the average level of pain in female students before being given lavender aromatherapy was moderate pain, after being given lavender aromatherapy showed a mild level of pain, and the pain level before and after being given lavender aromatherapy had a p-value of 0.000 (<0.05) using the Wilcoxon Signed Rank T-test which states that Ha is accepted and Ho is rejected, it can be concluded that there is an effect of lavender aromatherapy on reducing the level of dysmenorrhea pain in class XII female students at Mulya Husada Jagakarsa Health Vocational School in 2023.

Pengaruh Pemberian Jamu Temulawak (Curcuma Zanthorrhiza L) Terhadap Penurunan Nyeri Menstruasi Pada Remaja Putri di SMAN 1 Porehu Kabupaten Kolaka Utara

Temulawak herbal medicine is an alternative intervention in reducing the level of menstrual pain. Temulawak contains chemical compounds that have physiological activity. The curcumin content is also known as an anti-tumor, antioxidant, and pain reducer. The research aims to determine the effect of administering ginger herbal medicine (Curcuma zanthorrhiza L) on reducing menstrual pain in adolescent girls at SMAN 1 Porehu, North Kolaka Regency. The type of research used was quasi-experimental using a one group pretest-posttest research design. The sample in this study was all 27 young women who experienced pain during menstruation. The research results showed that the scale of menstrual pain before administering ginger herbal medicine (Curcuma zanthorrhiza L) reduced menstrual pain in young women at SMAN 1 Porehu, North Kolaka district in the mild pain category was 1 (3.7%), the moderate pain category was 13 (48%). .1%) and the severe pain scale category was 13 (48.1%). However, after administering ginger herbal medicine (Curcuma zanthorrhiza L) the reduction in menstrual pain in adolescent girls at SMAN 1 Porehu, North Kolaka district experienced changes where menstrual pain in the painless category was 15 (55.5%), and in the mild pain category was 12 ( 44.4%),. The conclusion is that there is an effect of giving ginger herbal medicine (Curcuma zanthorrhiza L) on reducing menstrual pain in adolescent girls at SMAN 1 Porehu, North Kolaka Regency (p value of 0.000 < α 0.05).

Characteristics of Far-Infrared Ray Emitted from Functional Loess Bio-Balls and Its Effect on Improving Blood Flow.

XRD diffraction and IR absorption were investigated for raw loess powder and heat-treated loess powder. Raw loess retains its useful minerals, but loses their beneficial properties when calcined at 850 °C and 1050 °C. To utilize the useful minerals, loess balls were made using a low-temperature wet-drying method. The radiant energy and transmittance were measured for the loess balls. Far-infrared ray (FIR) emitted from loess bio-balls is selectively absorbed as higher vibrational energy by water molecules. FIR can raise the body's core temperature, thereby improving blood flow through the body's thermoregulatory mechanism. In an exploratory study with 40 participants, when the set temperature of the loess ball mat was increased from 25 °C to 50 °C, blood flow increased by 39.01%, from 37.48 mL/min to 52.11 mL/min, in the left middle finger; in addition, it increased by 39.62%, from 37.15 mL/min to 51.87 mL/min, in the right middle finger. The FIR emitted from loess balls can be widely applied, in various forms, to diseases related to blood flow, such as cold hands and feet, diabetic foot, muscle pain, and menstrual pain.

“In our community, we normalize pain”: discussions around menstruation and uterine fibroids with Black women and Latinas

BackgroundUterine fibroids are non-cancerous neoplasms that arise from the uterus affecting over 75% of women. However, there is a disparity with Black women having an increased prevalence of nearly 80%. Black women also experience increased symptom burden, including younger age at the time of diagnosis and increased number and volume of fibroids. Less is known about other ethnoracially diverse women such as Latinas and the potential cultural impacts on fibroid burden and treatment.MethodsCommunity engagement studios were conducted to facilitate discussions with stakeholders on their uterine fibroid and menstruation experience. We recruited Black women (n = 6) diagnosed with uterine fibroids and Latinas (n = 7) without uterine fibroids. We held two virtual community engagement studios split by uterine fibroid diagnosis. The studios were not audio recorded and notes were taken by four notetakers. The notes were thematically analyzed in Atlas.ti using content analysis.ResultsParticipants felt there was a lack of discussion around menstruation overall, whether in the home or school settings. This lack of menstruation education was pronounced when participants had their first menstruation experience, with many unaware of what to expect. This silence around menstruation led to a normalization of painful menstruation symptoms. When it came to different treatment options for uterine fibroids, some women wanted to explore alternative treatments but were dismissed by their healthcare providers. Many participants advocated for having discussions with their healthcare provider about life goals to discuss different treatment options for their uterine fibroids.ConclusionDespite uterine fibroid diagnosis, there is silence around menstruation. Menstruation is a normal biological occurrence and needs to be discussed to help prevent delayed diagnosis of uterine fibroids and possibly other gynecological disorders. Along with increased discussions around menstruation, further discussion is needed between healthcare providers and uterine fibroid patients to explore appropriate treatment options.

Impact of government-issued financial incentive to medical facilities on management of secondary dysmenorrhea.

In April 2020, the Japanese government introduced a Specific Medical Fee for managing secondary dysmenorrhea (SD). This initiative provided financial incentives to medical facilities that provide appropriate management of SD with hormonal therapies. We aimed to assess how this policy affects the management processes and outcomes of patients with SD. Using a large Japanese administrative claims database, we identified outpatient visits of patients diagnosed with SD from April 2018 to March 2022. We used an interrupted time-series analysis and defined before April 2020 as the pre-introduction period and after April 2020 as the post-introduction period. Outcomes were the monthly proportions of outpatient visits due to SD and hormonal therapy among women in the database and the proportions of outpatient visits for hormonal therapy and continuous outpatient visits among patients with SD. We identified 815 477 outpatient visits of patients diagnosed with SD during the pre-introduction period and 920 183 outpatient visits during the post-introduction period. There were significant upward slope changes after the introduction of financial incentives in the outpatient visits due to SD (+0.29% yearly; 95% confidence interval, +0.20% to +0.38%) and hormonal therapies (+0.038% yearly; 95% confidence interval, +0.030% to +0.045%) among the women in the database. Similarly, a significant level change was observed after the introduction of continuous outpatient visits among patients with SD (+2.68% monthly; 95% confidence interval, +0.87% to +4.49%). Government-issued financial incentives were associated with an increase in the number of patients diagnosed with SD, hormonal therapies, and continuous outpatient visits.

Literature Review: Relationship of Lifestyle with Incidence of Primary Dysmenorrhea in College Students

Introduction: Menstruation is periodic and cyclic bleeding from the uterus, accompanied by endometrial desquamation. In specific individuals, menstruation can cause pain called dysmenorrhea, which is characterized by mild, moderate, and severe menstrual pain. Primary dysmenorrhea is not a life-threatening disorder, but it can hurt women's quality of life. Prevalence of menopause in Indonesia An estimated 55% of women of reproductive age experience pain during menstruation. Material and Methods: We searched articles published from 2014-2020 in PubMed, Proquest, and Google Scholar with the keywords "primary dysmenorrhea” AND “student lifestyle”. All data were gathered and analyzed. Results: The results showed that 8 articles showed the relationship between lifestyle and the occurrence of primary menstrual pain among female students. In comparison, the other two articles show that there is no relationship between lifestyle and primary dysmenorrhea in female students. Conclusion: This study concludes that an unhealthy lifestyle, such as high stress levels, infrequent exercise, and frequent consumption of fast food, is effective for primary dysmenorrhea during menstruation.

Systematic review on published studies on Matrabasti as an Ayurvedic intervention in Udavartini Yonivyapad (Primary Dysmenorrhea)

Objectives: Udavartini Yonivyapad (Primary Dysmenorrhea) a prevalent condition characterized by severe menstrual pain, has been addressed through various treatment modalities. This review aims to provide an updated perspective on the use of Matrabasti as an Ayurvedic intervention for Primary Dysmenorrhea. Methods: This study systematically reviewed thirteen published research studies on Matrabasti as an intervention for Udavartini Yonivyapad (Primary Dysmenorrhea), following PRISMA[3] guidelines. Searches were conducted on databases including Pubmed, Google Scholar, Cochrane library, DHARA, AYUSH Portal & Scopus, encompassing literature published in English language. A detailed analysis and exploration was made of the strengths, limitations, implications, and future research directions of the summarized studies. Results: These studies include 3 RCTs, 3 single group studies, and 7 single case studies with sample sizes varying from 50 to 10 participants. Treatment duration ranges from 7 to 9 days, starting mid-cycle or post-menstruation cessation, spanning 2 to 5 consecutive cycles. Some studies involve oral medication in conjunction with Matrabasti or alternative-day Ksheerabasti and Anuvasana/Sneha Basti. Assessment methods predominantly employ the visual analogue scale and multidimensional scoring. The review covered diverse formulations including Dashamoola Taila, Tila Taila, Phala Taila, Hingwadi Taila, Trivrutta Taila, Shatapushpa Taila, Sahacharadi Taila, Dhanwantaram Taila, Dashamoola Ksheerapaka and Mahanarayana Taila. Conclusion: Ayurvedic interventions, particularly Matrabasti formulations, present a diverse and promising avenue for managing Udavartini Yonivyapad (Primary Dysmenorrhea). The formulations, derived from classical Ayurvedic texts, showcase efficacy in balancing Vata Dosha, reducing pain severity and all associated symptoms, and improving overall well-being.

Clinical evaluation of Erand Tail Nabhi Puran in the management of Dysmenorrhea : Pilot Study

Dysmenorrhea is defined as painful menstrual cramps of uterine origin which can be correlated with Udavartini Yonivyapad. It is very common gynecological disorder in females specially in reproductive age. Sometimes it also hampers women’s daily routine. Udavarta Yonivyapad is explained in Ayurveda as a Nanatmaja Vata Vyadhi by Charaka where there is abnormal movement of Vayu in Pakwashay with painful menses. There are different types of NSAIDS, OC pills, painkillers, etc. to give temporary relief from pain but it also has side effects on body if taken in excess amount. In Ayurveda lot of formulations are used for treatment of same. An attempt has been made through Ayurveda classics in regards to dysmenorrhea with Nabhi Puran using Eranda Taila.

Understanding Adolescents' Experiences With Menstrual Pain to Inform the User-Centered Design of a Mindfulness-Based App: Mixed Methods Investigation Study.

Digital interventions are increasingly popular for the provision of nonpharmacological pain interventions, but few exist for adolescents with menstrual pain. User-centered design involves incorporating users across phases of digital health intervention design, development, and implementation and leads to improved user engagement and outcomes. A needs assessment is the first step of this approach. The goal of this study was to conduct a needs assessment to understand menstrual pain management needs and preferences and mindfulness experiences, preferences, and knowledge of adolescents with menstrual pain to inform the future development of an app for managing menstrual pain. We used an explanatory sequential mixed method design that included a survey followed by focus groups. Adolescents aged 13-17 years completed a survey (n=111) and participated in focus groups (n=16). Data were analyzed using descriptive statistics and thematic content analysis and synthesized to provide specific recommendations based on adolescent responses. Adolescents (n=111) who completed the survey reported a moderate understanding of mindfulness and menstrual pain. Over three-quarters (n=87, 78%) of participants practiced some form of mindfulness and 87% (n=97) of survey participants used nonpharmacological pain management strategies. Teens had a moderate perception that mindfulness could help their menstrual pain (mean 4.51/10, SD 2.45, with higher scores suggesting more interest). Themes were generated related to mindfulness experiences, menstrual pain knowledge and experiences, and app functionality. These themes underscored adolescents' need for continued support and flexible access to mindfulness activities; their awareness of multiple influences to pain, with potential for further education in this area; and the need for menstrual pain-specific content, along with content relevant to typical day-to-day experiences of adolescents. Adolescents with menstrual pain have an interest in using a mindfulness app for pain but have unique needs that need to be addressed to ensure app engagement and relevance for this population. Concrete recommendations for future app development are provided.

Vitamin D Supplementation for Patients with Dysmenorrhoea: A Meta-Analysis with Trial Sequential Analysis of Randomised Controlled Trials.

Vitamin D reduces prostaglandin levels and inflammation, making it a promising treatment option for dysmenorrhoea. However, its effects on pain intensity in different types of dysmenorrhoea remain unclear. We examined whether vitamin D supplementation decreases pain intensity in patients with dysmenorrhoea. The Cochrane Library, Embase, Google Scholar, Medline, and Scopus databases were searched from inception to 30 December 2023. Randomised controlled trials (RCTs) evaluating vitamin D supplementation effects on such patients were included. The primary and secondary outcomes were measured by the changes in pain intensity and rescue analgesic use, respectively. Pooled mean differences and rate ratios were calculated using a random-effect model; trial sequential analysis (TSA) was also performed. Overall, 11 studies involving 687 participants were included. Vitamin D supplementation significantly decreased pain intensity in patients with dysmenorrhoea compared with controls (pooled mean difference, -1.64; 95% confidence interval, -2.27 to -1.00; p < 0.001; CoE, moderate; I2 statistic, 79.43%) and indicated substantial heterogeneity among the included studies. TSA revealed that the current RCTs provide sufficient information. In subgroup analyses, vitamin D supplement reduced primary dysmenorrhoea pain but not secondary dysmenorrhoea pain. In conclusion, although substantial heterogeneity persists, vitamin D supplementation decreased pain intensity in patients with dysmenorrhea, especially in those with primary dysmenorrhoea.

Saffron extract as an emerging novel therapeutic option in reproduction and sexual health: recent advances and future prospectives.

Saffron, derived from Crocus sativus, is gaining research attention for potential therapeutic applications. Its diverse clinical applications extend to cardiovascular health, diabetes management, sleep quality, psychiatric illnesses, and rheumatoid arthritis. Saffron's positive effects on blood pressure, glucose levels, cognitive function, and inflammatory markers contribute to its versatility. Additionally, carotenoids like crocin and crocetin suggest anti-cancer potential. In terms of reproductive health, saffron's impact on male reproductive health shows conflicting findings on semen parameters. However, in female reproductive health, saffron appears promising for managing dysmenorrhoea, reducing menstrual pain, regulating hormonal fluctuations, and improving overall menstrual health. Safety considerations highlight the importance of adhering to specified dosages, as excessive intake may lead to toxicity. Yet, within the therapeutic range, saffron is considered safe, relieving symptoms without serious side effects, according to clinical research. Future trials in 2023 will explore saffron's potential in cancer therapy, diabetes management, mental health, stress response, cardiovascular health, postmenopausal women's well-being, and chronic obstructive pulmonary disease (COPD). This ongoing research underscores saffron's adaptability and promise as a natural treatment across various medical applications, emphasizing its efficacy. The current review, therefore, aims to provide up-to-date insights on saffron's role particularly in the realm of reproductive health, contributing to a growing body of evidence supporting its diverse therapeutic benefits.

Management of polycystic ovarian syndrome by Yoga basti and Mustadi ghanavati: An experience through Ayurvedic approaches

Polycystic Ovarian Syndrome (PCOS) is a prevalent and rapidly growing metabolic and endocrinological condition among women of reproductive age. Lifestyle factors such as sedentary habits, pollution, and excessive junk food consumption contribute to the escalating incidences of PCOS. Globally, it is estimated to affect 6%–10% of women, with a higher prevalence of 3.7% to 22.5% among Indian women. It is characterized by delayed menstruation, oligomenorrhea, acne, hirsutism, thinning of hair, infertility, and obesity. In Ayurveda, PCOS is not a direct term coined, but the conditions like Vandhya yoni vyapad (~primary infertility), Artava sroto vidhha lakshana (~symptoms due to vitiation of channels carrying menstrual blood), Nashtartava (~amenorrhoea), and Artava kshaya (~oligomenorrhea) as well as Pushpaghni jataharini (~clinical resemblance to PCOS) and Vikuta jataharini (~irregular menstrual and ovulatory cycle) may be strongly related to PCOS in terms of their characteristics. The presented case involves a 26-year-old female with irregular and painful menstruation, acne, hirsutism, and weight gain visited the outpatient department with a diagnosis of bilateral PCOS, confirmed through ultrasonography, revealing enlarged ovaries with a right ovary of volume 15 cc and a left ovary of volume 16 cc. After having a thorough examination, the patient underwent customized Ayurvedic treatment protocol, including oral medications, Yoga basti (~course of eight therapeutic enemas), dietary modifications, and practice of Suryanamaskara (~sun salutation). After three months, the patient reported symptomatic relief, and improved Quality of Life (QoL), as measured by the QoL-Short-Form-36 scale, and an ultrasound report without any abnormality. The observations infer that the Ayurvedic approaches are safe and effective in managing the conditions with hormonal imbalances like that of PCOS.

Primary dysmenorrhea: pathophysiology, improvement of diagnostic and treatment possibilities

Primary dysmenorrhea is one of the types of gynecological pathology, the frequency of which is 45-53% in girls and young women aged 13 to 45 years, which is not given enough attention in diagnosis and treatment.The pathogenesis takes into account the increased secretion of prostaglandins F2α and E2 in the period from the beginning of pregnancy to birth, which cause pelvic pain.The diagnosis is based on the patient's history, symptoms, examination, the treatment is aimed at improving the quality of life by prescribing nonsteroidal anti-inflammatory drugs, hormonal contraceptives and the use of non-medicinal means. Purpose: to specify some links in the pathogenesis of primary dysmenorrhea and, taking into account its multicomponent nature, to evaluate the effectiveness of the proposed treatment. Under observation there were 68 women who were divided into 2 groups: 34 women with primary dysme­norrhea (main group) and 34 healthy women (control group).The diagnosis of primary dysmenorrhea was established on the basis of complaints of patients about painful menstruation and accompanying symptoms during consultations with a gynecologist and endocrinologist.Treatment of patients in the main group was carried out with the drug, which includes Vitex agnus castus L, indinol-3-carbinol, 3,3-diindolyl-methane, extract of passionflower, California Eschscholzia. In women with typical symptoms, dysmenorrhea can be diagnosed on the basis of medical information without physical pelvic examination, empirical treatment should be initiated, including nonsteroidal anti-inflammatory drugs and/or oral contraceptives, because it is a functional condition resulting from an imbalance in the hormonal regulation of myometrial contraction. As a result of the proposed treatment, pain disappeared completely in 70% of patients (23/34), as well as vegetative-vascular (from 18 to 2% of patients), vegetative (from 10 to 1% of patients), metabolic and endocrine disorders (from 15 to 2% female patients), disorders of the emotional and mental sphere (from 25 to 10% of patients). Improvement in quality of life was noted by 80% (26/34) of patients, improvement in working capacity – by 70% (23/34) of patients, after 2 months – by 95% (31/34) and 85% (28/34), respectively, after 3 months all examined patients with primary dysmenorrhea noted an improvement in the quality of life and an increase in work capacity. Sexually active women with symptoms of inflammatory processes of the genital tract, severe dysmenorrhea should undergo pelvic examination. In view of safety and high therapeutic efficiency, the drug based on Vitex agnus castus can be offered for the treatment over the period lasting at least for3 months for girls and young women aged 13 to 45 years with primary dysmenorrhea.

Clinical experience of Tianxiong Granules in treatment of hypertension based on treatment principle of supressing Yang and promoting blood circulation

Hypertension is the most common chronic disease in clinics and has become the most common risk factor for cardiovascular diseases. Because of its high incidence rate, disability rate, and mortality, it has attracted worldwide attention. Despite continuous progress in modern medicine in the treatment of hypertension with new antihypertensive drugs such as Zilebesiran, a nucleic acid drug that acts on microRNA, direct renin inhibitors, and renal sympathetic blockade, the control rate is still not ideal. How to effectively prevent and control hypertension has become one of the urgent clinical challenges to be solved. Traditional Chinese medicine(TCM) has a long record of treating hypertension and has accumulated rich experience, including theoretical understanding, effective single medicine, compound medicine, traditional Chinese patent medicines, and classic famous prescriptions. In TCM, hypertension belongs to the categories of diseases such as dizziness and headache. Previous literature and clinical studies have found that hypertension has key pathogenesis such as fire syndrome, fluid syndrome, deficiency syndrome, and blood stasis syndrome. Among them, the hyperactivity of liver Yang is closely related to blood pressure fluctuations, blood pressure variability, inflammation, and sympathetic activity stimulation. Internal obstruction by blood stasis is closely related to the damage of target organs such as the heart, brain, and kidneys in hypertension. Therefore, the two key pathogenesis of liver yang hyperactivity and internal obstruction by blood stasis run through the entire process of hypertension. Previous studies have found that the effective empirical formula Tianxiong Granules, based on the principles of suppressing Yang and promoting blood circulation, originated from the classic formula Xiongqiong Tianma Pills in Yu Yao Yuan Fang. It is composed of Gastrodiae Rhizoma, Chuanxiong Rhizoma, Puerariae Lobatae Radix, Achyranthis Bidentatae Radix, and Cyathulae Radix and has significant therapeutic effects in the treatment of hypertension. The clinical indications include headache, dizziness, bloating, strong neck, and weak waist and legs. At the same time, it may be accompanied by poor speech, thirst, normal or loose stools, soreness in the waist and legs, lower limb pain, muscle and pulse spasm, menstrual and abdominal pain, dark red tongue, strong pulse strings, or straight and long pulse strings that pass through the mouth of an inch. In the combination rule, it can be used according to the different pathogenesis stages of hypertension patients. In the fire syndrome stage, it is often combined with Tianma Gouteng Decoction and Chaihu Jia Longgu Muli Decoction. In the fluid syndrome stage, it is often combined with Banxia Baizhu Tianma Decoction. In the deficiency syndrome stage, it is often combined with Liuwei Dihuang Pills and Shenqi Pills. In terms of dosage, it is important to focus on the main symptoms and adjust the dosage of key drugs based on blood pressure values. Some drugs can be used in sufficient quantities. By analyzing the compatibility of Tianxiong Granules, clinical application indications, combined formula experience, and dosage application experience, we provide effective treatment methods and more options for TCM to treat hypertension with Yang hyperactivity and blood stasis syndrome.

Management of Artavakshaya along with Dhatukshaya in lean adolescent girls: a narration

Abstract Background: Artavakshaya (~scanty menstruation/hypomenorrhea/oligomenorrhea) is one of the most prevalent reproductive disorders among adolescent girls now. Irregular, delayed and scanty menstruation, abdominal cramping, and lower back pain are the major symptoms of Artavakshaya. The condition can be correlated with oligomenorrhea along with hypomenorrhea based on similar symptomatology. Poor nutrition, stress, hormonal disturbance, and unhealthy lifestyle are the major causes of oligomenorrhea along with hypomenorrhea particularly in lean adolescent girls. Aim and Objective: This study aims to evaluate the efficacy of Ayurveda protocol in the management of Artavakshaya in adolescent girls. The rationale behind this study was only to prevent further gynecological morbidities and cure the current condition. Materials and Methods: An unmarried female patient of 14 years of age came to the outpatient department of Prasuti Tantra and Stree Roga of Sumandeep Ayurved Medical College &amp; Hospital with chief complaints of irregular, delayed, and scanty menstruation associated with weakness and white discharge per vagina for one and half year. The patient was assessed and diagnosed with subjective criteria for menstrual abnormalities, a pictorial chart for assessment of menstrual blood, and a Visual Analog Scale. The condition was managed with Rasapachaka syrup and Saptamrita Mishrana along with lifestyle modification and Rajaswala Paricharya (~do’s and don’ts during menstrual days). The treatment lasted for 3 months and the patient was followed up for the next 1 month. Results: The findings revealed satisfactory improvement after treatment. Conclusion: The findings revealed that Artavakshaya in lean adolescent girls could be managed effectively with these Ayurveda regimens and other modern interventions avoided.

Unveiling Makahiya Plant (Mimosa Pudica) Tea: A Natural Approach to Easing Dysmenorrhea Discomfort through Natural Process of Flouration

Dysmenorrhea, or painful menstrual cramps, is one of the most frequent gynecological illnesses. Several factors influence the expression of this biological event, including diet, lifestyle, cultural expectations and behaviors, and individual constitutions (Omani Samani et al., 2018). Mimosa Pudica is commonly utilized to treat dysmenorrhea and is often made via decoction, according to ethnobotanical research (Magtalas M. et al, 2023). The present study used phytochemical analysis to pinpoint vital compounds in Mimosa Pudica that aid in alleviating dysmenorrhea discomfort. The researchers also interviewed 15 participants who consume Mimosa Pudica tea during their menstrual cycle. The phytochemical analysis of Makahiya (Mimosa Pudica) has unveiled steroids, flavonoids, saponins, and tannins. These substances discovered through phytochemical analysis suggest that Makahiya (Mimosa Pudica) has therapeutic properties and can be used in easing dysmenorrhea. The researchers conclude that Mimosa Pudica tea can be used as an alternative treatment for dysmenorrhea providing more options to women who are suffering from this issue.

ANALISIS FAKTOR RISIKO DISMENORE PRIMER DAN DISMENORE SEKUNDER PADA MAHASISWI

While the incidence of dysmenorrhea is relatively high worldwide, the prevalence of dysmenorrhea reported in the literature varies substantially. This study aimed to analyze the risk factors for primary dysmenorrhea and secondary dysmenorrhea. This research is a cross analytical design. The sample in this study was all medical faculty students at Riau University in 2019-2022, namely 410 people. From the research results, it was found that there was a relationship between menstrual blood volume, history of food allergies and stress with the incidence of primary dysmenorrhea. Meanwhile, the incidence of secondary dysmenorrhea was related to age, menstrual cycle, history of the sample's gestational age at birth, history of low birth weight (LBW), history of emotional violence, stress and birth history of samples from preeclamptic mothers at the time of delivery. This research concluded that there were several significant findings regarding factors related to the occurrence of dysmenorrhea in Riau University medical students in 2019 - 2022. The research showed the importance of paying attention to factors such as the length of the menstrual cycle, history of food allergies, history of emotional violence, stress, and history of maternal preeclampsia in efforts to prevent and manage dysmenorrhea in the population. It is recommended that future research further explore the association between the identified risk factors and the incidence of dysmenorrhea, potentially revealing additional insights to guide clinical practice and public health initiatives.

Description of Female Students Skills in Carrying Out Endorphin Massage Techniques to Reduce Menstrual Pain

Introduction: Menstrual pain is pain felt during the menstrual cycle. The prevalence of primary Menstrual pain is generally experienced by adolescent girls aged 17-24 years by 67-90%. Menstrual pain has been identified as the most common menstruation-related cause of short-term school absenteeism among young girls. So menstrual pain in adolescents needs attention and information to provide appropriate treatment both pharmacologically and non-pharmacologically. Pharmacological treatment for menstrual pain can be overcome with analgesic drugs but causes addiction and dangerous side effects. One effective way to prevent menstrual pain is relaxation in the form of hand massage with endorphin massage techniques. This technique increases the release of endorphin and oxytocin hormones which function to reduce pain and based on research results show that the effectiveness of endorphin massage is more effective in reducing pain. Objective: The purpose of this research is to determine the description of female students' skills in carrying out endorphin massage techniques to relieve menstrual pain. Method: This study uses a descriptive research design. The sample in this study was determined using a quota sampling technique, namely as many as 32 respondents who fit the inclusion criteria. Result: The result of the research that respondents were able to carry out more endorphin massage technique, namely 20 people (62.5%), whereas 12 respondents (37.5%) were skilled at performing endorphin massage techniques. Conclusion: Most respondents were able to carry out the endorphin massage technique to reduce menstrual pain. In adolescent girls include menstrual conditions, unbalanced nutritional intake, eating and drinking patterns, non-compliance with Fe tablet consumption and lack of knowledge.

The Effect of Psychoeducation Based on Leventhal's Self-Regulation Model on Dysmenorrhoea in Nursing Students: A Single-Blind Randomised Controlled Study

The use of self-analgesics among women for dysmenorrhoea is common. Non-pharmacological methods can be employed to effectively cope with dysmenorrhoea. Psychoeducation based on Leventhal's Self-Regulation Model (SRM) is an affordable, easy, and non-pharmacological way that clinics can use to cope with dysmenorrhoea. This study aimed to investigate how psychoeducation affected dysmenorrhoea for nursing students using SRM. The sample consisted of 66 female students suffering from moderate-to-severe menstrual pain. A three-session psychoeducation based on SRM was applied to the intervention group. An 'Introductory Information Form', 'Visual Analogue Scale', 'Functional and Emotional Measure of Dysmenorrhoea (FEMD)', and 'Menstrual Symptom Questionnaire (MSQ)' were used to collect the data. All the measurements were carried out over three consecutive menstrual cycles. A generalised linear model was used to analyse the data. After receiving psychoeducation, the pain and functional and emotional symptoms of dysmenorrhoea mean scores significantly decreased in the intervention group compared to the control group (p < .05), whereas there was no significant difference between the groups' MSQ mean scores (p > .05). The psychoeducation reduced the severity of dysmenorrhoea pain and the functional and emotional impact levels of dysmenorrhoea and it was proved to be effective at helping the subjects cope with pain in the long term.

Evaluating the Impact of Long-Term GnRH Agonist Therapy on Pregnancy Outcomes in Endometriosis-Associated Implantation Failure and Pregnancy Loss

Purpose This study aimed to investigate the efficacy of long-term gonadotropin-releasing hormone (GnRH) agonist therapy in preventing endometriosis progression and relieving symptoms, particularly on pregnancy outcomes during thawed embryo transfer in patients experiencing endometriosis and recurrent implantation failure or recurrent pregnancy loss. Methods In individuals with clinical endometriosis and a history of recurrent implantation failure or recurrent pregnancy loss, we conducted a comparative analysis of clinical outcomes between those undergoing long-term GnRH agonist treatment for symptom relief, such as menstrual pain, followed by embryo transfer using Hormone Replacement Therapy (HRT) cycle, and those undergoing embryo transfer using an HRT cycle without GnRH agonist treatment. The study examined various clinical outcomes between the two groups. Results The primary outcomes included live birth rate (LBR), miscarriage rate, biochemical pregnancy rate, and perinatal complications. The GnRH agonist group showed significantly higher LBR than the control group (37.50% vs. 13.04%; p=0.02). Multivariable logistic regression analysis, adjusted for age and gravidity, showed significantly higher LBR in the GnRH agonist group compared to the control group (odds ratio: 15.3; 95% confidence interval: 2.30, 102.00; p=0.005). Conclusions The findings of this study suggested that employing a GnRH agonist in the embryo transfer protocol is effective for patients with endometriosis experiencing recurrent implantation failure or recurrent pregnancy loss.