For special populations such as people with a mental health issue or learning disability, a disconnect between the ability to accurately monitor and regulate exercise behaviour can lead to reduced levels of physical activity, which, in turn, is associated with additional physical or mental health problems. Activity pacing is a strategy used in clinical settings to address issues of pain amelioration, while self-pacing research is now well addressed in sport and exercise science literature. It has been proposed recently that these overlapping areas of investigation collectively support the development of self-regulatory, lifestyle exercise skills across broad population groups. Activity pacing appears to have substantial application in numerous development and rehabilitation settings and, therefore, the purpose of this short communication is to articulate how an activity pacing approach could be utilized among population groups in whom self-regulatory skills may require development. This paper provides specific examples of exercise practice across 2 discrete populations: children, and people with mental health and learning difficulties. In these cases, homeostatic regulatory processes may either be altered, or the individual may require extrinsic support to appropriately self-regulate exercise performance. A support-based exercise environment or approach such as programmatic activity (lifestyle) pacing would be beneficial to facilitate supervised and education-based self-regulation until such time as fully self-regulated exercise is feasible.LAY ABSTRACTActivity pacing is a practical means of supporting selfregulation in physical activity. This could be achieved through lifestyle support or in specific practical sport or physical activity situations, depending on the population. Improving the development of self-regulatory, lifestyle exercise skills across broad population groups could be helpful in addressing deficiencies in physical activity levels, which, in turn, can be associated with additional physical or mental health problems. This paper provides specific examples of pacing-based exercise practice across 2 example populations: children, and people with mental health and learning difficulties. In these cases, self-regulation processes may need to be developed, or require external support. Pacing is therefore relevant to different populations in different ways.