Abstract Great differences are observed in the way of living, the quality of living, and the type of property ownership in individual countries of the world. However, housing affordability is currently a significant issue in every developed country. At the same time, it is also an important factor of economic development on both the national and regional level. The paper is focused on the comparison of housing affordability in the Czech and Polish regions. The presented research combines four different commonly used indicators of housing affordability (financial and physical) into a newly defined index and applies it to the Czech Republic and Poland regions for the period 2020-2022. The aim is the comparison of Czech and Polish regions according to the selected housing indicators and calculated standard housing affordability index SAI, which is a newly created index compiled by the authors. The result of the research is a calculation of housing availability in a total of 30 Czech and Polish regions and a comparison of the development of housing availability in 2020 and 2022 in these regions. The result of the research is the finding that the availability of housing in the Czech regions is on average lower than in the Polish regions and, in addition, that the availability has decreased compared to 2020 in both the Czech and Polish regions by 2022.