In order to study the power of the air shock wave produced by the reactive material driven by explosion, the reaction behavior of the reactive material driven by explosion was analyzed by AUTODYN@ software, and the reaction law of the reactive material was obtained. Considering the chemical energy released by the reactive material, the calculation model of shock wave initial parameters is improved. Combined with dimensional analysis, the theoretical calculation model for overpressure of air shock wave generated by the reactive material driven by explosion is studied. The results show that, under the driving of explosion, the casing made of the reactive material does not react completely. The velocity of air shock wave produced by the charge with reactive material casing is higher than that of the charge with inert material casing. The predicted value of the theoretical calculation model is in good agreement with the experimental results, and the established model can well describe the attenuation law of the air shock wave overpressure generated by the reactive material driven by the explosion.