Overlap Percentages Research Articles

The airway device preference may affect the overlapping of the common carotid artery by the internal jugular vein.

Anatomical variation in the internal jugular vein (IJV), as well as its small size, tendency to collapse, and proximity to the common carotid artery (CCA) makes central venous cannulation via the IJV a technically challenging procedure, especially in pediatric patients. We evaluated the effects of laryngeal mask airway insertion and endotracheal intubation (ETT) on the anatomical relationship between the IJV and the CCA in neutral and 40° head away positions. After parental consent 92 patients with ASA physical status I-II, aged 0-17, undergoing elective urological surgery were enrolled and divided into two groups according to the airway management device used for anesthesia: Group laryngeal mask airway (n=63) and Group ETT (n=29). An ultrasonographic evaluation was performed before and after airway instrumentation at neutral and 40° head rotation. The IJV position in relation to the CCA was noted, and the overlap percentage of the CCA was calculated as the ratio of the CCA length covering by the internal jugular vein to the transverse diameter of the CCA. With no airway device insertion, the position of the IJV was found to be anterolateral to the CCA in the majority of patients (48.8% vs 35.3%, right vs left IJV) in the neutral head position. While there was no significant change in the overlap percentages of the CCA after laryngeal mask airway insertion in the neutral head position [48.71% vs 57.30% for the right IJV (difference in median: -21.20; 95% confidence interval (CI) of difference: -56.92 to 14.52; P=0.133); 52.54% vs 60.36% for the left IJV (difference in median: -10.3; 95% CI of difference: -41.49 to 20.89; P=0.128)], it increased significantly in the 40° head away position on both sides [50.11% vs 64.83% for the right IJV (difference in median: -55; 95% CI of difference: -84 to -25.24; P=0.01); 53.82% vs 71.20% for the left IJV (difference in median: -46; 95% CI of difference: -86.85 to -5.15; P=0.004)]. However, the overlap percentages of CCA decreased significantly on the right side with patients in a neutral head position (31.23% vs 6.27%, difference in median: 19; 95% CI of difference: -5.68 to 43.68; P=0.002) and on both sides in the 40° head away position [29.50% vs 16.19%, difference in median: 26; 95% CI of difference: 2.84 to 49.16; P=0.03 and 47% vs 31.94%, difference in median: 9.50; 95% CI of difference: -40.87 to 59.87; P=0.03 for the right and left sides, respectively] after ETT insertion. Laryngeal mask airway with 40° head rotation increases, whereas ETT decreases, the overlap percentage of CCA by IJV. Both head position and airway management methods have an influence on the overlap of the CCA by the IJV in pediatric patients.

Methods for Reducing Normal Tissue Complication Probabilities in Oropharyngeal Cancer: Dose Reduction or Planning Target Volume Elimination

Strategies to reduce the toxicities of head and neck radiation (ie, dysphagia [difficulty swallowing] and xerostomia [dry mouth]) are currently underway. However, the predicted benefit of dose and planning target volume (PTV) reduction strategies is unknown. The purpose of the present study was to compare the normal tissue complication probabilities (NTCP) for swallowing and salivary structures in standard plans (70Gy [P70]), dose-reduced plans (60Gy [P60]), and plans eliminating the PTV margin. A total of 38 oropharyngeal cancer (OPC) plans were analyzed. Standard organ-sparing volumetric modulated arc therapy plans (P70) were created and then modified by eliminating the PTVs and treating the clinical tumor volumes (CTVs) only (C70) or maintaining the PTV but reducing the dose to 60Gy (P60). NTCP dose models for the pharyngeal constrictors, glottis/supraglottic larynx, parotid glands (PGs), and submandibular glands (SMGs) were analyzed. The minimal clinically important benefit was defined as a mean change in NTCP of >5%. The P70 NTCP thresholds and overlap percentages of the organs at risk with the PTVs (56-59Gy, vPTV56) were evaluated to identify the predictors for NTCP improvement. With the P60 plans, only the ipsilateral PG (iPG) benefited (23.9% vs 16.2%; P<.01). With the C70 plans, only the iPG (23.9% vs 17.5%; P<.01) and contralateral SMG (cSMG) (NTCP 32.1% vs 22.9%; P<.01) benefited. An iPG NTCP threshold of 20% and 30% predicted NTCP benefits for the P60 and C70 plans, respectively (P<.001). A cSMG NTCP threshold of 30% predicted for an NTCP benefit with the C70 plans (P<.001). Furthermore, for the iPG, a vPTV56 >13% predicted benefit with P60 (P<.001) and C70 (P=.002). For the cSMG, a vPTV56 >22% predicted benefit with C70 (P<.01). PTV elimination and dose-reduction lowered the NTCP of the iPG, and PTV elimination lowered the NTCP of the cSMG. NTCP thresholds and the percentage of overlap of the PTV with organs at risk can predict which patients will benefit and inform future clinical trial design.

Scaling registration of multiview range scans via motion averaging

Three-dimensional modeling of scene or object requires registration of multiple range scans, which are obtained by range sensor from different viewpoints. An approach is proposed for scaling registration of multiview range scans via motion averaging. First, it presents a method to estimate overlap percentages of all scan pairs involved in multiview registration. Then, a variant of iterative closest point algorithm is presented to calculate relative motions (scaling transformations) for these scan pairs, which contain high overlap percentages. Subsequently, the proposed motion averaging algorithm can transform these relative motions into global motions of multiview registration. In addition, it also introduces the parallel computation to increase the efficiency of multiview registration. Furthermore, it presents the error criterion for accuracy evaluation of multiview registration result, which can make it easy to compare results of different multiview registration approaches. Experimental results carried out with public available datasets demonstrate its superiority over related approaches.

The analyses of human inherited disease and tissue-specific proteins in the interaction network

ObjectivesWith the announcement of human proteome and interaction data, it becomes possible to comprehensively investigate the tissue-expression and network properties of inherited disease proteins. In this study, our goal was to develop methods to map the disease and expression data and analyze the disorder-tissue associations. MethodsIn this paper, we manually classified the human disease proteins into 22 disorder classes and systematically analyzed the properties of disease proteins in different disorder classes. Then, we investigated the similarity of different disorder classes by computing the overlap of different disorder proteins and networks. We proposed two novel measures, Enrichment Ratio and P-value for comparative analysis of disease proteins across tissues and revealed the associations between disorder classes and tissues/cells. ResultsCompared with non-disease proteins, disease proteins tend to express in more tissues, have higher expression levels and interact with more other proteins in the network. The overlap percentages of networks are much higher than those of proteins, implying that different disorder classes usually influence each other by means of their interacting neighbors. The metabolic, muscular and hematologic proteins are related with most tissues/cells, and cancer proteins are closely associated with the disorders in immune cells. ConclusionThis paper provided novel methods to investigate proteome-wide disease proteins and their interacting networks in order to understand different disease’s associations.

Comparing neurocognition in severe chronic schizophrenia and frontotemporal dementia

Previous research has suggested cognitive similarities between schizophrenia and frontotemporal dementia. In the current study, we compared neurocognition in a group of hospitalised patients with chronic schizophrenia, who may have a more severe form of schizophrenia resembling Emil Kraepelin's dementia praecox, with patients with frontotemporal dementia. We hypothesised minimal group differences in cognitive performance, and a large overlap in between-group score distributions in each cognitive domain. Retrospective neuropsychological data for 26 patients with severe chronic schizophrenia and 34 patients with frontotemporal dementia (behavioural variant) was collated. Neuropsychological measures were categorised into 16 cognitive domains. Raw scores were converted into standardised z-scores for each measure, which were then averaged across measures within each domain. In addition to difference analysis, equivalence testing was utilised, whereby overlap percentages were computed to reflect the amount of score distribution overlap in each domain between groups. A statistically significant difference was observed only in the executive function sub-domain of Switching. Small-to-moderate and moderate effect sizes were noted in four other domains. Equivalence testing showed more than 85% of overlap in score distribution in most domains. Our findings suggest that some patients with severe chronic schizophrenia have cognitive deficits similar in degree and pattern to patients with frontotemporal dementia. The few differences observed between both groups of patients are important for differential diagnostic purposes. One limitation is the retrospective nature of the study. Suggestions for future research include longitudinal follow-up studies of these two patient populations and studies of aspects beyond neurocognition. An implication of our findings is that the 'dementia of schizophrenia' concept may be applicable to patients with severe chronic schizophrenia.

Characterization of material properties and heat source parameters in welding simulation of two overlapping beads on a substrate plate

This paper presents several aspects of characterization of welding heat source parameters in Goldak’s double ellipsoidal model using Sysweld simulation of welding of two overlapping beads on a substrate steel plate. The overlap percentages ranged from 40% to 80% in increments of 10%. The new material properties of the fused metal were characterized using Weldware and their continuous cooling transformation curves. The convective and radiative heat transfer coefficients as well as the cooling time t8/5 were estimated using numerical formulations from relevant standards. The effects of the simulation geometry and mesh discretization were evaluated in terms of the factor F provided in Sysweld. Eventually, the parameters of Goldak’s double ellipsoidal heat source model were determined for the welding simulation of overlapping beads on the plate and the simulated bead geometry, extent of the molten pool and the HAZ were compared with the macrographs of cross-sections of the experimental weldments. The results showed excellent matching, thus verifying this methodology for determination of welding heat source parameters.

Influence of overlap between the laser beam tracks on surface quality in laser polishing of AISI H13 tool steel

Polishing by laser beam radiation is a novel manufacturing process to modify the initial surface topography in order to achieve a desired level of surface finish. The performance of laser polishing (LP) is determined by an optimum combination of several key process parameters. In this regard, the overlap between two successive laser beam tracks is one of the important LP process parameters, which has a significant effect over the final surface quality. In the current study, influence of overlap between the laser beam tracks on surface quality was experimentally investigated during the laser polishing of AISI H13 tool steel. Surface areas were polished by using four different overlap percentages (e.g. 80%, 90%, 95%, and 97.5%) while applying the same energy density. The improvement of surface quality was estimated through the analysis of line profiling surface roughness Ra, areal topography surface roughness Sa, and material ratio function. Also, individual components of the surface quality, e.g. waviness and roughness, and their evolution during LP were statistically analyzed using the power spectral density and the transfer functions. Finally, as an example of the best achieved LP result, flat surface area was polished using optimum set of the process parameters improving surface quality by 86.7% through the reduction of an areal topography surface roughness Sa from 1.35μm to 0.18μm.

Role of Welding Parameters Using the Flux Cored Arc Welding Process of Low Alloy Steels on Bead Geometry and Mechanical Properties

Welding parameters have direct effects on the bead geometry, microstructure, and mechanical properties of low alloy steels. A series of experiments have been carried out to examine some of these parameters using the flux cored arc welding process (FCAW). In this article, an experimental study was conducted to investigate the influence of welding parameters in FCAW process particularly welding voltage and travel speed on weld bead dimensions. The study also includes the effects of bead overlap and deposition sequence on the parent material and the heat-affected zone (HAZ) properties. It was found that an increase in the welding voltage leads to an increase in the weld bead width, and the increase in the welding traverse speed leads to a decrease in the weld bead width. When studying the bead overlap percentages, it was found that the 50% bead overlap can be considered to be practically a better option than the higher percentages of bead overlap (i.e., 70-90%). The experimental investigation of studying the deposition sequence showed that there were no significant differences in the microstructure, hardness, and the size of the refined HAZ between the two proposed deposition sequences. However, a significant improvement in the microstructure and the size of the refined HAZ, and a reduction in the hardness were achieved after depositing the second welding bead, irrespective of the depositing sequence.

Two distinct patterns of spatial behaviour of female roe deer (Capreolus capreolus) in a mountainous habitat

The home range dynamics of eleven roe deer (Capreolus capreolus) females were studied from 1995 to 1999 in the Foreste Casentinesi National Park, northern Apennines, Tuscany, Italy. The study area is mountainous with almost complete forest cover (95%) and snow usually falls from late October to April. Data were collected with radio-tracking techniques: the annual and bimonthly home range, the overlap percentages of the Kernel home range of consecutive periods and of the same period in different years, and the linear distance between centres of home ranges were calculated and analysed. The first analysis showed two spatial behaviours: stationary and roaming. Roaming females had larger home ranges than stationary ones, and this difference was particularly apparent during winter. Furthermore, different behavioural patterns were found within the roaming roe deer: (i) winter altitudinal migration outside the summer home range; (ii) summer long-distance migration towards birthing and mating areas. The birth period and snow cover during winter are the most important factors influencing female spatial behaviour in this roe deer population.