This study aimed to evaluate the effect of bamboo species, specific pressure, and strand length on the properties of oriented strand boards (OSBs). Laboratory scale OSBs were made from two Indonesian bamboo species [tali (Gigantochloa apus) and andong (Gigantochloa pseudoarundinacea)] with three different strand lengths (75, 100, and 150 mm). For each bamboo species and strand length, OSBs were fabricated by bonding bamboo strands with 7% phenol formaldehyde resin and 0.5% wax emulsion based on their oven-dry weight. The layer structure of the face, core, and back of the three-layer cross-oriented board were 25%, 50%, and 25%, respectively. A specific pressure of 25 or 30 kg/cm2 was applied for 6 min at 160 °C. The targeted OSB density was 0.75 g/cm3. The results showed that OSBs from andong bamboo had better dimensional stability and bending strength than those from tali bamboo. The bending strength of bamboo-based OSBs increased with increased bamboo strand length. A strong interaction was found between bamboo species, specific pressure, and strand length on the mechanical properties of OSBs. The properties of all bamboo-based OSBs produced in this study conform with the requirements of the Japanese Industrial Standard JIS A 5908 (2015) and British Standard BS EN 300 (2006).