SummaryThe hydrolytic activity in extracts of human breast and bowel has been compared with adjacent infiltrating duct carcinoma and infiltrating carcinoma of the cecum, respectively. There are markedly increased levels of acid proteinase, arylamidase, tripeptidase, dipeptidases, acid phosphatase, and alkaline phosphatase in the tumor extracts over comparable adjacent normal extracts. Neutral proteinase is not present to any significant degree in the preparations examined. There is considerable hydrolytic activity in human mixed astrocytic and oligodendrogliocytic glioma as well as solid and papillary ovarian adenocarcinoma.
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