SESSION TITLE: Monday Abstract Posters SESSION TYPE: Original Investigation Posters PRESENTED ON: 10/21/2019 02:30 PM - 03:15 PM PURPOSE: After Hurricane Katrina, the New Orleans VA no longer had the inpatient or outpatient capacity to facilitate the work-up of Veterans with new lung nodules. Consequently, work-ups between 2005 and 2015 were either performed by VA providers at a contracted hospital site (internal) or outsourced through non-VA providers in the community (external). We sought to compare whether there were any significant differences in time to diagnosis, initiation of treatment, and mortality between those worked-up “externally” vs “internally”. METHODS: Key data points were collected via retrospective chart review including patient demographics; medical co-morbidities; time from detection of lung nodule to pulmonary referral, pathologic diagnosis, and initiation of treatment; cancer stage at diagnosis; and overall survival. The patients were separated into two cohorts based on whether the diagnostic work-up was performed internally or externally. The mean time to diagnosis and treatment was compared between the two groups using a two-tailed T test. Differences in mortality was estimated by comparing the mean survival time between the two groups using a Tarone-Ware test. RESULTS: 518 Veterans between 2005 and 2015 were diagnosed with lung cancer in the SLVHCS. Of the 241 patients who met inclusion criteria, 195 underwent an internal work-up and 46 underwent an external work-up. Patients in the internal group were younger on average than the external group (65.0 vs 69.1 years, P =0.004). Average time to pathologic diagnosis was 49.6 days (SD 32.1 days) in the internal group and 58.7 days (SD 39.2 days) in the external group (P = 0.12). Average time to initiation of treatment was 89.8 days (SD 51.7 days) in the internal group and 107 days (SD 42.8 days) in the external group (P = 0.033). The incidence of patients with stage III or IV cancer at time of diagnosis was 63% in the internal group versus 35% in the external group (P = < 0.005). The mean survival time was 1039.0 days (SD 81.6 days) in the internal group and 1199.5 days (SD 120.0 days) in the external group (P = 0.007). CONCLUSIONS: There was a statistically significant shorter time to initiation of lung cancer treatment for Veterans worked-up within the VA system compared to those who were outsourced externally. There were no significant differences in the time from detection of lung nodule to time of pathologic diagnosis. Veterans who were worked-up externally had a statistically significant increased mean survival time, although this cohort was composed of patients with less advanced disease at time of diagnosis. CLINICAL IMPLICATIONS: Natural disasters, such as Hurricane Katrina, can have significant impacts on the VA healthcare system of that region. This can potentially lead to significant delays in care to Veterans residing in the affected area, and additional outside resources may be warranted to ensure timely and adequate access to care. DISCLOSURES: No relevant relationships by Corey Costantino, source=Web Response No relevant relationships by Karin Halvorson, source=Web Response No relevant relationships by Frederick Jung, source=Web Response