COVID-19 Outbreak In Wuhan Research Articles

Workplace Violence and Burnout among Health Workers Two Years after the COVID-19 Outbreak in Wuhan, China: The Chain Mediation Effect of Sleep Disturbance and Work Ability.

Health workers (HWs) faced considerable psychosocial hazards during the COVID-19 pandemic, which profoundly affected their occupational health and job performance. The potential indirect relationship between workplace violence (WPV) and burnout among HWs needs to be further explored. The purpose of this study is to examine the chain mediating effects of sleep disturbance and work ability in the relationship between WPV and burnout among HWs. A cross-sectional study was conducted in a secondary hospital two years after the COVID-19 outbreak in Wuhan, China. A sample of 571 HWs was recruited using a cluster sampling method, achieving a response rate of 80.06%. Participants completed self-report questionnaires that included demographic information and measures of WPV, burnout, sleep disturbance, and work ability. The prevalence rates of burnout and WPV among HWs two years after the COVID-19 outbreak were 37.30% and 31.52%, respectively. WPV was significantly associated with burnout (β = 0.446, p < 0.001). Sleep disturbance was identified as a mediator in the relationship between WPV and burnout (β = 0.063, 95% CI: 0.027-0.105), accounting for 14.13% of the total effect. Similarly, work ability also played a mediating role in this relationship (β = 0.142, 95% CI: 0.065-0.225), accounting for 31.84%. Additionally, both sleep disturbance and work ability exhibited a chain mediation effect on the association between WPV and burnout (β = 0.020, 95% CI: 0.008-0.036), and the total indirect effect accounted for 50.67%. Among Chinese HWs, WPV exerts significant direct and indirect effects on burnout symptoms, mediated by sleep disturbance and work ability. This finding provides valuable empirical insights for designing interventions to mitigate the adverse effects of psychosocial factors such as WPV and burnout among HWs. After exposure to WPV, measures focused on reducing sleep disturbance and enhancing work ability may prove effective in alleviating burnout in subsequent interventions.

Public Health Reporting in the China’s TV News: A Case Study of Early Stage of COVID-19 Outbreak

initial outbreak of COVID-19 in Wuhan in December 2019 prompting swift nationwide measures. Amidst the escalating crisis has contribute to China enforced temporary closures and exit controls in Hubei province, a pivotal move in curbing the virus's spread on January 23, 2020. This paper aims to explore the role of CCTV News, as the "mouthpiece" of the Party and the government in shaping public opinion during the COVID-19 epidemic. This preliminary study utilizes content analysis methods to examine the framework of COVID-19 news coverage, with a focus on a specialized TV news program aired between January 20 and February 20, 2020. The findings show how positive publicity and humanistic care initiatives have been instrumental in stabilizing public sentiment and effectively conveying China's perspective amidst the crisis. Subsequently, on January 28, 2020, the Publicity Department of the State Administration of Radio, Film and Television coordinated the programming of national satellite TV programs prioritizing epidemic prevention and control coverage, curtailing entertainment programming, and issuing comprehensive programming guidelines to all 36 satellite TV stations. This concerted effort is seen as a strategic shift that has significantly increased the dissemination of information, addressed public concerns, and steered public opinion in support of the nation's fight against the epidemic.

Effectiveness of seven oral traditional Chinese medicines against mild or moderate COVID-19: An updated systematic review and network meta-analysis

BackgroundSevere acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for the outbreak of COVID-19 in Wuhan, China. As a highly infectious epidemic, SARS-CoV-2 rapidly evolves. Presently, COVID-19 coexists with humans, mainly with mild or moderate disease. The latest Guidelines for the Diagnosis and Treatment of COVID-19 (trial version of the 10th Edition) recommend several oral traditional Chinese medicines (TCMs) for treatment. This study aims to evaluate the evidence-based benefits of these TCMs as adjunctive therapies to conventional western medicine (CWM) for patients with mild or moderate COVID-19. MethodsWe conducted a systematic review and meta-analysis adhering to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, utilizing the PRISMA checklist. We searched PubMed, Cochrane Library, Embase, CNKI, and Wan-Fang databases to retrieve randomized controlled trials and retrospective cohort studies of TCM in combination with CWM on the treatment of mild or moderate COVID-19 that were published as of December 25, 2023. A network meta-analysis using the frequency model was employed to evaluate the benefits of different interventions. ResultsA total of 30 eligible studies, enrolling 4144 participants, utilized 7 marketed oral TCMs in China. Compared with CWM alone, the integration of TCMs with CWM can significantly reduce severe conversion rate. This combined approach also enhances the clinical effective rate, shortens the negative conversion time of nucleic acid, and improves both symptoms and blood biochemical markers in patients. The network meta-analysis provided preliminary evidence of the superiority of specific TCMs for various outcomes: Qingfei Paidu for raising the CT improvement rate and clinical effective rate, and shortening the negative conversion time of nucleic acid; Huashi Baidu for reducing severe conversion and improving cough; Xuanfei Baidu for improving fatigue; Jinhua Qinggan for improving fever; Lianhua Qingwen for shortening the recovery time of fatigue and cough; and Shufeng Jiedu for shortening the recovery time of fever. ConclusionsTCM in combination with CWM may be beneficial for patients with mild or moderate COVID-19. Each TCM may have distinct benefits in COVID-19.

What COVID-19 Vaccine Distribution Disparity Reveals About Solidarity

What COVID-19 Vaccine Distribution Disparity Reveals About Solidarity

Virtual mutual care practices of Chinese people amid censorship during the initial COVID-19 outbreak in Wuhan, China

The initial outbreak of the COVID-19 pandemic hit Wuhan, China, in early January 2020, and restrictive lockdown measures were implemented. Risks of transmission and the lockdown measures severely disrupted everyday life and affected the well-being of local residents. Applying institutional ethnography and autoethnography, this study focuses on the virtual mutual care of Chinese social network site users, which attended to the hardship of local people through activities in cyberspace. Not only were the virtual mutual care activities lifesaving, as they tackled critical challenges of the affected residents, but they also had radical meanings, as they strived for solidarity and justice in the context of crisis.

Trailing World Health Assembly Resolution 73.1: Pathway to Quick and Accurate Determination of the Source of Outbreak of COVID-19 in Wuhan, China.

For more than four years now, the objective of determining the source of the outbreak of COVID-19 in Wuhan, China and the route of transmission of the infection to the human population has not been achieved despite existing capacity in molecular epidemiology and World Health Assembly Resolution mandating that objective. This study seeks to ascertain the reasons for failure to achieve that objective and to propose feasible alternative strategies to attain that objective quickly and accurately. Exploratory research was adopted, applying the tools of input-output device, data extraction, management by objective, rational decision approach and the deductive model. Fitting the objective of determining the source of the outbreak of COVID-19 as expected output, the actions of key players in the pandemic response (fitted as processors) were evaluated for consistence or otherwise in transforming data/inputs to achieve the output/objective. The study found that the World Health Assembly (WHA) Resolution 73.1 (9 (6)) mandating the World Health Organization (WHO) to pursue the objective of determining the source of the outbreak of COVID-19 was not diligently and committedly implemented; that the WHO and China have deliberately evaded that objective; that previous and ongoing studies focusing on the circulation of SARS-CoV-2 in other countries and similar themes are diversionary and unnecessary workload that depart from the core objective; and that adopting a five-point alternative strategy will ensure the attainment of the core objective within 14 days, including: (i) re-phrasing of the WHA mandate for specificity; (ii) subjecting all possible pathways of transmission to scrutiny; (iii) adopting “confirmed” genetic sequences of SARS-CoV-2 for subsequent use in molecular epidemiology; (iv) establishing a ‘red circle’ of 2 km radius from the Huanan wet market for top-priority epidemiologic investigation; (v) review of Resolution WHA73.1(9 (6)) at upcoming WHA to expressly prescribe unfettered right of access to the international study team and sanction for non-compliance. The study concludes that determining the source of the outbreak of COVI-19 in Wuhan, China is an important objective that should be accomplished within 14 days considering existing capacity in molecular epidemiology, if avoidable impediments are removed.

The role of vaccine in COVID-19

The sudden outbreak of COVID-19 in Wuhan, China, has brought sudden harm to people. Under such circumstances, many vaccines have been invented and created, and all kinds of vaccines also carry their own advantages and disadvantages. It is essential for population to understand the working principle and basic production method of each vaccine. At present, there are many vaccines for the novel coronavirus epidemic, but there are three vaccines that mainly occupy the market. Recent study has found that adenovirus vaccine is effective to safe people from the virus, but it can give people some bad symptoms. mRNA vaccines can increase the immune system after a second or multiple doses, especially in people over 40 years-old. In the meantime, recombinant protein COVID-19 vaccine has a strong immune response with stability of the vaccine immunity. In this paper, the most basic principles and the lowest logic of these vaccines are introduced respectively. In addition, these vaccines are combined with some studies on clinical symptoms. This article also analyzes the shortcomings and benefits of these different vaccines, and this review will recommend methods to avoid infection based on the structure of all COVID-19 vaccines and pathogens.

Loathsome Hui parasites: Islamophobia, ethnic chauvinism, and popular responses to the 2020 Wuhan coronavirus outbreak

ABSTRACT On 31 January 2020 in the midst of the outbreak of COVID-19 in Wuhan, China the city’s Party Secretary, Ma Guoqiang admitted in a televised interview to feeling “guilty and remorseful,” about the city government’s failures to contain the virus. In response, netizens on Weibo directed visceral abuse at Ma, an ethnic Hui Muslim, about his faith and loyalty to the party. The attacks came just months after the publication of leaked documents from national party officials calling Islam a “virus” and vowing to stop its “contagion.” Using discourse analysis of posts regarding Ma from January and February 2020, this paper examines how online discussion of Ma exemplifies Islamophobic attitudes of netizens and illuminate the exclusory ethnic politics that unfold in the process of national boundary setting in China. These findings will also illuminate how Muslims become scapegoats for crisis in non-Muslim countries, particularly those under authoritarian governance.

Guardians of Safety: Indonesian Nurses and COVID-19 PPE Practices

BackgroundSince the emergence of the COVID-19 outbreak in Wuhan, China, the world has undergone drastic changes. The Delta variant has high transmissibility and evades human cellular defenses. Data from the World Health Organization (WHO) recorded over 31.654 million cases and 4 million COVID-19 deaths as of December 2022. Hospitals have faced challenges in patient management and healthcare worker protection. This study discusses the relationship between nurses' knowledge, attitudes, and behaviors regarding the use of personal protective equipment in Indonesian COVID-19 referral hospitals. MethodsThis study utilized a quantitative analytical observational method with a cross-sectional approach. The research was conducted in four COVID-19 referral hospitals in the Yogyakarta Special Region in Indonesia. ResultsThis study shows that there is no significant relationship between attitudes and behaviors in the use of PPE; however, a positive correlation exists. ConclusionMost nurses in COVID-19 isolation wards demonstrate good knowledge, attitudes, and behaviors toward the use of PPE. There is a positive correlation between knowledge and attitudes, as well as nurses' behaviors in using PPE.

The influence of changes in the Chinese COVID-19 prevention and control policies on mental health of medical staff: A network analysis

BackgroundShortly after the first outbreak of COVID-19 in Wuhan, the disease spread rapidly around the world. Previous findings reported an increase in mental health problems among Chinese medical staff, but there was a lack of research following changes in COVID-19 prevention and control policies. MethodsMedical staff were recruited separately in China from 15 to 16 December 2022 (N = 765, wave 1) and from 5 to 8 January 2023 (N = 690, wave 2). All participants completed the assessments of Generalized Anxiety Disorder-7, the Patient Health Questionnaire-9 and the Euthymia Scale. Network analysis was used to explore the relationships between symptoms both within and across depression, anxiety and euthymia. ResultsMedical staff showed worse anxiety, depression and euthymia at wave 2 than at wave 1. Depression, motor, restlessness and uncontrollable worrying showed high centrality (i.e., strength, expected influence, closeness) at wave 1, but higher at peak. Meanwhile, motor symptoms and restlessness showed the strongest connection between different mental disorders at both wave 1 and wave 2. The network structure was stable over time after the relaxation of the infection policy.Limitations.Our participants were not a random sample and the assessments were based on self-reports. ConclusionsThis study indicated the changes in central and bridging symptoms in medical staff at different stages after lifting of restrictions and the withdrawal of testing requirements, which provided management suggestions for the Chinese government and hospitals, as well as clinical guidance for psychological interventions.

Detention of citizen journalists who reported on the outbreak of COVID-19 in Wuhan

Detention of citizen journalists who reported on the outbreak of COVID-19 in Wuhan

Risk assessment of infectious disease epidemic based on fuzzy Bayesian network.

The prevention and control of infectious disease epidemic (IDE) is an important task for every country and region. Risk assessment is significant for the prevention and control of IDE. Fuzzy Bayesian networks (FBN) can capture complex causality and uncertainty. The study developed a novel FBN model, integrating grounded theory, interpretive structural model, and expert weight determination algorithm for the risk assessment of IDE. The algorithm is proposed by the authors for expert weighting in fuzzy environment. The proposed FBN model comprehensively takes into account the risk factors and the interaction among them, and quantifies the uncertainty of IDE risk assessment, so as to make the assessment results more reliable. Taking the epidemic situation of COVID-19 in Wuhan as a case, the application of the proposed model is illustrated. And sensitivity analysis is performed to identify the important risk factors of IDE. Moreover, the effectiveness of the model is checked by the three-criterion-based quantitative validation method including variation connection, consistent effect, and cumulative limitation. Results show that the probability of the outbreak of COVID-19 in Wuhan is as high as 82.26%, which is well-matched with the actual situation. "Information transfer mechanism," "coordination and cooperation among various personnel," "population flow," and "ability of quarantine" are key risk factors. The constructed model meets the above three criteria. The application potential and effectiveness of the developed FBN model are demonstrated. The study provides decision support for preventing and controlling IDE.

COVID-19 epidemic phases and morbidity in different areas of Chinese mainland, 2020.

In the early stage of COVID-19 epidemic, the Chinese mainland once effectively controlled the epidemic, but COVID-19 eventually spread faster and faster in the world. The purpose of this study is to clarify the differences in the epidemic data of COVID-19 in different areas and phases in Chinese mainland in 2020, and to analyze the possible factors affecting the occurrence and development of the epidemic. We divided the Chinese mainland into areas I, I and III, and divided the epidemic process into phases I to IV: limited cases, accelerated increase, decelerated increase and containment phases. We also combined phases II and III as outbreak phase. The epidemic data included the duration of different phases, the numbers of confirmed cases, asymptomatic infections, and the proportion of imported cases from abroad. In area I, II and III, only area I has a Phase I, and the Phase II and III of area I are longer. In Phase IV, there is a 17-day case clearing period in area I, while that in area II and III are 2 and 0 days, respectively. In phase III or the whole outbreak phase, the average daily increase of confirmed cases in area I was higher than that in areas II and III (P = 0.009 and P = 0.001 in phase III; P = 0.034 and P = 0.002 in the whole outbreak phase), and the average daily in-hospital cases were most in area I and least in area III (P = 0.000, P = 0.000, and P = 0.000 in phase III; P = 0.000, P = 0.000, and P = 0.009 in the whole outbreak phase). The average number of daily in-hospital COVID-19 cases in phase III was more than that in phase II in each area (P = 0.000, P = 0.000, and P = 0.001). In phase IV, from March 18, 2020 to January 1, 2021, the increase of confirmed cases in area III was higher than areas I and II (both P = 0.000), and the imported cases from abroad in Chinese mainland accounted for more than 55-61%. From June 16 to July 2, 2020, the number of new asymptomatic infections in area III was higher than that in area II (P = 0.000), while there was zero in area I. From July 3, 2020 to January 1, 2021, the increased COVID-19 cases in area III were 3534, while only 14 and 0, respectively, in areas I and II. The worst epidemic areas in Chinese mainland before March 18, 2020 and after June 15, 2020 were area I and area III, respectively, and area III had become the main battlefield for Chinese mainland to fight against imported epidemic since March 18, 2020. In Wuhan, human COVID-19 infection might occur before December 8, 2019, while the outbreak might occur before January 16 or even 10, 2020. Insufficient understanding of COVID-19 hindered the implementation of early effective isolation measures, leading to COVID-19 outbreak in Wuhan, and strict isolation measures were effective in controlling the epidemic. The import of foreign COVID-19 cases has made it difficult to control the epidemic of area III. When humans are once again faced with potentially infectious new diseases, it is appropriate to first and foremost take strict quarantine measures as soon as possible, and mutual cooperation between regions should be explored to combat the epidemic.

An Agenda-Setting Account for Psychological Typhoon Eye Effect on Responses to the Outbreak of COVID-19 in Wuhan.

During the outbreak of COVID-19 in Wuhan in 2020, we conducted a nationwide survey of 8170 respondents from 31 provinces/municipalities in China via Sojump to examine the relationship between the distance to respondents' city of residence from Wuhan and their safety concerns and risk perception of the epidemic that occurred in Wuhan City. We found that (1) the farther (psychologically or physically) people were from Wuhan, the more concerned they were with the safety of the epidemic risk in Wuhan, which we dubbed the psychological typhoon eye (PTE) effect on responses to the outbreak of COVID-19; (2) agenda setting can provide a principled account for such effect: the risk information proportion mediated the PTE effect. The theoretical and managerial implications for the PTE effect and public opinion disposal were discussed, and agenda setting was identified to be responsible for the preventable overestimated risk perception.

Psychological Impact of COVID-19 Lockdown and Its Evolution: A Case Study Based on Internet Searching Data during the Lockdown of Wuhan 2020 and Shanghai 2022.

It has been three years since the initial outbreak of COVID-19 in Wuhan, China, which incurred huge damage both physically and psychologically on human's normal life. As a prevention measure, the lockdown was first adopted by Wuhan, then by a long list of Chinese cities and many other major cities around the world. Lockdown is the most restrictive social distancing strategy, turning out effective in mitigating the spreading of COVID-19 on the community level, which, however, cuts off all social interactions and isolates healthy people from each other. The isolated nature of the lockdown could induce severe mental health issues, forming one major source of depression and domestic violence. Given the potential side effect, a comprehensive investigation based on reliable data sources is needed to evaluate the real psychological impact of COVID-19 lockdown and its evolution over time, particularly in the time when the Omicron variant, known for its low death risk, dominates the pandemic. Based on the Baidu Searching Index data collected for Wuhan and Shanghai, two major cities in China that suffered from long-lasting (over two months) lockdowns in 2020 and 2022, respectively, it is found that the major psychological issue during the lockdown period is not induced by the spreading of COVID-19, but by the execution of lockdown. With the deepening of knowledge about COVID-19 and the decrease in the death risk, the psychological impact of lockdown keeps increasing, while the impact of virus spreading becomes less important and even irrelevant to depression and domestic violence issues. The findings reveal that from the psychological perspective, the negative effect of lockdown already overweighs the positive one, which is especially true for the Omicron variant provided its almost ignorable death risk. Therefore, it is necessary to re-evaluate the yield and cost of lockdown for those countries where the COVID-19 pandemic has not yet come to an end.

Rumor Detection of Covid-19 Related Microblogs on Sina Weibo

Since the outbreak of COVID-19 in Wuhan in 2019, Sina Weibo has become a platform for rumors to spread rapidly with more than 200 million daily active users. Based on this, we focus on the epidemic-related rumors on Sina Weibo during the epidemic. By summarizing the features extracted by feature engineering in the research of rumor detection from 2011 to now, we find that the existing features have low utilization rate of the user's geographical location property. Although the public display of the user's IP geographical location in Sina Weibo since April 28, 2022 has greatly improved the authenticity of this property, its utilization is still limited to extracting the explicit feature of IP geographical location. Moreover, the existing research has not paid attention to the filtering mechanism of the platform when extracting features, and has taken advantage of this phenomenon.According to the shortcomings of the existing research, we put forward two new indicators based on the filtering mechanism of Sina Weibo, the available comments and the first-class available comments. The available comments represent comments in the comment area of each microblog that have not been filtered by the filtering mechanism. The first-class available comments represent available comments that directly reply to the original microblog. Based on the new indicator of first-class available comments and users’ IP geographical location property, we further put forward 10 new features. Finally, we train seven classifiers, including logistic regression, SVM based on linear kernel, SVM based on RBF kernel, Naive Bayes, random forest, DNN and CNN. By comparing the prediction effects of each classifier and the prediction effects of the classifier before and after adding new features, it is concluded that the random forest classifier performed best in this application scenario, and the new features can improve the accuracy of random forest classifier by 1.33%, the precision rate of positive cases by 2%, the precision rate of negative cases by 5%, the recall rate of positive cases unchanged and the recall rate of negative cases by 14%.

A wailing wall in cyberspace: Loneliness, censorship, and collective memory – in memory of Dr. Li Wenliang, the whistle blower

As the whistle blower of the outbreak of Covid-19 in Wuhan, Dr. Li Wenliang was dismissed as the spreader of rumors and punished by the authorities. His later death from the coronavirus outraged the netizens in China on various social platforms. His post on Weibo, written by Dr. Li on the day he was finally diagnosed as infected, has thus become a wailing wall in cyberspace. It has invited millions of Weibo comments below, both from those who lost their loved ones in the outbreak and netizens in general. The post functions as a monument in cyberspace for people to commemorate the bereft in the coronavirus outbreak in Wuhan, the first place where Covid-19 was reported. Considering the transmediality of cyberspace of our modern times, the phenomenon of online mourning urges a semiotic explanation, especially when it concerns a figure who only became famous after his death. The study aims to conceptualize the dynamics of collective memory with the monument in cyberspace following the insights of Eco’s concept of “the open text”. The wailing wall in cyberspace functions as a mnemonic text for members of society, which interacts with the collective memory restored in the social sphere. Moreover, censorship also played an important role in the formation of the wailing wall. All these features are brought together to make the wailing wall in the cyberspace a unique spectacle in online culture, which paves the way for further discussions in the future.

Effect of Wuhan's anti-COVID-19 lockdown on its pace of life and metaphorical temporal perspective.

The online version contains supplementary material available at 10.1007/s40167-022-00113-4.

Research on the Audit of Public Health Emergencies: A Case Study of The Online Audit of the COVID-19 Epidemic in Wuhan

Since COVID-19 outbreak, governments at all levels across the country have devoted huge amount of money to the epidemic prevention and control, in order to effectively cope with the emergency and to ensure that the effective use of funds, the public put forward higher request to the effective use of fiscal funds, to some extent also regulations to Social supervision department, in particular, the audit department has put forward higher requirements. Therefore, this paper investigated the online audit of COVID-19 outbreak in Wuhan to study its role in the process of epidemic prevention and control. This paper mainly analyzes the organizational structure of audit institutions and the status of online audit through sampling survey of audit staff in Wuhan and college students and other positions, and analyzes various problems in online audit work from multiple perspectives and puts forward solutions based on questionnaire survey and statistics. For some preventable emergencies, we can use data capture to analyze and predict the existing situation to strengthen the effect of prevention; We can also use the government's financial data on public expenditure to judge whether enterprises can independently face the public health crisis in the future. In addition, we also put forward some suggestions to deal with the problem of late information disclosure under the pandemic, and reduce the audit risk.

Progress of Hollow Materials in Diagnosis of Covid-19

Since the outbreak of COVID-19 in Wuhan, China, it has dramatically changed the global geopolitics, economics, and even society standard norms. The present world scenario is changed regarding business, traveling, and education. Rapid global dissemination and the high mortality rate of coronaviruses are the greatest challenges for drug developers. It will be moving forward toward the identification and treatment of emerging coronaviruses with the aid of nanotechnology. The COVID-19 pandemic raised the question of researchers’ capability to manage this dilemma in a short period. In the present review, we described how hallow material could be developed as a pro-drug that shows an excellent therapeutic effect. Hollow nanoparticles that exploration of antiviral or diagnostic agents against emerging coronaviruses. Hollow nanomaterials in vaccine development are essential because hollow nanocomposites are suitable for mimicking viral structures and antigen delivery. A biosensor that generates a signal from a transducer for comparing and analyzing biological conjugates such as cell receptors, antibodies, RNA, DNA, and nucleic acids. Different biosensors, such as graphene-based biosensors, nanoplasmonic sensor chips, nanomaterial biosensors, electrochemical biosensors, dual modality biosensors, and optical biosensors, have several advantages, characteristics, and a wide range of applications, most remarkably in medical treatment and are used for monitoring and diagnosis. This review focuses on modern experimental studies to identify intelligent and innovative bio/nanomaterials and matrices for developing targeted and controlled drug release systems, nanosensors and nanovaccines to combat pathogenic viruses.