You have accessJournal of UrologyKidney Cancer: Localized: Surgical Therapy II (PD11)1 Apr 2020PD11-03 ASSESSMENT OF OTHER-CAUSE MORTALITY IN T1AN0M0 RENAL CELL CARCINOMA PATIENTS WITH 15 YEARS OF FOLLOW-UP: A SEER-BASED ANALYSIS Angela Pecoraro*, Sophie Knipper, Carlotta Palumbo, Giuseppe Rosiello, Stefano Luzzago, Marina Deuker, Zhe Tian, Shahrokh F. Shariat, Fred Saad, Alberto Briganti, Cristian Fiori, Francesco Porpiglia, and Pierre I. Karakiewicz Angela Pecoraro*Angela Pecoraro* More articles by this author , Sophie KnipperSophie Knipper More articles by this author , Carlotta PalumboCarlotta Palumbo More articles by this author , Giuseppe RosielloGiuseppe Rosiello More articles by this author , Stefano LuzzagoStefano Luzzago More articles by this author , Marina DeukerMarina Deuker More articles by this author , Zhe TianZhe Tian More articles by this author , Shahrokh F. ShariatShahrokh F. Shariat More articles by this author , Fred SaadFred Saad More articles by this author , Alberto BrigantiAlberto Briganti More articles by this author , Cristian FioriCristian Fiori More articles by this author , Francesco PorpigliaFrancesco Porpiglia More articles by this author , and Pierre I. KarakiewiczPierre I. Karakiewicz More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000000845.03AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Five-year other cause mortality (OCM) after nephrectomy for non-metastatic renal cell carcinoma (nmRCC) should be marginal in properly selected surgical candidates. We examined 5-year OCM rates as a quality of care indicator for patient selection. METHODS: Within the Surveillance, Epidemiology, and End Results database (1997-2011), we identified 59267 RCC patients treated with either radical (RN, 27804, 46.9%) or partial nephrectomy (PN, n=31463, 53.1%). Temporal trends and multivariable Cox regression analyses assessed 5-year OCM. Data were stratified according to age group (<60 vs. 60-70 vs. >70 years), year of diagnosis (1997-2001 vs. 2002-2006 vs. 2007-2011), race, marital status, gender, and socio-economic status (SES). RESULTS: The overall OCM rates for the entire cohort at 5 years of follow-up was 4.7% and decreased from 9.4 to 5.6% over the study span (-3.8%, p<0.001). The greatest decrease in 5-year OCM rates over time was recorded in patients >70 years (17.0-9.6%, slope: -0.6%/year), as well as in African-Americans (12.0-6.2%, slope: -0.3%/year) and in males (8.9-4.7%, slope: -0.3%, all p<0.001). Multivariable Cox regression models corroborated these findings. CONCLUSIONS: An important OCM decrease was recorded over the study span. Nonetheless, further improvement may be accomplished, especially in African-Americans, unmarried and older individuals, who exhibited higher OCM rates than others. These three groups may represent ideal targets for better patient selection based on OCM considerations. Source of Funding: None © 2020 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 203Issue Supplement 4April 2020Page: e253-e254 Advertisement Copyright & Permissions© 2020 by American Urological Association Education and Research, Inc.MetricsAuthor Information Angela Pecoraro* More articles by this author Sophie Knipper More articles by this author Carlotta Palumbo More articles by this author Giuseppe Rosiello More articles by this author Stefano Luzzago More articles by this author Marina Deuker More articles by this author Zhe Tian More articles by this author Shahrokh F. Shariat More articles by this author Fred Saad More articles by this author Alberto Briganti More articles by this author Cristian Fiori More articles by this author Francesco Porpiglia More articles by this author Pierre I. Karakiewicz More articles by this author Expand All Advertisement PDF downloadLoading ...