Objective To study the application of evidence-based nursing in senile patients with osteoporosis and femoral neck fracture.Methods According to patients' nursing problems such as pressure sore,respiratory tract infection,urinary tract infection,constipation,dislocation of hip joint,deep venous thrombosis,and mental disorder and so on,we proposed predictive nursing strategies and implemented the evidence-based nursing interventions and fully used all aspects of support. Meanwhile,health education activities were conducted.Results Among 56 patients,the complications were effectively reduced and fracture were effectively prevented,all patients recovered smoothly after operations.Conclusions Evidence-based nursing can help prevent the complications of osteoporotic hip fracture and effectively increase the quality of life in osteoporotic hip fracture patients. Key words: Osteoporosis ; Evidence-based nursing; Femoral neck fracture