Osseous Hyperplasia Research Articles

Calcification of Stylohyoid Ligament Leading to Eagle’s Syndrome: An Atypical Presentation

Background Elongated styloid process is seen in 5% of individuals. This elongation presents with oropharyngeal pain and dysphagia; however 50-55% cases are asymptomatic. The proposed aetiology is osseous hyperplasia of the styloid process and styloid ligaments secondary to surgical intervention or pharyngeal trauma. Elongated styloid process or calcification of styloid ligament may impinge on cranial nerves and compress the carotid artery. Case Presentation Here we present a case of 48-year old male who presented with neck pain and foreign body sensation for last two months. To diagnose the cause of pain, the patient underwent a CT scan that revealed calcification of bilateral styloid ligaments. Conclusion CT scan is the ideal imaging investigation in Eagle syndrome for diagnosis and surgical planning

PC226: Subpontic osseous hyperplasia and intrabony defect treatment: a clinical report

PC226: Subpontic osseous hyperplasia and intrabony defect treatment: a clinical report

Subpontic osseous hyperplasia: report of two cases

AbstractSubpontic osseous hyperplasia is a non‐neoplastic growth of bone under the pontics of fixed partial dentures, whose pathogenesis is unknown. It is considered a common, not well‐known and under‐diagnosed lesion. Its clinical and radiographic features are diagnostic, and its recognition will help avoid diagnostic or therapeutic procedures unnecessary to the patients. We present two cases of subpontic osseous hyperplasia and discuss its differential diagnosis and current concepts on pathogenesis and management.

Hemiatrophy of the brain: a report of two cases

Introduction: Hemiatrophy of the brain is the radiological finding, in the patients with seizure and/ or mental retardation and hemiparesis, usually due to insult to developing brain in fetal and early childhood. Other imaging feature is the compensatory osseous hyperplasia. This condition, also known as Dyke-Davidoff-Masson Syndrome is a rare entity and we report two such cases.JSSN 2015; 18 (1), Page: 26-28

Congenital Infiltrating Lipomatosis of the Face: A Case Report

Congenital infiltrating lipomatosis of the face is a rare lesion that comprises a subgroup of lipomatous tumor-like lesions of infancy and childhood. It is characterized by (1) no encapsulation, (2) diffuse infiltration of mature adipose tissue over normal muscle fiber and surrounding structures of face, (3) osseous hyperplasia of subjacent bone, and (4) a high recurrence rate. We report a case of a nine-month-old infant who presented with swelling over right face since birth. Early diagnosis of this lesion provides better surgical approach to control the infiltrative nature of its growth with recurrence and aesthetic appearance.

Congenital diffuse infiltrating facial lipomatosis

Congenital diffuse infiltrating lipomatosis of the face (CDIL-F) is a rare pathological entity belonging to the subgroup of lipomatous tumors. Till date only a handful of cases has been documented and known to occur exclusively in infancy. On microscopical examination, it is characterized by diffuse infiltration of mature adipose tissue over normal muscle fibers, rapid growth, associated osseous hyperplasia, and a high recurrence rate after surgical intervention. An attempt has been made to identify and characterize all the 49 documented cases of CDIL-F in literature along with describing a report of a male child with CDIL-F. Follow-up of 8 years has been documented. The pathogenesis and spectrum of treatment modality are discussed with identified clinical features.

Idiopathic osseous hyperplasia of the nasal turbinates in a Welsh terrier

A three-year-old Welsh terrier was presented with a 6-month history of progressive stertor, exercise intolerance and sneezing which was unresponsive to symptomatic treatment. A large calcified mass occupying the entire rostral right nasal cavity was defined with computed tomography. The mass was completely removed via a dorsal rhinotomy. Histopathological examination of the mass revealed osseous hyperplasia of the nasal turbinates. The excision led to complete resolution of clinical signs and there has been no recurrence 18 months after surgery.

下顎に発生したＳｕｂｐｏｎｔｉｃ ｏｓｓｅｏｕｓ ｈｙｐｅｒｐｌａｓｉａの１例

We report on a 51-year-old man who had subpontic osseous hyperplasia (SOH) of the mandible.SOH is a rare variant of benign exostosis which occurs on the alveolar crest below the pontic of a fixed bridge prosthesis. The histopathologic characteristics of SOH closely resemble those of osteoma.The surgical specimen of the present case histopathologically showed well formed compact bone with lamellae and Haversian systems. Although a total of 59 cases of SOH have been reported, its cause has not been clarified. In our patient, SOH may have been induced by inflammatory stimulation due to periodontitis of the adjacent teeth.

下顎頭に生じた周辺性骨腫の１例

Osteoma is frequently found in the field of oral surgery. Although most osteomas occur in the maxillary sinus, the condylar head is a rare location for these lesions. The present report describes a case of condylar osteoma. A 47-year-old woman consulted the oral surgery clinic at Kanazawa University on Sept. 19, 1994. Her chief complaint was TMJ discomfort on chewing. Radiographic examination showed osseous hyperplasia at the left condyle. The lesion was resected under general anesthesia on Nov. 15, 1994. Histologic examination revealed that the lesion was an osteoma. The postoperative course was good. Three months after surgery, the patient could open her mouth more than 40mm without discomfort. However, careful follow-up is necessary.

Peripheral osteoma of the mandible: A study of 10 new cases and analysis of the literature

Ten new cases of peripheral osteoma of the mandible are described. These lesions are uncommon and only 15 other cases have been reported in the English language literature over the past 30 years. There is evidence to suggest that the peripheral osteoma of the mandible is a traumatically induced reactive lesion and that muscle traction plays a role in its initiation. In view of this possibility, the term “parosteal osseous hyperplasia” may be more appropriate for those lesions in which a positive history of trauma preceded the onset.

Nasal Toxicity of Chloroform in Male F-344 Rats and Female B6C3F1 Mice Following a 1-Week Inhalation Exposure

Chloroform is an important environmental water and air pollutant. Inhalation exposure of female B6C3F1 mice and F-344 rats for 6 hr/day for 7 consecutive days to 0, 1, 3, 10, 30, 100, or 300 ppm of chloroform resulted in concentration-dependent lesions in the nasal passages. Chloroform-induced changes included increased epithelial mucosubstances in the respiratory epithelium of the nasopharyngeal meatus, primarily in the rats. A complex set of responses was seen in specific regions of the ethmoid turbinates, predominantly in the rats. These lesions in the ethmoid region, which involved all of the endo- and ectoturbinates, were most severe peripherally and generally spared the tissue adjacent to the medial airways. These changes were characterized by atrophy of Bowman′s glands, increased numbers of vimentin-positive cells in the periosteum, new bone formation, and increased numbers of periosteal cells in S phase as determined by bromodeoxyuridine incorporation. Additional changes were site-specific loss of mucosubstances and loss of immunocytochemical staining of acini and ducts of Bowman′s glands for P450-2E1 and pancytokeratin, and loss of P450-2E1 immunostaining of the olfactory epithelium. The only change noted in the mice was increased cell proliferation without the osseous hyperplasia. The no-observed-effect level for these responses ranged from 3 to 100 ppm, with histological changes and induced cell proliferation being the most sensitive parameters. It is proposed that the osseous changes induced by chloroform exposure may be secondary to primary degeneration of adjacent Bowman′s glands. The relevance of these changes to human health risks include potential damage to the sense of smell, but such effects would not be expected at the low levels of chloroform commonly encountered in the environment.

The Toxicity of 1-Week Exposures to Inhaled Chloroform in Female B6C3F1 Mice and Male F-344 Rats

The Toxicity of 1-Week Exposures to Inhaled Chloroform in Female B6C3F1 Mice and Male F-344 Rats. Larson, J. L., Wolf, D. C., Morgan, K. T., Mery, S., and Butterworth, B. E. (1994). Fundam. Appl. Toxicol. 22, 431-446.Detailed quantitative descriptions of the toxicity of inhaled chloroform are lacking, despite the fact that the majority of environmental exposures occur by this route. We investigated the ability of chloroform vapors to produce toxicity and regenerative cell proliferation in the livers and kidneys, the principal target organs for carcinogenicity of female B6C3F1 mice and male F-344 rats, respectively. Nasal passages were also examined for toxic responses. Rodents were exposed to chloroform vapors at concentrations of 0, 1, 3, 10, 30, 100, or 300 ppm for 6 hr/day for 7 consecutive days and necropsied on Day 8. Animals were administered bromodeoxyuridine (BrdU) via implanted osmotic pump for the previous 3.5 days before necropsy. Cell proliferation was quantitated as the percentage of cells in S-phase (labeling index; LI) measured by immunohistochemical detection of BrdU-labeled nuclei. Mice exposed to 100 or 300 ppm exhibited centrilobular hepatocyte necrosis and severe vacuolar degeneration of midzonal and periportal hepatocytes, while exposure to 10 or 30 ppm resulted in mild to moderate vacuolar changes in centrilobular hepatocytes. Slight, dose-related increases in the hepatocyte LI were observed for exposure concentrations of 10 and 30 ppm, while the LI was increased more than 30-fold in the 100 and 300 ppm groups. The kidneys of mice were affected only at the 300 ppm exposure, with approximately half of the proximal tubules lined by regenerating epithelium and an increased LI of tubule cells of 8-fold over control. In rats, mild centrilobular vacuolation was observed only in the livers of rats exposed to 300 ppm. The hepatocyte LI in rats were increased only at 100 and 300 ppm, 3- and 7-fold over control, respectively. In the kidneys of the male rats exposed to 300 ppm, about 25 to 50% of the proximal tubules were lined by regenerating epithelium. The LI for tubule cells in the cortex was increased at 30 ppm and above. In the nasal passages of rats, chloroform concentrations of 10 ppm and above induced histopathological changes that exhibited clear concentration-related severity. These lesions consisted of respiratory epithelial goblet cell hyperplasia and degeneration of Bowman's glands in olfactory mucosa with an associated osseous hyperplasia of the endoand ectoturbinates in the periphery of the ethmoid region. These nasal lesions were not observed in mice. Knowledge of the dose-dependent responses in rats and mice will be valuable in assessing the potential risks to humans posed by inhaled chloroform and in setting exposure concentrations for longer-term studies.

Diagnosis and treatment of subpontic osseous hyperplasia: Report of a case

This report describes a case of subpontic osseous hyperplasia that occurred in the posterior mandible of a healthy 67-year-old woman. The two hard masses, which were removed from beneath a fixed partial denture that was placed 35 years ago and spanned the lower left first premolar and the first and second molars, consisted of normal viable dense cortical bone. Only 30 cases of this phenomenon defined as a slow-growing, benign osseous proliferation occurring on the crest of the alveolar ridge beneath the pontic of a fixed partial denture have been described in the literature. Possible causes, including genetic programming, functional stimulus, and mild chronic irritation are discussed, as well as rationale for treatment of this anomaly.

Investigating Incidental Remission of Subpontic Hyperostosis

Removing a fixed partial denture may be an option as valid as surgery to treat patients who have subpontic osseous hyperplasia.

Subpontic osseous hyperplasia: A literature review

Several incidences of excessive bone growth beneath the pontics of posterior fixed partial dentures have been documented, and this phenomenon has been referred to as subpontic osseous hyperplasia. The clinical, radiographic, and microscopic features are discussed, including the presentation of several etiologies and treatment considerations.

A case report of osseous hyperplasia under the pontic.

A case report of osseous hyperplasia under the pontic.