In addressing the design challenges for constant-stress accelerated life testing in non-rectangular experimental domains, we aim to optimize the precision in estimating parameters for the product reliability statistical model. Following the principles of regression orthogonal design theory to determine the combinations of stress levels, we constrain the maximum stress levels of each experimental stress along the boundary curve of the non-rectangular experimental domain. The remaining stress levels and the allocation ratios of specimens for each test serve as design variables in the optimization process. We establish a mathematical model for the optimal design of constant-stress accelerated life testing in non-rectangular experimental domains. The results of the optimized design for comprehensive stress accelerated life testing in non-rectangular experimental regions of aerospace electrical connectors indicate that, with the same sample size, the optimized testing scheme not only enhances the precision of model parameter estimation but also reduces the number of required tests. At an equivalent number of tests and testing duration, the optimization scheme proposed in this study demonstrates an improvement of over 63% in the precision of model parameter estimation compared to the EM-optimized testing scheme in non-rectangular experimental regions. Using the mean, standard deviation, and coefficient of variation of the determinant values of the information matrix as criteria for evaluating the precision and robustness of experimental designs, a simulated evaluation was conducted for the optimized experimental design, a conventional experimental design, and an EM experimental design. The results indicate that the optimal experimental design outperforms both the conventional experimental design and the EM experimental design in terms of precision and robustness.
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