This study had two major objectives: to assess the effect of nutrition education carried out among urban and peri-urban farming communities in Kampala, Uganda on (a) production of Orange-Fleshed Sweet Potato (OFSP), and (b) vitamin A related knowledge, attitudes and practices of child caregivers. A Cross-sectional sample of households that were involved in farming of orange fleshed sweet potato (OFSP) and had 2–6 year old children (n=457) were purposively selected from four divisions of Kampala Capital City Authority (Kawempe, Rubaga, Makindye, and Nakawa) to participate in a controlled, cohort intervention. Respondents in Kawempe division had received training in production of OFSP and nutrition education; Rubaga division only had training in production of OFSP; Nakawa division only had nutrition education while Makindye division did not have any training and served as the control. A coded questionnaire was used to collect caregiver’s perceptions of nutrition and production attributes of OFSP compared with other potato varieties as well as Vitamin A related knowledge, attitudes and practices. Chi-square tests were used to test for relationships amongst divisions for variables of interest. A p value of < 5% was used to judge statistically significant differences. Results showed that all respondents judged OFSP varieties to be better than other potato varieties with respect to: early maturity, yield, multiple utilization, nutritional value, and taste (p<0.05). Respondents who had received nutrition education had better knowledge than other respondents related to vitamin A, OFSP as a source of vitamin A and attitudes towards health and child health practices (p<0.05). About 60% of the respondents that received nutrition education correctly identified at least two sources of vitamin A compared to about 40% for respondents without nutrition education. Results from a seven (7) day recall showed significantly higher consumption of foods that are rich in Vitamin A by respondents from divisions that received nutrition education (p<0.05). Similarly, significantly more respondents who had nutrition education had positive attitudes toward Vitamin A utilization.