Oral Symptoms Research Articles

The Relationship Between Depression, Anxiety and Oral Symptom in Adults According to Mask-wearing During the COVID-19 Pandemic

The Relationship Between Depression, Anxiety and Oral Symptom in Adults According to Mask-wearing During the COVID-19 Pandemic

The effects of mental health-related factors on experience of oral symptoms in high school students

The effects of mental health-related factors on experience of oral symptoms in high school students

자활참여 근로자의 정신건강 수준과 구강 증상의 관련성에 관한 연구

Objectives: This study was conducted to examine the mental health of self-supporting workers and to verify their relationship with oral symptoms.
 Methods: The research was conducted from November 1, 2021 to January 30, 2022, and included 691 self-supporting personnel working in local self-sufficiency centers. Items related to depression, insomnia, anxiety, somatic symptoms, and oral symptoms were investigated. The data were analyzed with the chi-square test and logistic regression, using IBM SPSS version 25 software.
 Results: The level of depression was 5.92 times higher than moderate severe and level of somatic symptoms was 10.96 times higher than severe with dry mouth having the highest level. Insomnia was 4.28 times higher than severe the anxiety level was 5.04 times higher than severe and toothache had the highest level.
 Conclusions: Follow-up research on the oral symptoms of self-supporting workers belonging to the mental health risk group is needed. Establishment of an oral health status condition for self-supporting workers is also necessary

Evaluation of Oral Findings, Symptoms, and Parental Satisfaction of Pediatric Patients Whose Dental Rehabilitation Was Completed with General Anesthesia

Evaluation of Oral Findings, Symptoms, and Parental Satisfaction of Pediatric Patients Whose Dental Rehabilitation Was Completed with General Anesthesia

Nutrition and oral health in children with recently and previously diagnosed celiac disease.

To evaluate the nutritional and oral health status of children with previously diagnosed celiac disease (CD) who follow a gluten-free diet and recently diagnosed CD patients. Previously and recently diagnosed groups were formed from children with CD, aged 4 to 15 years. A questionnaire was completed about the children's dental history and nutritional and oral hygiene habits. All the children underwent an oral examination, and dmft-DMFT indices were determined. Dental plaque status, periodontal health, and dental enamel defects were recorded. Oral soft tissues were examined for the presence of lesions. Unstimulated salivary flow rate and pH value were evaluated. A statistically significant difference was determined between the previously and recently diagnosed patients in terms of toothpaste preference (p=0.003), frequency of going to the dentist (p=0.039), and the types of dental treatment they had received (p=0.001). A statistically significant difference was determined between the previously and recently diagnosed patient groups in terms of dmft values (p=0.005). Children with CD should be directed to a pediatric dentist to improve oral and dental health, relieve the symptoms of oral mucosal lesions, be informed about enamel defects, and be encouraged to use gluten-free oral care products. The collaboration of pediatric gastroenterologists and pediatric dentists can prevent the progression of oral symptoms in children with CD and eliminate long-term complications in terms of both oral health and multisystemic problems.

Oral candidiasis in a specialist palliative care unit: assessment, diagnosis, management

ObjectivesTo evaluate current clinical practices of assessment, diagnosis and management of oral candidiasis in a specialist palliative care unit to improve patient outcomes through compliance with the Australian Commission on...

A Systematic Review and Meta-analysis of the Initial Literature Regarding COVID-19 Symptoms in Children in the United States

COVID-19 symptom presentation among adults is mostly understood. However, understanding COVID-19 symptom presentation in children lags. A literature search was conducted in three electronic databases. Twenty-three initial publications addressing COVID-19 symptom presentation among hospitalized children in the United States met the criteria for review and meta-analysis. Fever, the most common symptom, was present in nearly all cases. Gastrointestinal, respiratory, oral symptoms, and rash occurred in over half of the cases. Disease severity assessment showed that comorbidities were present in one-third of patients; intensive care was needed for half of the patients, and supplemental oxygen and mechanical ventilation were needed by 13.3% and 7.1%, respectively. The magnitude and significance of COVID-19 symptoms in children compared with those in adults and three common childhood viral illnesses: influenza, respiratory syncytial virus, and gastroenteritis, are discussed. Important clinical differences were found that may help clinicians distinguish COVID-19 from other illnesses.

Burning mouth syndrome: Analysis of diagnostic delay in 500 patients.

To assess the diagnostic delay, the number and type of referrals and the clinical and psychological profile in a wide sample of patients with Burning Mouth Syndrome (BMS). Data on the disease onset, oral symptoms, type and number of practitioners consulted, misdiagnoses, and the presence of medically unexplained extraoral physical symptoms were recorded in 500 BMS patients. Potential predictors of diagnostic delay were also evaluated. The mean diagnostic delay was 29.71 ± 47.19months. An average of 2.61 ± 1.65 practitioners were consulted by each patient, the most frequent being the general physicians (287; 57.4%), maxillofacial surgeons (111; 22.2%), and otolaryngologists (104; 20.8%). The mean number of misdiagnoses was 3.54 ± 1.85. Nonspecific stomatitis, candidiasis, and gastroesophageal reflux were the most common misdiagnoses. Higher age, low education, the presence of dysgeusia, and a previous history of psychiatric illness were predictors of a longer diagnostic delay (p-value: 0.028, 0.050, 0.007, 0.034, respectively). The lack of knowledge among specialists, the high rate of misdiagnosis, and the diagnostic delay of BMS highlight the need to introduce educational interventions in all medical specialties in order to promote an early and appropriate diagnosis, thereby improving the prognosis and quality of life of the patients.

Detection of SARS-CoV-2 IgG antibodies and inflammatory cytokines in saliva-a pilot study.

The pandemic caused by SARS-CoV-2 virus continues to have a profound effect worldwide. However, COVID-19 induced oral facial manifestations have not been fully described. We conducted a prospective study to demonstrate feasibility of anti-SARS-CoV-2 IgG and inflammatory cytokine detection in saliva. Our primary objective was to determine whether COVID-19 PCR positive patients with xerostomia or loss of taste had altered serum or saliva cytokine levels compared to COVID-19 PCR positive patients without those oral symptoms. Our secondary objective was to determine the correlation between serum and saliva COVID-19 antibody levels. For cytokine analysis, saliva and serum were obtained from 17 participants with PCR-confirmed COVID-19 infection at three sequential time points, yielding 48 saliva samples and 19 paired saliva-serum samples from 14 of the 17 patients. For COVID-19 antibody analyses, an additional 27 paired saliva-serum samples from 22 patients were purchased. The saliva antibody assay had 88.64% sensitivity [95% Confidence Interval (CI) 75.44%, 96.21%] to detect SARS-CoV-2 IgG antibodies compared to serum antibody. Among the inflammatory cytokines assessed - IL-6, TNF-α, IFN-γ, IL-10, IL-12p70, IL-1β, IL-8, IL-13, IL-2, IL-5, IL-7 and IL-17A, xerostomia correlated with lower levels of saliva IL-2 and TNF-α, and elevated levels of serum IL-12p70 and IL-10 (p<0.05). Loss of taste was observed in patients with elevated serum IL-8 (p<0.05). Further studies are needed to construct a robust saliva-based COVID-19 assay to assess antibody and inflammatory cytokine response, which has potential utility as a non-invasive monitoring modality during COVID-19 convalescence.

How important is patch testing with dental materials in real-life clinical practice?

Background: Allergy to dental materials in prostheses and implants that leads to dental device dysfunction is a challenging problem. Objective: In this prospective study, we aimed to investigate the diagnostic role and impact of dental patch test (DPT) results on the outcome of proceeding dental procedures with the collaboration of our allergy clinic and dental clinics. Methods: A total of 382 adult patients with oral or systemic signs or symptoms due to the applied dental materials were included. A DPT with 31 items was administered. The clinical findings after dental restoration according to the test results were assessed in the patients. Results: The most common positivity detected in the DPT was due to metals, among which nickel (29.1%) was the leading cause. The frequency of self-reported allergic diseases and metal allergy was significantly higher in patients with at least one positive result in the DPT (p = 0.004 and p < 0.001, respectively). Clinical improvement after the removal of dental restoration was seen in 82% of the patients who had a positive DPT result, whereas this rate was 54% among paatients with negative DPT results (p < 0.001). The only factor that predicted improvement after restoration was the positivity in the DPT result (odds ratio 3.96 [95% confidence interval, 0.21-7.09]; p < 0.001). Conclusion: Our study showed that a self-reported metal allergy was an important finding to predict allergic reactions to dental devices. Therefore, patients should be questioned for the presence of metal allergy-related signs and symptoms before exposure to the dental materials to prevent possible allergic reactions. Furthermore, DPT results are valuable to guide dental procedures in real life.

Illness perception amongst individuals with periodontal diseases.

To describe illness perception among patients with periodontal diseases in relation to socio-demographic predictors, oral signs and symptoms. Cross-sectional analytical study. Stratified quota sample of 353 consecutive adults with periodontal diseases attending university dental clinics in Iran. The illness perception of periodontal diseases measured using the Brief-Illness Perception Questionnaire. Participants' mean age was 38.7 years and 53% were female. The most frequent symptoms were tooth sensitivity, inflamed and painful gingiva, and halitosis. The symptoms that participants associated with periodontal diseases were inflamed and painful gingiva, bleeding while brushing, flossing or eating, and gingival recession. Illness perception was associated with education level, the patient's experience of periodontal symptoms, individuals' attitudes about an association between oral signs and symptoms with periodontal diseases and clinical attachment loss. Understanding how patients perceive their disease is a crucial step to motivating and engaging them in periodontal therapy and in the healthcare process.

The Mediating Effect of Perceived Oral Symptoms on the Relationship between Oral Health Beliefs and Oral Health-related Quality of Life of Hotel Workers

The Mediating Effect of Perceived Oral Symptoms on the Relationship between Oral Health Beliefs and Oral Health-related Quality of Life of Hotel Workers

Oral Manifestations Associated with COVID-19 Infection: A Cross-Sectional Study of Recovered Iraqi Patients.

The aim of this study was to determine prevalence of oral manifestations related to COVID-19 infection among a sample of recovered patients in the Basrah province of Iraq. Methodology. This cross-sectional study included a total of 574 individuals from Basrah city, Iraq (196 males and 378 females), who had been previously infected with COVID-19. A questionnaire was developed and used to record the demographic data, medical history, severity of respiratory infection followed by hospitalization along with oral signs and symptoms that occurred during the COVID-19 infection and their persistence after recovery. Oral manifestations were reported in 88.3% of the studied sample. The most common oral manifestation was ageusia (66.8%), followed by dry mouth (59%), gustatory changes (46%), dysphagia (40.5%), burning sensation (20.8%), oral ulceration (14.5%), and gingival bleeding (3.3%). The findings suggested that ageusia was the only symptom that persisted following recovery from the COVID-19 infection. The results showed a significant statistical correlation between the incidence of oral manifestations and the severity of COVID-19 infection followed by hospitalization. A significant correlation was also found between the age groups and COVID-19 oral manifestations, whereas no significant statistical relationship was observed between gender, smoking, and systemic diseases. COVID-19 infection has considerable impacts on the oral cavity and salivary glands and after recovery from the infection, some patients continue to complain of ageusia for several months. There is a positive correlation between the incidence of oral signs and symptoms associated with COVID-19 infection and the severity of the infection.

COVID-19 Vaccine Survey: Post Vaccine Complications Including Oral Manifestations

BACKGROUND: The deadly pandemic began in November 2019 in Wuhan, Republic of China, has been a life altering event in the history of the Earth. Literature has suggested that a primary series plus booster doses of mRNA vaccine shows modest to high effectiveness against severe COVID-19 outcomes, including hospitalization, mechanical ventilation, and death also effectively prevents symptomatic infection. AIM: To evaluate the post vaccination complications faced by people, with primary focus on oral manifestations after vaccination. MATERIALS AND METHOD: The present study is a cross-sectional, questionnaire descriptive study, carried out from May 2021 to January 2022 to evaluate the public’s knowledge, attitudes, and practices during the COVID-19 epidemic using an anonymous online questionnaire. The survey was conducted via an online platform. RESULTS: Changes in sensitivity were reported by 2.7% and 3.1% of the sample after the first and second dose, respectively. Oral symptoms were reported by 3.1% and 4% of the respondents after the first and second dose. Among the oral manifestations, dry mouth was the most frequent OAE after both the first and second doses. CONCLUSION: Based on the results of this preliminary survey, there is no observed significant correlation between vaccine administration for COVID-19 and facial and oral manifestation. Complications and vaccinations on apprehensions were significantly associated COVID-19 related psychological impacts that were studied.

Association between Asthma and Oral Health Symptoms in Adolescents.

Oral health is an indicator of patients' overall quality of life. Poor oral health among adolescents with asthma can affect their health in adulthood. This study researched the association between asthma and oral health symptoms in South Korean adolescents. Data from the 2020 Korea Youth Risk Behavior Web-based Survey were used. A total of 44,940 students participated in this study. The dependent variables were self-reported oral health symptoms. Asthma was the primary independent variable based on diagnosis in the past 12 months. The chi-squared test and multivariable logistic regression analysis were used. Students with asthma were associated with oral health symptoms, compared with those without asthma (boys, odds ratio (OR): 1.29, 95% confidence interval (CI) = 1.01-1.66; girls, OR: 1.94, 95% CI = 1.40-2.69). Poor health habits, such as low physical activity, higher sweetened beverage consumption, and fewer sleeping hours, were associated with oral health symptoms. Students who did not receive asthma treatment also had higher oral health symptoms (boys, OR: 1.29, 95% CI = 1.13-1.48, girls, OR: 1.34, 95% CI = 1.15-1.57). Students with absence due to asthma had a higher risk of oral health than those without asthma (boys, OR: 1.31, 95% CI = 1.17-1.46, girls OR: 1.28, 95% CI = 1.12-1.46). Students with asthma had a high risk of poor oral health among South Korean adolescents, suggesting more attention be given to regular dental check-ups and maintaining oral hygiene.

Effect of the coronavirus disease 2019 pandemic on oral health of Korean adolescents.

To investigate the effect of the coronavirus disease (COVID-19) pandemic on Korean adolescents' oral health and identify the influential factors. The raw data from The Korea Youth Risk Behaviour Web-based Survey before (2019) and after (2020) the outbreak of COVID-19 were used in the study. Demographic characteristics and subjective general, mental, and oral health were analysed and compared between the 2 years. Further, the impact of changes in subjective mental health and the duration of indoor activity on oral health were analysed. Data were analysed using IBM SPSS Statistics, and all statistical significance was set at α=0.05. The analysis was performed using the complex sample analysis module. In 2020, compared with 2019, the proportion of adolescents who rated high on subjective academic performance, smoking, and drinking decreased (p < 0.001). However, there was no difference in the household economic status between 2020 and 2019 (p=0.917), while subjective mental health improved. In addition, the risk of tooth fracture was 1.321 times higher after the pandemic. After the outbreak of COVID-19, adolescents who were indoors for >24 h for non-learning activities on weekends were 2.97 times more likely to have reported gingival pain and bleeding (p < 0.05). After the outbreak of COVID-19, smoking and drinking decreased in Korean adolescents, while changes occurred in their learning patterns at home, and their mental health improved. Some oral symptoms increased or showed no change.

The relationship between subjective oral frailty and adverse health outcomes or medical and dental expenditures in the latter-stage older adult: A 6-year longitudinal study.

The study aimed to investigate the relationship between subjective oral frailty and adverse health outcomes or medical and dental expenditures in the latter-stage older adult through a 6-year longitudinal study. The participants enrolled in the cross-sectional study were 3564 Tokushima City residents aged 75, 80, 85, and 90 years old who received oral health examinations and who responded to a questionnaire on oral conditions and health behavior at baseline. The data forthe occurrence of disability or mortality, and the monthly medical expenditures, dental expenditures, and total medical expenditure of each participant were obtained from the National Health Insurance Database. The total medical expenditure showed significant differences in participants who had difficulties in eating tough foods, difficulties in swallowing tea or soup, and dry mouth when compared to that of healthy participants, in addition to the current medical treatment against the general disease. The 6-year longitudinal study revealed that participants with subjective oral frailty symptoms, including difficulties in eating tough foods and difficulties in swallowing tea or soup at baseline, had significantly higher medical, dental, and total expenditures among 538 participants without certified nursing care. In addition, those with subjective oral frailty or with less than 19 teeth present were shown to have a higher possibility for the occurrence of disability or mortality by the cox proportional hazard analysis. Furthermore, it was found that medical and total expenditures in older adults with adverse health outcomes were higher than that of healthy participants. These results suggest that subjective oral frailty in the latter-stage older adult is related to subsequent adverse health outcomes and an increase in medical and dental expenditures.

Spotting the signs

Preetee Hylton reminds us of the key oral STI symptoms to keep an eye out for, and how to have a safe Valentine's day!

On a pathway to resigned acceptance: Patients' experiences of living with symptom clusters in oral cancer.

Patients treated for oral cancer experience multiple concurrent symptoms. A larger mixed-methods study was conducted among patients who were treated with surgery alone or in combination with other modalities. The aim of the qualitative strand was to explore the experiences of living with symptom clusters. A phenomenological design was used to explore the lived experiences. Participants were recruited for the larger study from two outpatient units of a tertiary teaching hospital (N=300). After completion of a survey, a maximum variation purposive subsample of 20 participants was drawn from the larger sample and were interviewed in-depth about their experiences. Thematic analysis was conducted. All participants experienced multiple concurrent symptoms, commonly including chewing difficulties+dry mouth+speech difficulties; chewing difficulties+dry mouth+diminished taste; and chewing difficulties+dry mouth+speech difficulties+trismus. Analysis of their experiences of living with these symptom clusters revealed six themes: Acknowledged Disruptions, Inner Dialogue, Shifting Expectations, Floods of Emotions, Exercising Control over Life, and Resigned Acceptance. These themes portrayed that time and living with symptom clusters lead to what we describe as a pathway to resigned acceptance. This pathway is intermingled with disruptions, self-reflections on 'why me' and karma, negative emotions, and failed expectations regarding symptom recovery. Attempts to exercise control over their lives were also revealed through coping strategies, watchful living, future planning, and being health advocates. On realizing with time that further symptom alleviation is unlikely, and considering symptom-cluster experiences as being written in their fate, they move towards a state of resigned acceptance. However, unlike passive acceptance, their belief in fate was accompanied with resilience, evidenced by their ongoing efforts to explore pragmatic ways to live with symptom clusters. Findings provide key insights into patient perspectives which most often remain unexpressed in clinical settings. Further research is required to explore watchful living, fate as a coping strategy, and intertwining of faith, fate, and karma.

Drug induced stomatitis medicamentosa: Report of a rare case

Oral medicine is a specialty that deals with the diagnosis and treatment of complex medical diseases of the oral mucosa. Successful treatment depends on a proper and accurate diagnosis. A successful diagnostician must possess qualities such as knowledge, interest, intuition, curiosity, and perseverance. His 99.9% of systemic illnesses have one or more of his oral symptoms diagnosed by an oral health professional before a general practitioner. Early detection and diagnosis are critical for early treatment, improved survival, and limited treatment complications. We present the case of a 14-year-old female who had an acute oral allergic reaction to an over-the-counter drug.