109 Background: Despite advances, challenges remain in the early detection and management of oral cancers. Studies have indicated that worse outcomes can be linked to disparities in sex, race, and ethnicity. Research indicates that despite a greater incidence of oral cancer among White patients, the five-year survival rate for Black patients is 52%, compared to 70% for their counterparts (1). While existing research focuses on racial and ethnic disparities in the time to diagnosis and prognosis, there is limited literature that discusses disparities in time to treat. As such, our study aims to evaluate potential racial, ethnic, and/or gender disparities in the time between diagnosis and surgery. Methods: We conducted a retrospective cohort study evaluating 185 patients with oral cancer at the University of Miami. Patient information was obtained from electronic medical records. We performed analysis of variance (ANOVA) with post hoc tests. Levene's test was used to assess the homogeneity of variances assumption. All statistical analyses were performed using SPSS version 26.0 (IBM Corp., Armonk, NY, USA), and p-values less than 0.05 were considered statistically significant. Results: The mean age at diagnosis was 68.50 years (SD =13.079 years), with the majority of patients (42%) diagnosed as Stage 1. Our cohort was 46% female and 54% male. 62% identified as White and Non-Hispanic/Latinx, 29% as White and Hispanic/Latinx, 6% as Black, and 3% as other race/ethnicities. We also assessed time to treat as a function of gender, race and ethnicity. We found there was no significant difference between men and women (x̄= 148 vs 136 days) in time to surgery. We also found no difference between Hispanic/Latinx patients and non Hispanic/Latinx patients (x̄= 163 vs 137 days). Although not statistically significant, there was a notable trend in the data that showed a longer time to surgery. Black patients had a much greater time to surgical intervention compared to White patients (x̄= 308 days vs 134 days) (Table). At the time of data cutoff, nearly 81% of patients were alive. Conclusions: In conclusion, despite lack of statistical significant, our study found higher trends to time to surgery between Hispanic/Latinx and non-Hispanic/Latinx, and even more so a much greater difference in time to surgery between Black and White patients. Further research is needed to elucidate these potential systematic, socio-economic or cultural barriers to ensure equitable access. 1. Surveillance, Epidemiology, and End Results (SEER) Program, National Cancer Institute. Days between diagnosis and surgery. Ethnicity Mean Standard Deviation N Black or African American 308.44 737.375 9 Other 20.33 .577 3 White 134.37 467.579 147 Total 142.08 481.112 159