This study evaluates the feasibility of using pretreated domestic wastewater (PDW) for food production in a hydroponic system. In the face of increasing water shortage problems and rising fertilizer costs, PDW combined with a limited amount of fertilizer is evaluated for its effects on plant growth, biomass yield, and product safety. The results showed that lettuce grown with PDW and mineral fertilizers reached a fresh weight of 116, while the use of organic fertilizers increased the yield to 127 g, compared to only 54 g with raw water. Nitrate concentration (NO3) was higher in lettuce grown with organic fertilizers (1044.33 ± 144.04 mg/kg) than with mineral fertilizers (623.33 ± 85.62 mg/kg), but the values remained well below the acceptable limit of 5000 mg/kg for safe consumption. Analysis of heavy metals confirmed that levels of arsenic, cadmium, mercury, and lead were significantly lower than the maximum permissible values set by FAO and EU regulations. In addition, no phthalates were detected in the lettuce biomass, confirming the safety of the materials used in the hydroponic system. The use of PDW in hydroponic crops significantly reduces dependence on potable water and synthetic fertilizers, contributing to sustainable resource management. This approach not only reduces production costs, but also reduces the water footprint of crops, which is crucial in the context of global water availability problems. The findings support the validity of using PDW in decentralized food production as a sustainable solution for regions facing water and fertilizer shortages. Further research will focus on optimizing nutrient management and environmental conditions to increase system efficiency and food safety.
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