PurposeThe Chinese believe that “man will conquer the sky” and “fighting with the sky brings endless joy”. Considering that disaster assessment can be regarded as a two-person, zero-sum game problem between nature and human beings, this paper proposes a multi-attribute decision-making method based on game theory and grey theory in a single-value neutrosophic set environment. Due to the complexity and uncertainty of the decision-making environment, the method builds a decision matrix based on single-valued neutrosophic numbers.Design/methodology/approachFirst, the authors use the single-value neutrosophic information entropy to calculate the attribute weights and the weighted decision matrix. Second, the optimal mixed strategy method based on linear programming solves the optimal mixed strategy for both sides of the game so that the expected payoff matrix can be obtained. Finally, grey correlation analysis is used to obtain the closeness coefficient of each alternative based on the expectation payoff matrix to identify the ranking result of the alternative.FindingsAn example is used to verify the effectiveness of the proposed method, and its rationality is verified through a comprehensive comparison and analysis of the various aspects.Practical implicationsThe proposed decision-making method can be applied to typhoon disaster assessment. Such assessment results can provide intelligent decision support to the relevant disaster management departments, thereby reducing the negative impact of typhoon disasters on society, stabilizing society and improving people's happiness. Further, the method can be used for decision-making, recommendation and evaluation in other fields.Originality/valueThe proposed method uses single-value neutrosophic numbers to solve the information representation problem of decision-making in a complex environment. Under a new perspective, game theory is used to handle the decision matrix, while grey relational analysis converts inexact numbers to exact numbers for comparison and sorting. Thus, the proposed method can be used to make reasonable decisions while preserving information to the extent possible.