One hundred years later, dearly missed Arnaldo Vieira de Carvalho’s advice continues to serve as an encouragement for the current generations to pursue with competence, dedication and passion the perpetuation of Revista de Medicina as a dissemination vehicle of scientific results obtained by the students of USP School of Medicine (Faculdade de Medicina da USP – FMUSP) and all over the country, seeking to adapt it to the innovation and modernities of our Era. In this article, I will not focus on historical aspects, so brilliantly addressed by Gustavo Gameiro in the Editorial as well as by Cyro Festa and Andre Mota in the previous article, but I will aim to demonstrate, using the recent advances of Revista de Medicina in scientific and management terms, the reasons for my optimism regarding the future of this journal and its prospects. From the scientific point of view, Revista de Medicina aims to provide the dissemination of medical students’ results and scientific activities, giving them visibility in the medical literature. Throughout these 100 years, many current researchers had their first papers published by Revista de Medicina while they were still students. Through periodic and thematic issues, the journal features not only articles written primarily by medical students, but also systematic reviews conducted by renowned Researchers, who are invited to write for special issues of the journal. This quality policy associated to the availability of digital versions of the journal, reducing its cost of publication and distribution also allowed the journal to be even more distributed. A unique data revealing the relevance and scope of this space is the fact that Revista de Medicina is in the leading position of scientific papers downloads among the journals listed in the USP Portal of Journals (Portal de Revistas da USP), the largest in Latin America. Combining the opportunity of publishing for students still in college with the search for quality and scientific standards is a delicate and balanced work, performed by the journal’s Board of Directors with the support of the scientific editorial board, responsible for the “peer review”of the papers. This Editorial Board, formerly comprising exclusively FMUSP full Professors and Professors Emeriti, was considerably redesigned and started performing the Advisory Board function since 2014, featuring now 31 members, Including USP faculty and Researchers connected to the Hospital das