Course Of Operation Research Articles

ОСОБЛИВОСТІ ІДЕНТИФІКАЦІЇ ТОВАРІВ ПРИ ЗДІЙСНЕННІ ЕКСПОРТНО-ІМПОРТНИХ ОПЕРАЦІЙ

In the course of export and import operations, the identification of goods plays an important role in ensuring the correct execution of customs declarations, compliance with customs regulations, and determining the rate of customs duties and other payments. Identification is a preliminary stage of the classification of goods and is important in shaping the flow of goods, accelerating customs procedures and improving their efficiency. It should be noted that a purely commodity-based approach to the classification of goods will be somewhat different from the customs approach, as the customs approach must adhere to the basic rules of interpretation of the explanations, exceptions and notes to sections and groups, terminology, and must take into account the properties, signs, indicators and methods of determination that are accepted as determinative and recommended when identifying classification groups. Despite the existence of many scientific works on the topic of this study, the essence of identification as a component of the process of export-import operations in Ukraine has not yet been clarified, aspects of the current state of functioning have not been identified, and ways of modernisation and means of identification of goods in export-import operations have not been proposed. The purpose of this study is to analyse the current state of affairs and to provide recommendations on how to create effective and reliable procedures for the identification of goods in order to improve export-import operations and ensure compliance with legislation and technical regulations. Thus, the identification of goods in the course of export-import operations is a set of actions of customs officials aimed at controlling the information on the customs value of goods transported across the customs border of Ukraine, with mandatory verification of accompanying documents for such goods and information on the counterparties to foreign economic transactions under which certain export-import operations were carried out.

Teaching posterior composite restorations: A survey of dental schools in Palestine

AimThis study aimed to assess different aspects of teaching posterior composite restorations in two dental schools in Palestine. Materials and methodsA questionnaire was emailed to the heads of the operative and conservative dentistry departments to collect detailed information on the teaching practices related to posterior composite restorations. The questionnaire comprised 22 questions structured to collect information on the time dedicated to teaching the topic, competency assessments, future plans for allocating time for each restoration type, relevant indications and contraindications, specific materials and techniques utilized in the application, and fees charged for posterior restorations. The gathered responses were collated in Excel and analyzed. ResultsBoth dental schools allocated similar teaching times to posterior composites and amalgam in their preclinical operative dentistry courses. However, there was a greater emphasis on composites in the clinical course than in the preclinical course at both institutions. Despite these differences, both institutions expressed a shared intention to allocate more time to teaching posterior composites while reducing the emphasis on teaching amalgam procedures. Consistency was observed across competency testing, cavity design preferences, and contraindications, with both schools favoring slot-type cavities. Furthermore, uniformity was noted in the management of operatively exposed dentin and matrix techniques, although variations existed in moisture isolation. Notably, both schools taught circumferential and sectional metal matrices but did not teach clear sectional matrices or use of bulk-fill composites. Additionally, the adhesive and light-curing practices remained consistent across both institutions. ConclusionThe findings of this study indicate that the teaching of posterior composite restorations is consistent across both Palestinian dental schools. Their curricula are aligned with contemporary international practices, demonstrating a strong commitment to modern operative dentistry and adherence to global standards. These findings offer valuable insights for educators and researchers and emphasize the need for ongoing adaptations to maintain high clinical standards.

Research on Teaching Practice of Big Data Platform Deployment and Operation Course with Shipping Characteristics

In the era of big data, big data technology has been widely applied, and the operation and maintenance of big data platforms, as a crucial component supporting these applications, has gradually become an indispensable part of enterprise IT architecture. The demand for talents with big data platform operation and maintenance skills is increasing. For higher vocational education institutions, how to cultivate big data platform operation and maintenance talents that meet professional requirements has become an urgent problem to be solved. In order to satisfy the enterprise demand for big data platform operation and maintenance talents and enhance students' employment competitiveness, this paper discusses the teaching content and teaching organization practice of the "Big Data Platform Deployment and Operation" course. The course adopts a project-based teaching mode, integrating the project case of "Ship Shore Power Data Analysis System" into the theoretical knowledge and technical explanations at various stages of the course. At the same time, it deeply excavates the ideological and political elements of maritime power and green environmental protection contained in the project, constructs a teaching mode with obvious shipping characteristics, and improves the quality of talent cultivation.

Spectrum of exploratory laparotomy for acute abdomen in a central Gujarat tertiary care centre

Background: Exploratory laparotomy is one of commonest emergency surgeries performed in the world. Despite technological advance imaging, the fundamental technique of exploratory laparotomy has remained unchanged over years. Studies quantifying the spectrum of laparotomy in central Gujarat are lacking. Methods: A retrospective study of 249 patients of emergency exploratory laparotomy for acute abdomen in SSG Hospital Baroda from May 2022 to May 2024 was done and data involving clinical presentation, imaging, operative findings and post- operative course were studied and analysed. The cases were divided into gastro-intestinal perforation, gastro-intestinal obstruction and miscellaneous cause. Results: The most common cause of exploratory laparotomy in study was perforation peritonitis including 59 ileal, 16 jejunal, 49 pre-pyloric, 29 duodenal, 1 body of stomach, 17 appendicular and 8 colon. With post op major complications like burst-11%, leak-5%, pneumonia-5%, multi-organ failure-6.5% and ileus 5%, wound infection 18%. The overall mortality was 15%. Out of 58 cases of laparotomy for obstruction including adhesions (29.3%), obstructed inguinal hernia (12%), tuberculosis (32%), malignancy (13.8%), internal hernia (12.6%). The miscellaneous causes were ruptured liver abscess (9), rupture ectopic pregnancy (2), twisted ovarian tumour (1). Conclusions: Acute abdomen remains a significant surgical problem. Peptic perforation remains a common cause of acute abdomen with high morbidity and mortality, despite improves medical management, though there is a declining trend in incidence, tuberculosis remains an important cause.

Strategies for Effective Product Roadmap Development and Execution in Data Analytics Platforms

Manufacturing is only one of several industries going through a digital transformation in this era of digital disruption. Manufacturing businesses are racing to adopt IoT-based solutions in order to innovate, increase productivity, lower costs, and gain greater market share because of the enormous transformational potential offered by Internet-of-Things (IoT) & Big Data. It is being used by industrial companies all over the world to increase flexibility while achieving cost savings, reduced inefficiencies, and better performance. It is no longer a trend for the future. But putting Industry 4.0 technology support into practice is a tough endeavour that gets increasingly harder in the absence of a common method. These are produced during the course of business operations and are kept in databases, email communication, transaction logs, free form texts on (business) social media, and other places. Businesses want to integrate data analytics methods into their decision-making processes by utilisation of these data. The field of Big Data analyses has seen tremendous progress in the IT sector in recent years. It appears that in order to deal with the extremely dynamic situations of today, new methods for product route mapping are required. This article provides an overview of the literature in science on product road mapping in order to shed light on the current state of the art & pinpoint research gaps. In order to demonstrate the influence of Industry 4.0 technological innovations on the manufacturing sector, this study provides an organised and content-focused evaluation of the literature. This paper offers recommendations for converting a legacy manufacturing facility into an Industry 4.0-compliant smart plant. Research gaps encompass topics including how to include objectives or results in product roadmaps, how to match a roadmap with the item's vision, and how to include activities related to product discovery in product roadmaps.

327. INCIDENCE OF GASTRIC BAND REMOVAL: A REVIEW OF THE LITERATURE

Abstract Purpose In the wake of the global obesity epidemic, bariatric surgery has become critical to prevent the complications of obesity and reduce the impact across health care systems. Laparoscopic Gastric Band insertion was at one point the most performed bariatric operation for obesity. In Australia, due to the limited publicly funded bariatric units, LAGB insertion is often performed in the private health sector. However, the post operative course for many of these patients who underwent LAGB has been fraught with complications often resulting in presentation to emergency, explantation of the LAGB and further surgical intervention. and is considered unfavourable in management of obesity. Methodology We performed a search of medical subject headings within PubMed, Medline and Embase for the terms ‘Gastric Band*’, ‘remov*’, ‘explant*. Following removal of duplicates, a total of 46 articles detailing the incidence of gastric band removals. Studies were included if they included discrete cohorts of patients who have undergone LAGB insertion, reported data on incidence of removal and median follow up >3 years. Results Results of the literature review will be discussed. Conclusion While it is considered unfavourable as a surgical option for management of obesity, public hospitals continue to absorb many patients who have undergone this procedure placing stress on an already stretched system. The incidence of LAGB varies in the literature. The authors would like to provide an updated review of the literature to determine the incidence of LAGB to better inform patients and health care providers.

Inquiry into Teaching Listening and Speaking in High School English Classes Based on an Activity Perspective

This paper conducts an in-depth analysis of the issues present in current high school English listening and speaking classes and proposes corresponding improvements. Firstly, it identifies the challenges faced by high school English listening and speaking instruction, including inadequate emphasis on training listening and speaking skills by teachers, lack of operational and measurable course objectives, monotonous forms of activity organization, limitations in the use of listening materials and tools, weak connections between introductory segments and thematic content, failure to understand listening and speaking discourse based on thematic significance, neglect of teaching learning strategies, absence of learning activities in authentic contexts, and singular evaluation methods. Subsequently, a series of suggestions for enhancing teaching quality and efficiency are put forward, such as designing instruction around thematic contexts that integrate listening, speaking, reading, viewing, and writing skills; fostering the development of students’ core competencies, particularly language ability and cultural awareness; conducting comprehensive, interconnected, and practical learning activities; utilizing modern information technology to create a culturally rich learning environment; and implementing formative and multifaceted evaluation mechanisms. These improvement measures aim to enhance students’ listening and speaking abilities and cultivate them as lifelong learners with good listening and speaking habits.

A nomogram predicting intraoperative adverse events during minimally invasive radical nephrectomy and thrombectomy.

To define the incidence and independent predictive factors of intraoperative adverse events (IOAEs) after minimally invasive radical nephrectomy and thrombectomy (RNAT) and to determine the impact of intraoperative adverse events on oncological outcomes. A total of 294 patients underwent minimally invasive RNAT from January 2010 to December 2023 in our center were included. IOAEs are defined as any deviation from the normal surgical procedure during the operation course. Multivariate logistic regression analysis was performed to identify the independent predictive factors of IOAEs. The Kaplan-Meier curves was used to compare overall survival and cancer-specific survival between patients with IOAEs or not. Seventy-four IOAEs occurred in 57 of 294 patients (19.4%) and the most frequent IOAEs were conversion to open surgery (42/74, 56.7%), followed by excessive hemorrhage (20/74, 27.0%). In multivariate logistic analysis, side (OR 0.0929; 95%Cl 0.0367-0.2160; p < 0.001), operation approach (OR 0.1762; 95%Cl 0.06828-0.4109; p < 0.001), and Mayo grade (OR 6.321; 95%Cl 3.846-11.13; p < 0.001) were independent predictive predictors of IOAEs during minimally invasive RNAT. IOAEs (OR 2.713; 95%Cl 1.242-5.897; p = 0.012) was an independent risk factor of the occurrence of postoperative complications. Between the patients with IOAEs or not, neither overall survival (OS) nor cancer-specific survival (CSS) showed statistical differences. Patients with postoperative complications show shorter OS and CSS. We found that the independent predictive factors of minimally invasive RNATwere side, operation approach and Mayo grade, and it is a risk factor of the occurrence of postoperative complications. In addition, the occurrence of IOAEs had no effect on long-term oncological outcomes.

Outcome of isolated and combined direct feminization laryngochondroplasty: Our first 20 cases

This retrospective study describes the surgical outcomes of our first 20 transgender women to undergo feminization thyroid laryngochondroplasty (FLC) by a direct transvestibular FLC (DTV-FLC) approach from December 2019 to October 2023. The medical records of all patients were retrieved and reviewed. Data on the operative, postoperative, and follow-up courses, complications, and functional and cosmetic outcomes were retrieved. The cosmetic results were evaluated by four independent facial plastic surgeons. Thirteen patients underwent DTV-FLC combined with genioplasty or genioplasty with mandibular angle reduction and seven underwent isolated DTV-FLC. DTV-FLC was feasible in all planned cases. Complications (skin flap perforation, thyroid cartilage fracture, mental hypoesthesia, hematoma, dehiscence of the vestibular incision, vestibular scar adhesions, and anemia) were minor and resolved spontaneously. The preoperative grade of thyroid cartilage protrusion was 1.9 ± 0.9 on a scale from 1 to 3. The postoperative cosmetic results of 18 patients were judged as having improved (a score of 2.1 ± 0.8 on a scale from −1 to 3). Eighteen patients were satisfied with the cosmetic result, one was dissatisfied (the revision surgery patient), and one was lost to follow-up. In conclusion, DTV-FTLC is a valid surgical approach for FLC, yielding high patient satisfaction and good cosmetic results.

Robotic-assisted ectopic mediastinal parathyroidectomy: a single institution experience and operative review for the thoracic surgeon.

Parathyroidectomy remains the only definitive cure for primary hyperparathyroidism (PHPT). In rare cases, ectopic hyperfunctioning glands are located in the mediastinum, necessitating a thoracic surgical approach. The objective of this project was to review a single high-volume institutional experience of this presentation, with specific attention to the use of a robotic-assisted thoracic surgery (RATS) approach. This was a single-center, 5-year retrospective cohort study. All patients who underwent RATS mediastinal mass resection (MMR) for PHPT at the University of Colorado Anschutz Medical Campus were targeted for inclusion. Patient cases were reviewed for demographics, history, operative data, laboratory values, and postoperative course. Eight patients underwent RATS-MMR for PHPT between 2018-2023. Median [interquartile range] operative time was 178 [138-213] minutes, and length of stay was 2.0 [1.5-2.0] days. One patient experienced post-operative chylothorax requiring dietary modification. There were no other 30-day complications or readmissions. Final pathology confirmed intrathymic parathyroid tissue in all patients. All patients achieved cure of PHPT. The robotic-assisted approach has low morbidity and associated hospital length of stay and can be safely used to cure PHPT. As this is a rare pathology with an infrequently utilized surgical approach, it is important to critically discuss the diagnostic evaluation and operative course, aimed at educating the thoracic surgeon who may encounter and assist in the management of these patients.

Enhancing Learning and Collaboration in a Unit Operations Course: Using AI as a Catalyst to Create Engaging Problem-Based Learning Scenarios

Enhancing Learning and Collaboration in a Unit Operations Course: Using AI as a Catalyst to Create Engaging Problem-Based Learning Scenarios

Научно-методический подход к разработке проектов опытно-промышленных испытаний открытой разработки месторождений

Methodology of designing pilot tests in open-pit mining is a complex and insufficiently developed issue in the theory and practice of designing mining systems, which, as a rule, fails to take into account the mining and geological features of the deposits. The complex development of mineral deposits requires new methods of open-pit designing. Thus, the theoretical justification and development of the methods to determine the optimal parameters and indicators of open-pits during the design of pilot tests with the establishment of scales, deadlines, tasks and test conditions is an urgent research problem. The authors of the study have systematized the research trends in developing the basis for designing pilot tests in open-pit geotechnology. The level of geological inaccuracies in case of insufficiently reliable prospecting results leads to a decrease in the expected technical and economic indicators of the mining project ranging from 5-20% to several folds. When information on the deposit is insufficient, pilot test projects are prepared. This is done in order to obtain additional input data for preparation of the feasibility study of permanent conditions or at the stage of the field development to verify the created technologies and means of their mechanisation in order to avoid revision of the mining system parameters in the course of the field operations due to discrepancies between the geomechanical and hydrogeological representations given in the detailed exploration materials and the real conditions.

Effectiveness of Nutritional Supplementation in Liver Transplant Recipients during Early Postoperative Course: A Systematic Review and Meta-Analysis

Abstract Background Nutrition is an integral part of health maintenance. The liver is the largest and most important metabolic organ, playing a pivotal role in integrating several biochemical pathways of carbohydrate, fat, protein, and vitamin metabolism. Malnutrition is a common complication of end- stage liver disease (ESLD). Progressive deterioration of nutritional status has been associated with poor outcome in cirrhotic patients. Liver transplantation (LT) revolutionized the management of liver disease. Nutritional therapy is an integral part of liver transplant care. Objective To identity the efficacy of different dietary nutritional supplements as zinc, vit D and immunonutrients (glutamine, omega 3, arginine and ribonucleic acid) for recipient at early post operative course. Material and Methods In this systematic review and meta-analysis we enrolled a total of 7 studies for assessing the clinical outcomes of ICU patients underwent liver transplantation surgery and supplied with dietary supplements during early postoperative period. The studies also assessed the laboratory assessment of patients postoperatively during ICU admission period. Results Regarding postoperative dietary supplementations with HMB, we found significant difference for appendicular skeletal muscle mass (ASMI) regarding the baseline and the postoperative ASMI in the intervention group with HMB. But we did not report significant difference regarding the baseline and the postoperative Fat-free mass index (FFMI) in both intervention and control group with HMB. Also we did not find significant difference between base line and postoperative in both groups for Mid-arm muscle-circumference (MAMC), Fat mass index (FMI), 6-minute walk test (6MWT), and Handgrip (HG). Data Sources Medline databases (PubMed, Medscape, ScienceDirect. EMF-Portal) and all materials available in the Internet till 2021. Conclusion BCAA as dietary supplementation showing a significant favorable effect regarding the baseline and the postoperative BTR levels, also for BCAA levels, Tyrosine levels, prealbumin levels, retinol binding protein and PTINR levels in both intervention and control groups. For HMB, we found significant difference for appendicular skeletal muscle mass (ASMI) regarding the baseline and the postoperative ASMI in the intervention group with HMB. But we did not report significant difference regarding the baseline and the postoperative Fat-free mass index (FFMI) in both intervention and control group with HMB.

The General Mathematics Course ‘Mathematics and Life Sciences’ for Non-science and Engineering Students

In modern society, alongside the rapid advancement of science and technology, the role and importance of mathematics are increasingly being emphasized. Such advancements, including data analysis and artificial intelligence development, rely fundamentally on mathematical thinking and theory, which have become essential elements across all academic disciplines. Against this backdrop, the role of university general mathematics education has become undeniably important. It is necessary not only for students in science and engineering, but also for those in the humanities and social sciences, to have access to balanced mathematical education. To this end, universities must focus on developing a variety of general mathematics courses. This paper presents a detailed case study of the design and operation of a basic general mathematics course titled “Mathematics and Life Sciences,” offered to students in the humanities and social sciences at Y University in Seoul. The course is structured to enable students to learn essential basic mathematics theories that are crucial across various disciplines and to apply them to phenomena in life sciences. In doing so, students will gain a better understanding of certain interdisciplinary connections as well as enhance their thinking and problem-solving skills. Additionally, this paper analyzes the educational effects and positive feedback from students obtained through a decade of continuous improvement in the content and operation of this course. Based on this analysis, this paper proposes future directions for development and research tasks in the educational field. This research is expected to contribute to the exploration of the direction in which university general mathematics education should head.

AN EVALUATION METHOD OF AN ENERGY CONSUMPTION AS AN OPERATION PARAMETER IN A CYBER-PHYSICAL SYSTEM

The research of energy consumption in an Internet of Things network and its analytical evaluation is the goal of this work. The authors of this work concentrate on developing a model for calculating the actual gain in power consumption in order to estimate the actual energy required. The method suggests measuring the difference in energy usage under three primary battery-powered working modes to maximize a device's lifetime. Due to the fact that each CPS device state has its own energy metrics, it is feasible to choose the best operation course for entire network. The presented technique is certainly viable, as demonstrated by the experimental examination of Zigbee and BLE devices. The comparison of power levels using a temperature sensor in three basic scenarios (power modes) dictates how the CPS device lifetime can be optimized. Multi-regime consumption models, in which the rates of charging and discharging are dependent upon the energy level, are analyzed in this paper. This work aimed to state an optimal energy consumption by finding the right balance between operational power and battery lifetime through mathematical modeling. Therefore, it is easy to determine the energy cost of power stage, for instance, to send data by setting the minimal duration of each working condition in terms of power consumption. Moreover, a reasonable balance of power consumption and battery lifetime which impacts the data collection from sensors is vital to the development of data extraction algorithms. The practical results depict how device should be accessible to be able to lose less power even during switching on/off or how operate more effective if it used for a short period of time. A long-term network could become a reality once battery life is optimized enough to not disturb a user.

Exploration on Task-driven Teaching Design of Industrial Robot Operation and Programming Course in Secondary Vocational Schools

Currently, the national goal for the training of talents in vocational colleges and universities is to cultivate high-quality skilled talents with powerful practical ability, good thinking, and in line with the needs of the manufacturing industry. For the industrial robot operation and programming, which is a comprehensive practical training course with both theory and practice, focusing on the improvement of students' Introductory operation, offline programming ability, and familiarity with the use of network communication systems and other learning objectives, it is proposed to apply the "task-driven teaching method" throughout the whole teaching process to fully mobilize students' initiative and guide them to analyze the problems and improve their practical skills from different perspectives. The article focuses on the requirements of the course and discusses how to improve the student's capacity to apply theory in practice. The article focuses on the specific teaching design ideas of the task-driven teaching method and the multi-dimensional evaluation and assessment mode in this course in combination with the requirements of the course.

Simulation medicine in obstetrics and gynaecology, possibilities for its use and the current state at the obstetrics and gynaecology departments in the Czech Republic.

Simulation medicine is no longer just a modern trend and has become a standard part of education and training of the medical staff and students in many countries around the world. Its validity and benefits have been acknowledged and its necessity is reflected in the recommendations of the European Board and College of Obstetrics and Gynaecology. The aim of our work was to map the current state of simulation training at large obstetrics and gynaecology departments in the Czech Republic including the equipment available, teaching environment conditions and human resources and to find out to what extent individual teaching methods are being used in undergraduate and postgraduate education. We have collected the information using a questionnaire which focused on the equipment available to the departments, teaching environment conditions, human resources, and types of simulation methods being used in undergraduate and postgraduate training as well as the spectrum of courses being offered. Our finding is that large obstetrics and gynaecology departments in the Czech Republic are well equipped, have good teaching environments available to them, and are able to use most of the current simulation teaching methods. On the other hand, except for an operative vaginal birth course, only a small number of other simulation courses are currently being offered. Data from the survey are further used to discuss the possibilities of developing simulation training in this field in the Czech Republic.

Interactive Optimization for Cartographic Aggregation of Building Features

AbstractAggregation, as an operation of cartographic generalization, provides an effective means of abstracting the configuration of building features by combining them according to the scale reduction of the 2D map. Automating this design process effectively helps professional cartographers design both paper and digital maps, but finding the best aggregation result from the numerous combinations of building features has been a challenge. This paper presents a novel approach to assist cartographers in interactively designing the aggregation of building features in scale‐aware map visualization. Our contribution is to provide an appropriate set of candidates for the cartographer to choose from among a limited number of possible combinations of building features. This is achieved by collecting locally optimal solutions that emerge in the course of aggregation operations, formulated as a label cost optimization problem. Users can also explore better aggregation results by interactively adjusting the design parameters to update the set of possible combinations, along with an operator to force the combination of manually selected building features. Each cluster of aggregated building features is tightly enclosed by a concave hull, which is later adaptively simplified to abstract its boundary shapes. Experimental design examples and evaluations by expert cartographers demonstrate the feasibility of the proposed approach to interactive aggregation.

Critical care therapies pre- and post-heart transplant and their impact: Analysis from the Pediatric Cardiac Critical Care Consortium

BackgroundFew studies highlighting the critical care management of patients after heart HTx (HTx) have been published to date. This analysis provides a contemporary representation of critical care burden pre- and post-HTx, describes care differences based on pre-transplant diagnosis and outlines the impact of intensive care unit (ICU) therapies on outcomes. MethodsData from PC4 Collaborative Registry was analyzed for pediatric patients undergoing HTx between 08/2014-04/2022. Results1877 HTx in 1857 patients were reported from 42 centers; 56.5% had congenital heart disease (CHD). Patients with CHD were younger, smaller, more likely male, White race, and publicly insured. Their pre-HTx ICU course was characterized by a higher need for catheterization, increased likelihood of inotropic support and mechanical ventilation with lower VAD rates. Their operative courses were significant for longer bypass and cross-clamp times. Postoperatively, CHD patients required more CPR and utilized more ICU therapies such as inotropes, ECMO and renal replacement. Those with CHD had a longer duration of ventilatory support (68.6 vs. 27.3 hours), total hospital stays (37.1 vs. 22.9 days) and higher hospital mortality (7.8% vs. 1.8%); all p<0.0001. Longer cardiopulmonary bypass and longer deep hypothermic circulatory arrest times and delayed sternal closure were independent risk factors for hospital mortality. Lastly, there was no association between total surgical volume for a center and outcomes but there was a significant relationship between center transplant volume and outcomes with higher volume centers demonstrating significantly lower mortality. ConclusionA diagnosis of CHD prior to HTx is associated with a greater use of ICU specific therapies compared non-CHD cohort. Operative factors, particularly in CHD patients, are independently associated with higher hospital mortality as was low transplant volume at the center. The study provides basis for further investigating ICU and operative factors that can be modified to improve transplant outcomes.

Anti-Hu antibody associated paraneoplastic neurological syndrome in a child with ganglioneuroblastoma: A rare case report and literature review.

Paraneoplastic neurological syndrome with anti-Hu antibody (Hu-PNS) is a neurological disorder that occur in patients with malignancy. The syndrome has a wide range of presentations and can present before diagnosis of primary malignancy. Familiarity with these paraneoplastic neurological syndromes can help early recognition and take appropriate regimens. Diagnosis and treatment of Hu-PNS. This is retrospective study that analyzed the clinical data of this case. Through retrospective analysis and targeted antibody screening, serum anti-Hu antibody was detected. Subsequent spinal imaging revealed a mass in the paraspinal region, which was confirmed as ganglioneuroblastoma by pathologic examination. The child was treated with a course of intravenous immunoglobulin and radical surgical operation without chemotherapy. The neurological symptoms were gradually improved and no signs indicate disease progression or tumor recurrence. Hu-PNS has rarely been reported in children with ganglioneuroblastomas. They can mimic non-neoplastic processes, making detection and diagnosis difficult. Serum and/or cerebrospinal fluid onconeural antibody can strongly indicate occult cancers. Early detection of paraneoplastic neurological syndromes can help take appropriate regimens and improve prognosis.