You have accessJournal of UrologyTrauma/Reconstruction/Diversion: External Genitalia Reconstruction and Urotrauma1 Apr 2016MP59-13 BURNS TO THE PERINEAL REGION INCREASE THE RISK OF DEATH AMONG U.S. SERVICE MEMBERS SUSTAINING COMBAT-RELATED BURNS DURING OPERATION IRAQI FREEDOM AND OPERATION ENDURING FREEDOM Michael Clemens, Judson Janak, Julie Rizzo, Michelle Buehner, Steven Hudak, John Graybill, and Kevin Chung Michael ClemensMichael Clemens More articles by this author , Judson JanakJudson Janak More articles by this author , Julie RizzoJulie Rizzo More articles by this author , Michelle BuehnerMichelle Buehner More articles by this author , Steven HudakSteven Hudak More articles by this author , John GraybillJohn Graybill More articles by this author , and Kevin ChungKevin Chung More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2016.02.832AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Burns to the perineal region (genitals, perineum, and buttocks) present a number of unique challenges and thus have been suggested to increase morbidity and mortality compared to burn patients without perineal regional involvement. Despite the large number of U.S. Service Members (SMs) who have sustained burns involving the perineal region during Operation Iraqi Freedom (OIF) and Operation Enduring Freedom (OEF), no studies have investigated the potential impact of such burns on mortality. The objective of this study was to evaluate the relationship between combat-related burns to the perineal region and mortality among U.S. SMs during OIF/OEF. METHODS The prospectively maintained burn registry from the only burn center in the Department of Defense (United States Army Institute of Surgical Research) was retrospectively reviewed to identify all SMs with combat-related burns sustained during OIF/OEF from March 2003-October 2013. The two primary risk factors of interest were any perineal regional burn (genital, perineal, OR, buttock burns) and complete perineal regional burn (genital, perineal, AND, buttock burns). To estimate the risk of mortality associated with perineal regional burns, we performed individual Cox proportional hazard models adjusting for severe non-burn-related comorbidities (non-burn ISS ≥ 16), percent total body surface area (%TBSA) burned, and inhalational injury. RESULTS Among the 902 SMs with combat-related burns sustained during the study period, 226 (25.0%) had perineal regional involvement. SMs with perineal regional burns had greater overall injury severity as demonstrated by more severe comorbid injuries (non-burn ISS ≥ 16 in 19.5% vs. 8.9%; p < 0.0001), larger burns (median TBSA=35% vs. 5%, p < 0.0001); and greater frequency of inhalational injury (32.7% vs. 10.8%, p < 0.0001) when compared to SMs with burns not involving the perineal region. Burns involving the genitals, perineum, and buttocks were associated with a 5-fold increased risk of mortality (HR: 5.3; 2.9-9.7). However, this risk did not persist in the final adjusted model (HR=1.8; 0.8-4.0). However, percent TBSA was identified as a potential negative effect modifier. Thus, when adjusting for percent TBSA, complete perineal regional burns were associated with an independent risk of death (HR=5.6; 2.45-12.7) among SMs with burn size of < 60% TBSA. CONCLUSIONS Combat-related burns involving the genitals, perineum, and buttocks increase the risk of mortality among SMs with burn size < 60% TBSA. © 2016FiguresReferencesRelatedDetails Volume 195Issue 4SApril 2016Page: e789-e790 Advertisement Copyright & Permissions© 2016MetricsAuthor Information Michael Clemens More articles by this author Judson Janak More articles by this author Julie Rizzo More articles by this author Michelle Buehner More articles by this author Steven Hudak More articles by this author John Graybill More articles by this author Kevin Chung More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...