Timely and accurate performance assessment and non-optimal regulation of industrial processes can effectively guarantee product quality. Most industrial processes are highly nonlinear and dynamic, so long short-term memory (LSTM) network is suitable for industrial performance assessment. However, in the network learning, the typical LSTM network focuses on the representation learning of input variables, lacks the representation of comprehensive economic indexes (CEI), and cannot selectively learn essential features, which increases the computational burden and easily mixes redundant information. Thus, a supervised slow feature analysis (SFA)-based LSTM (SSFALSTM) network is proposed for industrial operating performance assessment. By utilizing CEI information and SFA constraints, the network is guided to simultaneously learn features related to CEI and slow-changing features that reflect the inherent dynamics of the process. Further, cascade performance recognition model to construct the complete performance assessment framework. For the non-optimal performance, a reconstruction-based contribution plot method is proposed to identify the main cause variables and guide adjustment operations. Finally, the effectiveness of the proposed method is validated on the dense medium coal preparation process.