Abstract Plant protection products (PPP) are regulated products that require authorization in the country where they are sold. Operator and reentry worker safety when handling pesticides is one of the safety considerations that must be addressed as part of the registration process. Personal protective equipment (PPE) is one of the options for reducing operator and reentry worker exposure. Quality, comfort, cost, and availability are common constraints in the use of PPE that need to be addressed for it to be used effectively to mitigate risk. This requires stakeholders from the PPP and PPE sectors working together; it cannot be accomplished by any one group or entity alone. This process, which begins with compliance with regulations and ends with the possibility of the farmer/operator/reentry worker to protect themselves, requires a concerted effort. This article shows how international standards and expertise, as well as coordination of PPP and PPE stakeholders in France, resulted in the development and implementation of risk-based PPE requirements, which are acceptable to farmer/operator/reentry worker. The French example could be used by other countries that are governed by EU regulations. Additionally, the development of consistent labels and partnerships to promote clear consistent message has broader implications.