Transportation of minerals during open-pit mining works is mainly provided by heavy vehicles. One of the most dangerous accidents during the operation of vehicles in open-pit mines is the destruction of large-scale tires. The main cause of the destruction of tires is heating of rubber causing the increase of pressure of injected gas and change of properties of tire material. Apart from friction processes and rubber deformation causing heating of wheels, the temperature of tires can increase when affected by external heat sources. At coal mines, sources of auto-ignition of fossil fuels often located along the road shoulders and sometimes on the road surface can be additional sources of heat for the vehicles. According to the calculations, the increase in tire pressure does not depend on the type of gas injected. The temperature rise in tires, however, is significantly affected by the specific heat capacity and the density of the gas used. According to the conducted studies, carbon dioxide is a more effective gas compared with air or nitrogen. With a certain amount of heat emitted in the tire, air or nitrogen heats up from 0 to 100 °С, while the temperature of carbon dioxide will increase only to 72 °С. Due to heating, the air and nitrogen pressure in the tires will increase from 6 to 8.2 atm, whereas carbon dioxide pressure will increase only to 7.5 atm. Unlike air, carbon dioxide is not involved in the combustion and oxidation of heated rubber. Methane and its homologs are even more effective. For example, propane injected into tires, when emitting the same amount of heat, will heat up from 0 only to 28 °С, and its pressure will increase from 6 to 6.6 atm. The combustion of these hydrocarbons can be prevented by using inhibitors. Thus, adding 2–3 % of freons will make these gases non-flammable and explosion-proof.