Online Reports Research Articles

Social Media as Pharmacovigilance: The Potential for Patient Reports to Inform Clinical Research on Glucagon-Like Peptide 1 (GLP-1) Receptor Agonists for Substance Use Disorders.

The surge in popularity of semaglutide (Ozempic, Wegovy, Rybelsus) and other glucagon-like-peptide 1 (GLP-1) receptor agonists has been accompanied by widespread reports of unintended reductions in alcohol use (and other addictive behaviors) during treatment. With clinical trials of GLP-1 receptor agonists for substance use only recently under way, anecdotal reports (including via social media) are now a primary reason for interest in potential effects of GLP-1 receptor agonists on alcohol use in patient populations. The nature and volume of these reports raises the prospect that social media data can potentially be leveraged to inform the study of novel addiction treatments and the prioritization of behavioral or neurobiological targets for mechanistic research. This approach, which aligns with recent efforts to apply social media data to pharmacovigilance, may be particularly relevant for drug repurposing efforts. This possibility is illustrated by a thematic analysis of anonymous online reports concerning changes in alcohol use or alcohol-related effects during treatment with GLP-1 receptor agonists. These reports not only support the rationale for clinical trials but also point to potential neurobehavioral mechanisms (e.g., satiety, craving/preoccupation, aversion, altered subjective response) that might inform hypotheses for human laboratory and neuroscience studies. Refined methods for capturing patient reports of incidental medication effects on addictive behaviors at large scale could potentially lead to novel, pharmacovigilance-based approaches to identify candidate therapies for drug repurposing efforts.

Using the RE-AIM framework to assess national teledermatology expansion.

Teledermatology has been utilized in the United States Department of Veterans Affairs (VA) for decades but continues to have incomplete penetration. VA has funded an initiative to enhance access to dermatology services since 2017 to support asynchronous teledermatology for Veterans living in rural areas. As part of an ongoing evaluation of this program, we assessed the teledermatology activity between the fiscal years 2020 and 2022. We focused on the second cohort of the initiative, comprising six VA facilities and their 54 referral clinics. We studied teledermatology programs at cohort facilities using the reach, effectiveness, adoption, implementation, and maintenance framework. We used a mixed-methods design including annual online reports completed by participating facilities and VA administrative data. When possible, we compared the data from the 3 years of teledermatology funding with the baseline year prior to the start of funding. Reach: Compared with the baseline year, there was a 100% increase in encounters and a 62% increase in patients seen at the funded facilities. Over 500 clinicians and support staff members were trained. Effectiveness: In FY 2022, primary or specialty care clinics affiliated with the funded facilities had more dermatology programs than primary or specialty care clinics across the VA (83% vs. 71% of sites). Adoption: By the end of the funding period, teledermatology constituted 16% of dermatology encounters at the funded facilities compared with 12% nationally. This reflected an increase from 9.2% at the funded facilities and 10.3% nationally prior to the funding period. Implementation: The continued funding for staff and equipment facilitated the expansion to rural areas. Maintenance: By the end of the funding period, all facilities indicated that they had fully implemented their program for patients of targeted primary care providers. The Program Sustainability Index scores generally increased during the funding period. Targeted funding to support asynchronous teledermatology implementation for rural Veterans increased its reach, adoption, and implementation, ultimately improving access. Providing program guidance with staffing and training resources can increase the impact of these programs. Ongoing efforts to maintain and increase communication between primary care and dermatology will be needed to sustain success.

Promoting Surgeon-Scientists in Otolaryngology–Head and Neck Surgery—From Bench to Bedside

Surgeon-scientists (defined as principal investigators [PIs] with a Doctor of Medicine [MD] degree or a combined MD and Doctor of Philosophy [PhD] degree) in otolaryngology-head and neck surgery (OHNS) are imperative for achieving clinical translation in the OHNS field. To (1) raise awareness about the current state of surgeon-scientists in OHNS, (2) contextualize the landscape of surgeon-scientists in OHNS by comparing it to those of neurosurgery and ophthalmology, and (3) identify strategies for attracting and retaining surgeon-scientists in OHNS. Research funding data from fiscal years 2015 to 2021 among surgeon-scientists in OHNS, neurosurgery, and ophthalmology were obtained from the National Institutes of Health (NIH) Research Portfolio Online Reporting Tools Expenditures and Results and the US Department of Defense (DOD) Congressionally Directed Medical Research Programs awards database. The Association of American Medical Colleges provided the total number of active physicians in each specialty per year and the number and percentage of residents with an MD-PhD degree in each specialty per year. Cohen d was used to express the standardized value of the magnitude of the mean difference between compared groups. From 2015 to 2021, on average, there were 9566 active physicians in OHNS, 5559.8 in neurosurgery, and 18908.8 in ophthalmology. In OHNS, a greater number of NIH K (research career development) grants were held by surgeon-scientists than by PIs with a PhD degree (21.4 vs 5.1; mean difference, 16.3; 95% CI, 14.3-18.3; Cohen d = 9.6), whereas most NIH R (research) and U (cooperative agreement) grants (144.1 vs 81.6; mean difference, 62.6; 95% CI, 46.3-78.9; Cohen d = 4.5) and DOD grants (9.9 vs 4.1; mean difference, 5.7; 95% CI, 1.0-10.4; Cohen d = 1.4) were held by PIs with a PhD degree. In a comparison of OHNS to neurosurgery and ophthalmology, after the number of R and U grants was scaled by the number of physicians in each field, neurosurgery had a much greater number of grants per surgeon than OHNS (0.02 vs 0.01; mean difference, 0.01; 95% CI, 0.01-0.02; Cohen d = 4.2). Additionally, neurosurgeons received a much larger R and U grant amount per physician than otolaryngologists ($10 630.20 vs $4511.80; mean difference, $6118.40; 95% CI, $2625.90-$9610.80; Cohen d = 2.0). For the R and U grant metrics, there were no meaningful differences between OHNS and ophthalmology. Results of this database study showed that from 2015 to 2021, the number of governmental grants held by surgeon-scientists in OHNS increased, but there is room for improvement given the metrics of neurosurgeons, a population smaller than otolaryngologists. Possible strategies include intramural research grants, surgeon-scientist training programs, and partnerships between specialty societies and NIH administering institutes and centers.

Indonesian Government's Communication Messages on Covid-19 in the Perspective of Intermedia Agenda-Setting

The development of media towards digitalization has an impact on every field, including the public communication messages conveyed by the government, especially during the Covid-19 pandemic. It caused various responses from the public. The use of agenda-setting theory is considered quite adaptive in facing the changing times, and even in the digital era like today. This happened to the Indonesian leader who wrote a tweet about the New Normal in several fields as solutions facing the Covid-19 pandemic. Community responses related to Responses to Local Governments, Economic Issues, and Health Protocols were measured by big data analysis by using the IMM system for online media analysis and the ISA system for Twitter analysis. The results show that the intermedia agenda-setting or the transfer of issues from online media to Twitter happened on government public communication messages on the topic of New Normal and vice versa. However, discussions on Twitter about Local Governments led to discussions on online media and reports on Twitter about Economic Issues caused coverage on online media only. Those results had no responses from online media to Twitter. In addition, on the issue of Health Protocol, each agenda on online media and Twitter differed from one another. Keywords: Government messages, intermedia agenda-setting, online media, public communication, Twitter.

Pathway to Independence Awards (K99/R00): Funding Dynamics and Prediction of Future National Institutes of Health Research Project Funding.

The authors used the National Institutes of Health (NIH) RePORTER (Research Portfolio Online Reporting Tools) to evaluate funding trends and historic NIH investment increase in the K99 award pathway and examine whether R00 to R01 or R21 achievement time correlated with the future success of an early-stage NIH-funded investigator. All K99 awards and funding data in this study were limited to all clinical departments. The authors identified all researchers and awards through a K99 search from fiscal years (FYs) 2007 to 2022 across all clinical departments and investigated trends in K99 awards and funding from NIH FYs 2007 to 2022. They generated an R00 data set and analyzed the K99 to R00 achievement statistics from FYs 2007 to 2022. The authors aggregated NIH annual data files for FYs 2007 to 2021 to generate a master data file of all R01 and R21 awards. They linked R01 and R21 award data to the researcher previously identified through the K99 search and focused on the connection between K99/R00 awardees and subsequent R01 or R21 awards. From FY 2008 to FY 2022, the NIH K99 budget increased 127.0%, whereas the NIH program-level budget increased 17.3%. A principal investigator's mean funding per year significantly decreased as time from R00 to R01 or R21 increased ( P < .001); 7 of 15 comparisons differed significantly (2 at P < .01 and 5 at P < .001). NIH investment in the K99 award pathway has substantially outpaced the NIH program-level budget increase, and there is a strong association between mean funding per year since the start of the R00 phase and time from R00 to R01 or R21. This analysis may be useful to clinical departments as they evaluate selecting new and retaining current biomedical scientists for independent research positions.

Academic productivity and NIH funding for anesthesiology departmental chairs: A 15-year comparison

Study objectiveThis study evaluated whether there were improvements in the number of departmental National Institutes of Health (NIH) training grants and the academic productivity of departmental chairs in terms of NIH research funding and PubMed-cited publications when compared to chairs of the same departments in 2006. DesignEach chair was identified from the Society of Academic Associations of Academic Anesthesiology & Perioperative Medicine's Association of Academic Anesthesiology Chairs and entered into the NIH Research Portfolio Online Reporting Tools (RePORTER), PubMed, SCOPUS, and the National Provider Identifier Registry. MeasurementsThe number and funding amounts of training grants awarded to the department in 2010, 2015, and 2020 were obtained as well as the department's national ranking and total dollar amount for NIH funding in 2020. For the current chair cohort, total publications and m-quotient (h-index corrected for active research years) were recorded along with each chair's history of NIH grant funding. These data were compared to a previous study of anesthesiology chairs that reviewed funding and publications through 2006. Main resultsWe analyzed data from 100 academic departments of anesthesiology and compared their scholarly activity relative to data gathered in 2006. In 2020, 52 of 100 departments of anesthesiology had evidence of NIH funding. There were not statistically significant (P > 0.05) differences in grants funding obtained by chairs between 2006 and 2020 with the exception that more chairs in 2006 had program or center grants. Median publications for chairs significantly increased from 35 in 2006 to 55 in 2021 (IRR = 1.5, 95% CI = 1.2–2.0, P = 0.003). Nineteen percent of chairs were female, which did not significantly differ from the proportion of women in the 2006 paper (15%, χ2 = 0.57, df = 1, P = 0.452). Of the male chairs, 90% were professors whereas 63% of female chairs were professors (χ2 = 8.8, df = 1, P = 0.003). Female chairs had fewer publications than male chairs (IRR = 1.8, 95% CI = 1.2–1.8, P = 0.002); however, m-quotients were not significantly different between men and women (P = 0.602). ConclusionsWhen compared to 2006, department of anesthesiology chairs had more publications in 2021; however, NIH funding rates remained unchanged. The specialty had 19% female chairs, and those chairs had fewer publications than their male counterparts, though sex differences were attenuated using metrics that account for disparities in career length.

Gender Differences in Academic Rank, Leadership, and Awards Among NIH Grant Recipients in Diagnostic Radiology.

Objective: Females have been traditionally underrepresented in academia across multiple medical specialties, including radiology. The present study investigated primary investigators (PIs) who received National Institutes of Health (NIH) radiology funding between 2016 and 2019 to establish if there was a correlation between NIH grants, gender, academic rank, first and second tier leadership positions, geographic location, and professional awards. Materials and Methods: Funding information was obtained from the NIH Research Portfolio Online Reporting Tools Expenditure and Results (RePORTER) website for 2016-2019. Information for each PI was obtained from academic institutional websites, LinkedIn, and Doximity. Mann-Whitney U tests and chi-square analyses were performed to compare and determine associations between gender and the stated variables of interest. Results: Of the 805 radiology PIs included in this study, 78% were male. There was a significant association of gender with the attainment of the highest academic rank (p = 0.026), with females occupied more of the assistant professor ranks (M:F = 1:1.5) and less of the professor ranks (F:M = 1:1.2). Between genders, there was no significant difference in first and second tier leadership positions (p = 0.497, p = 0.116), and postgraduate honors and awards (p = 0.149). The greatest proportion of grants was awarded in the setting of sole male PIs (55%) and the least proportion of grants were awarded when the contact PI and other project leader were female (1%). Conclusion: Despite having similar academic credentials, including number of leadership positions and postgraduate honors and awards, female radiology PIs who have received NIH grants continue to be underrepresented in higher academic ranks.

IMPLEMENTASI PROGRAM KERJASAMA THAILAND DI BIDANG PARIWISATA MELALUI INDONESIA-MALAYSIA-THAILAND GROWTH TRIANGLE (IMT-GT) TAHUN 2017-2021

The purpose of this study was to find out Thailand's implementation of IMT-GT subregional cooperation in increasing tourism in the 2017-2021 period. The cooperation between the three countries, known as the Growth Triangle, is a transnational economic zone intertwined with adjacent geographical areas. The research method uses a qualitative descriptive approach, with the scope of this research starting from 2017 to 2021, according to the time period of the IMT-GT Implementation Blueprint. This research is descriptive in nature and is of a qualitative type using literature study data collection techniques or collecting data appropriate to the research topic, such as online journals, online reports, such as the official Thai tourism website, the official IMT-GT website, ASEAN, global media news, Thailand, Malaysia, and Indonesia. The results of this study indicate that based on the regional strategic plan focusing on the tourism sector in the implementation of the IMT-GT blueprint, Thailand's policy implementation is divided into two focuses, namely building infrastructure consisting of building tourist attractions and building transportation facilities which aim to increase connectivity between IMT-GT sub-regions, as well as the Thai government's tourism promotion or marketing to increase international tourist arrivals, both globally, and from IMT-GT countries.

Spending on Phased Clinical Development of Approved Drugs by the US National Institutes of Health Compared With Industry

The launch of the Advanced Research Projects Agency for Health to advance new cures and address public concern regarding drug prices has raised questions about the roles of government and industry in drug development. To compare National Institutes of Health (NIH) spending on phased clinical development of approved drugs with that by industry. This cross-sectional study examined NIH funding for published research reporting the results of phased clinical trials of drugs approved between 2010 and 2019 and compared the findings with reported industry spending estimates. Data analysis was performed between May 2021 and August 2022 using PubMed data from January 1999 through October 2021 and NIH Research Portfolio Online Reporting Tools Expenditures and Results data from January 1999 through December 2020. Drugs approved between 2010 and 2019. National Institutes of Health funding for published research describing applied research on approved drugs, basic research on their biological targets, and phased clinical trials related to drugs approved between 2010 and 2019 were evaluated using Mann-Whitney U tests. All costs were inflation adjusted to 2018. National Institutes of Health funding for basic or applied research related to 386 of 387 drugs approved between 2010 and 2019 totaled $247.3 billion. Of this amount, $8.1 billion (3.3%) was related to phased clinical development. This funding contributed to 12 340 publications on phased clinical trial results involving 240 of 387 (62.0%) drugs. Average NIH spending was $33.8 million per drug, including $13.9 million per drug for phase 1, $22.2 million per drug for phase 2, and $12.9 million per drug for phase 3 trials. Spending by NIH on phased development represented 9.8% to 10.7% of estimated industry spending, including 24.6% to 25.3% of estimated phase 1, 21.4% to 23.2% of phase 2, and 3.7% to 4.3% of phase 3 costs. Considering 60 products for which estimated industry costs were publicly available, NIH spending on clinical trials was significantly lower than estimated industry spending (sum of averages, $54.9 million per drug; mean difference, $326.0 million; 95% CI, $235.6-$416.4 million; 2-tailed paired t test P < .001). More than 90% of NIH funding came through cooperative agreements or program projects and centers, while 3.3% of NIH funding came through investigator-initiated research projects. In this cross-sectional study, NIH funding for phased clinical development of drugs approved between 2010 and 2019 represented a small fraction of NIH spending on pharmaceutical innovation. This spending focused primarily on early-phase clinical trials and research capacity and was significantly less than estimated industry spending on clinical development. These results may inform the efficient allocation of government funding to advance pharmaceutical innovation.

Twenty Years After the EMS Research Agenda: Trends in Emergency Medical Services Publications and Research Funding.

Since its publication in 2001, the National EMS Research Agenda has brought attention to a relative paucity of emergency medical services (EMS)-specific research and has called for an increase in funding and infrastructure to support EMS research. We investigated the trends in EMS-specific publications and National Institutes of Health (NIH)-funded research grants in the 20 years since this landmark publication. We performed a structured PubMed search of English-language citations from 2001 to 2020 to identify publications with populations, settings, or topics related to EMS care, education, or operations. Publications in trade journals and studies not involving humans were excluded. We also queried NIH Research Portfolio Online Reporting Tools Expenditures and Results (RePORTER) using a similar structured search. Titles, keywords, and abstracts were reviewed. Descriptive statistics were calculated, and nonlinear trends were described using segmented regression models. A total of 183,307 references met the search criteria in PubMed, and 4,281 grants were identified in NIH RePORTER. After removing duplicates, 152,408 titles were screened, with 17,314 (11.5%) included. EMS-related publications increased from 419 in 2001 to 1,788 in 2020, a 327% increase, compared with a 197% increase in total PubMed publications. There was a statistically significant nonlinear (J-shaped) increase in EMS publications after 2007. There were 1,166 funded EMS-related NIH grants, with a 469% increase from 2001 to 2020 compared with an 18% increase in overall NIH awards. Although total publications have doubled in the United States over the past 20 years, EMS-specific research has more than tripled and the number of funded EMS research grants has increased nearly 5-fold. Future evaluation should examine the quality of this research and its application to clinical practice.

Limited number of spine surgeons among recipients of National Institutes of Health grants awarded for degenerative spine disease research.

Surgeon scientists remain underrepresented among recipients of National Institutes of Health (NIH) grants despite their unique ability to perform translational research. This study elucidates the portfolio of NIH grants awarded for degenerative spine diseases and the role of spine surgeons in this portfolio. The most common diagnoses and surgical procedures for degenerative spine diseases were queried on the NIH Research Portfolio Online Reporting Tools Expenditures and Results (RePORTER) database (2011-2021). Total NIH funding was extracted for 20 additional clinical areas and compound annual growth rates (CAGRs) were calculated. A retrospective cohort study of principal investigators (PIs) was conducted. NIH grants and funding totals were extracted and compared to those from other clinical areas. The total NIH research budget increased from $31 to $43 billion over the 10-year period (CAGR 3.4%). A total of 273 unique grants equaling $91 million (CAGR 0%) were awarded for degenerative spine diseases. Diabetes ($11.8 billion, CAGR 0%), obesity ($10.6 billion, CAGR 3%), and chronic pain ($5.6 billion, CAGR 7%) received the most funding. Most NIH funding for degenerative spine disease research was awarded through the R01 (66%) and R44 (8%) grant mechanisms. The National Institute of Arthritis and Musculoskeletal and Skin Diseases awarded the most NIH funding (64%). Departments of orthopedic surgery were awarded the most funding (32%). NIH funding supported clinical (28%), translational (37%), and basic science (35%) research. Disease mechanisms (58%), imaging modalities (20%), and emerging technologies (16%) received the most funding. Nineteen spine surgeons were identified as PIs (16%). There were no significant differences in NIH funding totals by PI demographic and academic characteristics (p > 0.05)-except for full professors, who had the most NIH funding (p = 0.007) and highest h-index values (p < 0.001). Few spine surgeons receive NIH grants for degenerative spine disease research. Future opportunities may exist for spine surgeons to collaborate in identified areas of clinical interest. Additional strategies are needed to increase NIH funding in spine surgery.

‘Integration is not a one-way process’: students negotiating meanings of integration and internationalization at home (IaH) in Finnish higher education

ABSTRACT Internationalization at home (IaH) policies in higher education institutions (HEIs) are rarely negotiated with and by students. Therefore, students’ takes on such policies could be missed opportunities for HEIs. This qualitative study investigates international and local students’ negotiations and meaning-making of integration and IaH as stated by institutional policies. The data consist of online forum entries and reports from small group discussions between 40 students in English medium master’s programs in Finland (Europe). The key concepts of ideology and imaginary serve as entries into data analysis, which consists of enunciative discourse analysis. The findings indicate a perceived hierarchy of mutual but not equal integration between university staff, local and international students. Furthermore, the categories of ‘international as guests’ and ‘local students as hosts’ are challenged by the participants. Local students are considered as ‘guests with more privilege’ and international students as ‘guests with less opportunities’. The responsibility to achieve IaH goals is perceived to be unequally distributed among these actors. Practical implications include reconsidering the categories of ‘international’ and ‘local’ students and how IaH policies could share the responsibilities to achieve their goals more equally among students and staff.

National Institutes of Health funding among vascular surgeons is rare

BackgroundThe National Institutes of Health (NIH) is an essential source of funding for vascular surgeons conducting research. NIH funding is frequently used to benchmark institutional and individual research productivity, help determine eligibility for academic promotion, and as a measure of scientific quality. We sought to appraise the current scope of NIH funding to vascular surgeons by appraising the characteristics of NIH-funded investigators and projects. In addition, we also sought to determine whether funded grants addressed recent Society for Vascular Surgery (SVS) research priorities. MethodsIn April 2022, we queried the NIH Research Portfolio Online Reporting Tools Expenditures and Results (RePORTER) database for active projects. We only included projects that had a vascular surgeon as a principal investigator. Grant characteristics were extracted from the NIH Research Portfolio Online Reporting Tools Expenditures and Results database. Principal investigator demographics and academic background information were identified by searching institution profiles. ResultsThere were 55 active NIH awards given to 41 vascular surgeons. Only 1% (41/4037) of all vascular surgeons in the United States receive NIH funding. Funded vascular surgeons are an average of 16.3 years out of training; 37% (n = 15) are women. The majority of awards (58%; n = 32) were R01 grants. Among the active NIH-funded projects, 75% (n = 41) are basic or translational research projects, and 25% (n = 14) are clinical or health services research projects. Abdominal aortic aneurysm and peripheral arterial disease are the most commonly funded disease areas and together accounted for 54% (n = 30) of projects. Three SVS research priorities are not addressed by any of the current NIH-funded projects. ConclusionsNIH funding of vascular surgeons is rare and predominantly consists of basic or translational science projects focused on abdominal aortic aneurysm and peripheral arterial disease research. Women are well-represented among funded vascular surgeons. Although the majority of SVS research priorities receive NIH funding, three SVS research priorities are yet to be addressed by NIH-funded projects. Future efforts should focus on increasing the number of vascular surgeons receiving NIH grants and ensuring all SVS research priorities receive NIH funding.

Design and ergonomics analysis of workstation for online learning during movement control order

This paper discusses workstation design based on ergonomics using Rapid Upper Limb Assessment (RULA). The workstation was designed and the RULA was performed using CATIA software. This study focuses on personal experience when using the chair and desk during online learning, studies, conducting assignments, and reports, therefore, the initial data was derived from this experience then the data was analyzed using RULA to achieve a better score with an acceptable level of Musculoskeletal-Disorder risks. Then, only the chair was optimized to obtain a final score of 1 (best posture) from a score of 3.

Israeli media coverage of international male and female politicians: Gender and ethnopolitical aspects

AbstractIn 2015, the Israeli newspaperYedioth Ahronothbegan a campaign against Sweden’s Foreign Minister, Margot Wallström, who is considered a prominent critic of Israeli policy in Palestine. The campaign included various aspects of media bias on both the gender and the ethnopolitical levels and thus raised the question of a possible relationship between these two types of biases. Studies in relation to political communication and gender have traditionally focused on the media coverage of domestic male and female politicians. The present study attempts to examine the gender media coverage of prominent international political actors. It performs a mixed content analysis of 529 news items from three Israeli online newspapers, reports, and articles, which cover world-renowned public figures (among them, Wallström). Each news item is coded into three gender-coverage frames. Additionally, a critical reading of the journalistic texts is conducted. The findings reveal that the combination of the two types of biases, the gender and the political, escalates the media sensation and stereotyping.

(548) NIH Funding Trends for Men's and Women's Urologic Conditions

Abstract Introduction Existing literature reports a general trend of increasing National Institutes of Health (NIH) funding for surgeon-scientists in America and shows that urology has not benefited from this trend. NIH funding for urologists continues to lag behind that of our peers in other surgical specialties. Between 2010-2019 urology departments received the second-lowest amount of NIH funding of all surgical specialties, only above plastic surgery. The literature also shows that NIH awards significantly less money to male cancer research (i.e., prostate cancer) than female cancer research (i.e., breast cancer). We sought to explore further gender-specific grant variation within NIH urologic funding by exploring dollars awarded to benign gender-specific non-cancer topics of urologic research. We hypothesized that an NIH funding disparity would exist between men’s health urologic research and research devoted to women’s health urologic issues. Objective To explore NIH funding trends for men's and women's urologic health conditions via the NIH Reporter database Methods We used the publicly available NIH Research Portfolio Online Reporting Tools Expenditures and Results (NIH RePORTER) to perform our data collection. NIH RePORTER is an online search tool of the repository of NIH-funded research projects and is linked to publications, patents and clinical trials resulting from NIH funding. Data was queried for a ten-year period between 2012-2021. We used uniform search parameters including “Department Type: urology” to filter for publications from departments of urology, “Funding Mechanism: research project grant” to eliminate R&amp;D, and “Award Type: new” to capture only first-time awards in our search period. All authors were included in our search, which encompassed both trainees and non-trainees independent of Activity Code. We selected four women’s urological health issues and four men’s urological health issues to guide a keyword search. Our women’s urological health issues included overactive bladder, incontinence, and pelvic organ prolapse. In addition, we queried the NIH Spending Category of “Women’s Health”. Our men’s urological health issues include erectile dysfunction, Peyronie's disease, hypogonadism and male stress incontinence. Search terms related to these health conditions were used to query project title, projects terms and project abstracts in the NIH RePORTER. Results Results of our research findings are summarized in Table 1. Of the 12 projects identified that exclusively investigate either a men’s health condition or a women’s health condition, 7 focused on men’s health and 5 on women’s health. NIH spending on women’s health issues exceeded that for men's health conditions by $833,964, a 51% difference, even though fewer projects were identified related to women’s health conditions. Overall, fewer gender-exclusive projects were found than expected. For example, incontinence projects frequently included both male and female-bodied participants. Conclusions NIH appears to devote substantially less funding for investigating benign urologic men’s health issues than benign urologic women’s health issues. Further examination of this funding gap is warranted, and if confirmed it would be prudent to improve NIH urologic funding in general and men’s health research funding specifically. Disclosure Any of the authors act as a consultant, employee or shareholder of an industry for: Coloplast.

Association for Academic Surgery/Society of University Surgeons research awards are highly successful in fostering future surgeon–scientists

BackgroundThe surgeon–scientist brings a unique perspective to surgical research. The Association of Academic Surgeons and Society of University Surgeons foster the development of surgeon–scientists through foundation awards to residents and junior faculty. We sought to evaluate the academic success of surgeons who received an Association for Academic Surgery/Society of University Surgeons award. MethodsInformation was collected for individuals who received a resident or junior faculty research award from the Association for Academic Surgery or Society of University Surgeons. Google Scholar, Scopus, and the National Institutes of Health Research Portfolio Online Reporting Tools: Expenditures and Results were used to assess scholarly achievements. ResultsEighty-two resident awardees were included, 31 (38%) of whom were female. Thirteen (24%) are now professors, 12 (22%) are division chiefs, and 4 (7%) are department chairs. Resident awardees have a median of 886 citations (interquartile range 237–2,111) and an H-index of 14 (interquartile range 7–23). Seven (13%) went on to receive K08/K23 awards, and 7 (13%) received R01s, with a total of about $200 million in National Institutes of Health funding (79-fold return on investment). Thirty-four junior faculty awardees were included, 10 (29%) of whom were female. Thirteen (38%) are now professors, 12 (35%) are division chiefs, and 7 (21%) are department chairs. Faculty awardees have a median of 2,617 citations (interquartile range 1,343–7,857) and an H-index of 25 (interquartile range 18–49). Four (12%) received K08 or K23 awards, and 10 (29%) received R01s, with about $139 million in National Institutes of Health funding (98-fold return on investment). ConclusionAssociation for Academic Surgery/Society of University Surgeons research awardees experience high degrees of success in academic surgery. Most resident awardees pursue fellowship training and remain in academic surgery. A high percentage of both faculty and resident awardees hold leadership positions and successfully achieve National Institutes of Health funding.

Rates of National Institutes of Health Funding for Surgeon-Scientists, 1995-2020

Surgeon-scientists are uniquely positioned to facilitate translation between the laboratory and clinical settings to drive innovation in patient care. However, surgeon-scientists face many challenges in pursuing research, such as increasing clinical demands that affect their competitiveness to apply for National Institutes of Health (NIH) funding compared with other scientists. To examine how NIH funding has been awarded to surgeon-scientists over time. This cross-sectional study used publicly available data from the NIH RePORTER (Research Portfolio Online Reporting Tools Expenditures and Results) database for research project grants awarded to departments of surgery between 1995 and 2020. Surgeon-scientists were defined as NIH-funded faculty holding an MD or MD-PhD degree with board certification in surgery; PhD scientists were NIH-funded faculty holding a PhD degree. Statistical analysis was performed from April 1 to August 31, 2022. National Institutes of Health funding to surgeon-scientists compared with PhD scientists, as well as NIH funding to surgeon-scientists across surgical subspecialties. Between 1995 and 2020, the number of NIH-funded investigators in surgical departments increased 1.9-fold from 968 to 1874 investigators, corresponding to a 4.0-fold increase in total funding (1995, $214 million; 2020, $861 million). Although the total amount of NIH funding to both surgeon-scientists and PhD scientists increased, the funding gap between surgeon-scientists and PhD scientists increased 2.8-fold from a $73 million difference in 1995 to a $208 million difference in 2020, favoring PhD scientists. National Institutes of Health funding to female surgeon-scientists increased significantly at a rate of 0.53% (95% CI, 0.48%-0.57%) per year from 4.8% of grants awarded to female surgeon-scientists in 1995 to 18.8% in 2020 (P < .001). However, substantial disparity remained, with female surgeon-scientists receiving less than 20% of NIH grants and funding dollars in 2020. In addition, although there was increased NIH funding to neurosurgeons and otolaryngologists, funding to urologists decreased significantly from 14.9% of all grants in 1995 to 7.5% in 2020 (annual percent change, -0.39% [95% CI, -0.47% to -0.30%]; P < .001). Despite surgical diseases making up 30% of the global disease burden, representation of surgeon-scientists among NIH investigators remains less than 2%. This study suggests that research performed by surgeon-scientists continues to be underrepresented in the NIH funding portfolio, highlighting a fundamental need to support and fund more surgeon-scientists.

Care-based community communication, capacity, and agency during the COVID-19 pandemic: Evidence from the Complexo da Maré Favela, Brazil

Scholars and officials have argued that the strengthening of communities and community-led development constitute an important policy goal in the fight against emergencies such as the COVID-19 pandemic. Nevertheless, most strategies to address such crises fail to consider the significance of community-driven solutions, community-level knowledge, and actors. At the same time, researchers have recognized that communication, such as through local newspapers, promotes community development by increasing communities’ social capital and cohesion. But the role of community communication in the encouragement and exercise of other levels of agency and in the development of community capacity, including to address emergencies, remains underexplored. This article investigates whether and how community journalists in a Rio de Janeiro favela have expressed and sought to develop favela residents’ individual and collective agency during the COVID-19 pandemic. We do so by analyzing thematically the COVID-19 virus-related articles that appeared in a community-based newspaper, Maré Online, between March and September 2020. We also conducted semi-structured interviews with Maré Online reporters to augment our analysis and supplemented that data with participant observation of relevant virtual community-led organizing meetings and events. Our study shows how community-based journalists revealed and promoted individual and collective agency through what we term a “care-based, participatory solutions journalism,” which supported favela residents’ “communicative freedom” as conceptualized by Benhabib (2013). This analysis stresses the connection between communicative freedom and community capacity. It illustrates the importance of community-produced communication in development of and in community, especially when those populations are pejoratively framed in the media, public policy, and often also, research.

Workshop Pembuatan Rapor Secara Otomatis dengan Google Workspace di SMK IDN Boarding School Jonggol

Advances in technology make it easy for everyone with regards to the ease of obtaining and managing information. One clear example is the development of the internet which has become an icon of technological development. Especially in the era of education 4.0, the internet plays an important role in the educational process. In the era of education 4.0 educators and students are required to be able to integrate technology in every educational activity. One of the applications of technology in education today is the existence of an internet-based report card information system or what we usually know as online report cards. This service is a literature study that aims to collect information related to the use of the online report card information system implemented by several schools. The results obtained from this literature study are that the online report card system makes it easy for educators or teachers at SMK IDN Boarding School Jonggol to process student value data which can be accessed by both students and parents