Structure/Method/Design: The development of the textbook began with the editor recruiting an editorial board of diverse experts, who then assisted in determining textbook content and identifying pertinent clinicians as chapter authors. Leadership from the Consortium of Universities for Global Health and the former GHEC provided critical input on selecting editorial board members, chapter contributors, and textbook content. Chapter content was developed through an intense and iterative process between chapter authors and the editorial board, including several stages of drafting, reviewing, editing, and revising. We also partnered closely with illustrators from Wiley-Blackwell to produce a text rich in illustrations and photographs. Outcomes & Evaluation: Essential Clinical Global Health includes contributions from nearly 100 global health experts, with content organized into 37 chapters and 6 sections: Introduction; Newborn and Child Health; Adolescent, Reproductive, and Maternal Health; Infectious Diseases; Non-Communicable Diseases; and Other Global Health Topics. Chapters cover the clinical diagnosis, management, and prevention of the leading causes of morbidity and mortality in lowand middle-income countries, along with special chapters on resource-limited health systems and other contextual topics, for example, “Working clinically in resourcelimited settings,” “Preparing for travel and staying safe abroad,” “Neglected tropical diseases,” “Laboratory skills,” “Nursing care,” “Pharmacy,” “Global health technologies,” “Illness in returning travelers,” and “Developing a career in global health.” Each chapter features key learning objectives, evidence-based clinical guidelines, practical clinical skills, realworld experiences from trainees and clinicians in the field, and core readings. The textbook’s accompanying electronic supplement contains additional resources, videos, and self-assessment questions and answers as well as an electronic version of the complete textbook e valuable for reference abroad on a laptop, tablet, or mobile device. Going Forward: As this collaborative textbook is published the beginning of 2015, our goal is to make it widely accessible to individual global health students, trainees, and clinicians, as well as to all institutions with global health programs. We welcome feedback from the global health community on how to improve future editions of Essential Clinical Global Health. We are also working with WileyBlackwell to develop online CME offerings based upon the textbook. Funding: None Abstract #: 01ETC068