One-way ANOVA Test Research Articles

Attitudes and intentions of parents towards the COVID-19 vaccine for their children at a special moment of the pandemic.

This research was conducted following the FDA's approval of the COVID-19 vaccine for children aged 5 to 11. Our study aimed to evaluate parents' intentions regarding vaccinating their children in response to the pandemic situation. This period was crucial for understanding parents' initial reactions to health authority recommendations. This descriptive cross-sectional study was conducted with 940 parents. The data were obtained using the Personal Information Form, the COVID-19 Anxiety Scale, and the Scale of Attitudes Towards COVID-19 Vaccine. Descriptive data analysis involved calculating frequency, percentage, mean, and standard deviation values. We employed Student's t-test, one-way ANOVA tests for analysis. Additionally, various characteristics were analyzed using the two-way logistic regression method. In the study, 85.1% of the parents reported having received the COVID-19 vaccine themselves. However, only 20% stated they would accept the COVID-19 vaccine for their children. The intention to vaccinate their children was influenced by factors such as the parent's age, level of COVID-19 anxiety, vaccination status, and knowledge about the COVID-19 vaccine. Despite the FDA's declaration, it was determined that more than two-thirds of parents were hesitant about the COVID-19 vaccine for their children.

Clinical and Biochemical Differences in Patients Having Non-Variceal Upper Gastrointestinal Bleeding on NSAIDs, Oral Anticoagulants, and Antiplatelet Therapy.

Introduction: Upper gastrointestinal bleeding (UGIB) is among the most common causes of morbidity and mortality worldwide, accounting for major resource allocation and increasing incidence. This study aimed to evaluate the severity of non-variceal bleeding in patients at risk of bleeding through the use of NSAIDs, oral anticoagulants, and antiplatelet therapy. Material and Method: The study included 296 patients admitted in the Gastroenterology Department of the Municipal County Emergency University Hospital, Timisoara, between 01.01.2018 and 01.04.2020, and diagnosed via gastroscopy with non-variceal gastrointestinal bleeding. The patients were divided among four groups based on their use of different drugs known to induce UGIB, i.e., aspirin and clopidogrel, NOACs, NSAIDs, and anti-vitamin K drugs, respectively. Statistical analyses were performed based on ANOVA one-way tests for continuous variables and Chi-square tests for categorical variables with pairwise comparisons based on Bonferroni adjusted significance tests. Results: The results showed several parameters having statistical significance among the different groups of patients. Patients on NOACs had statistically significant lower hemoglobin levels, lower hematocrit values, lower erythrocytes, lower RDW and higher fibrinogen levels compared to patients on VKA. Discussion: Surprisingly, the results from our study suggest that the use of NOACs was associated with a higher risk of bleeding when compared to VKA, which differs from the existing literature. Conclusions: One of the important factors causing upper non-variceal bleeding can be iatrogenic, either due to antiplatelet drugs or anticoagulants, to which NSAID treatment is additionally associated for various reasons. In our study, the use of NOACs seemed to have a more severe bleeding spectrum with higher morbidity compared to VKA.

Thermal Facial Profile and Orofacial Myofunctional Aspects in Movement Disorder Patients: Comparison Between Parkinson Disease and Spinocerebellar Ataxia Type 3.

To evaluate the orofacial myofunctional characteristics, masticatory performance and facial thermal profile in individuals with Parkinson disease (PD) and spinocerebellar ataxia (SCA3), comparing with healthy control ones. Seventy-two participants aged between 30 and 85 years were evaluated and divided into PD, SCA3 and control groups. The assessments included clinical evaluation using the Orofacial Myofunctional Evaluation with Scores protocol (orofacial structures, mastication, swallowing and breathing aspects), masticatory performance assessed with a colour-changeable chewing gum and infrared thermography. The Kruskal-Wallis, one-way ANOVA and Wilcoxon tests were applied. With the exception of face and tongue, a difference was seen in the cheek, maxillomandibular relationship, lips, mentalis muscle and palate appearance and posture between patients and healthy control participants. Orofacial mobility, swallowing and masticatory function also scored higher in the control group. The SCA3 and PD groups required more time to eat the test-food and showed greater facial temperature asymmetries than the control one (p < 0.05). Masticatory performance measured by chewing gum did not differ. Facial temperature asymmetries, swallowing and masticatory function scores and the time needed by the SCA3 and PD groups to eat the test-food were different from healthy participants, drawing attention to the impaired orofacial functions in patients with neurodegenerative disorders.

Predictors of Verbal Fluency Decline in People with Cognitive Dysfunctions

Background: Verbal fluency impairment is a prospective risk for dementia and conversion from Mild Cognitive Impairment (MCI) to dementia. In elderly may be related to the deficits in other cognitive domains and also with age and duration of cognitive decline. The AIM: The purpose of this study was to analyze the results of Verbal Fluency Tests (VFT) in people with cognitive decline in relation to age, duration of the cognitive decline and the level of cognitive dysfunction. Methods: 279 (177 females and 102 males) people with cognitive decline (MCI and dementia), aged 50-91 years were included in the study. For the evaluation of general cognitive abilities Mini Mental State Examination (MMSE) and for assessment of verbal fluency– Verbal Fluency Test (phonological and categorical) was applied. Statistical analysis was performed using nonparametric tests. Factor analysis of the main components of Verbal Fluency Test and MMSE were used and one-way ANOVA test in the prediction analysis was applied. Results: All dimensions of verbal fluency subscales and MMSE are explained by one factor, which indicate their similar etiological mechanism. The longer duration of the cognitive impairment the worse results in VFT and MMSE. Worse results of MMSE were associated with worse performance on VFT, the most important critical moment of deterioration was associated with scores in the range of 25-23 and 17-18 MMSE points, however there are some differences between verbal fluency categories. The most significant periods of duration of the disease for VFT performance were months 6 and 9, and for the category of categorical fluency months 6,9, as well as 26, 31-32 and 36. No significant associations between the age and VFT and MMSE results were observed. Conclusions: Verbal fluency decline is related to global cognitive functioning. Longer duration time of the disease was associated with the level of verbal fluency and cognitive decline, while the age of patients is not an important factor. The verbal fluency deterioration occurs in leaps and bounds, the critical moments for verbal fluency decline may be established based on the duration of the illness and global functioning measured by MMSE.

Assessment of Risk Factors for Women with Iron Deficiency Anemia During Pregnancy

Background: Globally, iron insufficiency is the most common nutrient deficiency and the primary cause of anemia. Iron deficiency can result in maternal anemia and decreased infant iron reserves due to increased iron demand during pregnancy. Objective: The study was designed to assess the risk factors encountered during pregnancy among pregnant women with iron deficiency anemia. Materials and Methods: The study was conducted on one hundred pregnant women enrolled on the health care centers who were diagnosed as anemic. The data were obtained from all through direct interviews using a special questionnaire covering the sociodemographic characteristics, diet habits, and supplements taken during pregnancy. The one-way ANOVA test analysis was done to see the association of each variable with the anemia severity. The probability value &lt;0.05 was considered statistically significant. Results: The results indicated that there was no statistically significant relation between iron deficiency anemia and all the socio-demographic characteristics which included; age, parity, educational level, occupation, family size, and gestational age. While there is a highly statistically significant relation between iron deficiency anemia and diet habit of pregnant women regarding the frequency of intake of meats, fishes, vegetables, and fruits at p-value = 0.001, intake pulse at p-value = 0.012, intake of nuts at p-value = 0.021, and drinking tea at p-value = 0.001. Conclusion: Educating pregnant women to eat iron-rich foods may be useful as a strategy for reducing iron deficiency anemia during pregnancy, also using of iron supplements, folic acid and vitamin B12 is regarded as a successful way to treat anemia.

An Assessment of Hepato-protective Activity of Hygrophila auriculata Root Extract against Hepatic Injured Rodent Model

Liver is a crucial organ that is susceptible to several hepatotoxins causing hepato-toxicities. These days, medicinal plants have been considered to be more promising compared with the conventionally utilized medications for hepatic treatments. In light of the dire circumstances affecting worldwide currently, Hygrophila auriculata is a vital plant with an abundance of health advantages and hepatoprotective properties. In this experiment, carbon tetrachloride (CCl4) was utilized to cause hepatotoxicity in rats and this plant's anti-hepatotoxic activity was evaluated through assessing the outcomes of several parameters (Liver functioning tests, kidney functioning tests and lipid profiles). Subsequent research revealed that the plant may, to varying degrees and in a dependent way, successfully restore the disrupted pathological state to healthy status. To interpret statistical analysis, the "One-way Anova test" was conducted using the SPSS 16 software. In the case of SGPT, the medium and high dose produced statistically significant (p&lt;0.05) outcomes as compared to the negative control group and for SGOT decrease in all three groups were non-significant (p&gt;0.05). Then for creatinine levels, the outcome for medium, and high dosages were statistically significant (p&lt;0.05) whereas in case of urea level only the high dose imparted significant (p&lt;0.05) decrease. However, none of the dosages for total cholesterol and triglyceride level produced statistically significant (p&lt;0.05) effects. Only in the medium and high doses, HDL levels improved statistically significantly (p&lt;0.05) whereas only the high dosages reduced reduce the LDL quantity in the blood significantly (p&lt;0.05). As a result, Hygrophila auriculata is thought to possess a significant capacity for liver protection and may serve as a more secure and effective substitute for the commercially available synthetic medication, silymarin. To sum up, additional research is required in the future before this appealing plant could get utilized in the arena of hepatotoxic treatments.

Latent profile analysis of empathy ability and its relationship with professional quality of life among hospice nurses in China

BackgroundEmpathy is important in hospice nursing clinics and may influence nurses’ professional quality of life (ProQOL). However, present studies ignoring each empathic dimension, and few researches have explored the correlation between empathy and ProQOL in hospice nurses in Asia. To better understand hospice nurses’ empathy abilities in China and its relationship with ProQOL, the aim of this study was to identify the latent profiles and its influencing factors of hospice nurses’ empathy ability, as well as differences in ProQOL across each latent profile.MethodsA cross-sectional study was conducted from October 2021 to September 2022, and a total of 725 hospice nurses were recruited from different geographic regions in China. Participants completed the Empathy Ability Scale for Hospice Nurses and the Brief Professional Quality of Life Scale. Latent profile analysis (LPA) was employed to identify latent profiles of empathy ability among hospice nurses in China. The predictors of hospice nurses’ empathy ability in different latent profiles were assessed using multinomial logistic regression analysis. One-way ANOVA test and the Kruskal–Wallis test were used to compare the ProQOL scores in each latent profile of nurses’ empathy ability.ResultsThis study identified three latent profiles of hospice nurses’ empathy ability, and those profiles labelled “poor empathy ability-high surface empathy expression” (n = 216, 29.8%), “moderate empathy ability” (n = 359, 49.5%) and “high empathy ability-high deep empathy expression” (n = 150, 20.7%). Multinomial logistic regression analysis suggested that age, hospital level, whether income meets expectations, interests in hospice care work, hospice work experience, and receiving psychological counselling were predictors of hospice nurses’ profile membership of empathy ability. The scores of compassion satisfaction (CS) and burnout (BO) in ProQOL were significantly different across each profile (P < 0.001), while scores of secondary traumatic stress (STS) in ProQOL were not different across each profile (P = 0.294).ConclusionsHospice nurses’ empathy ability was divided into three latent profiles, and enhancing empathy ability may be conducive to improving hospice nurses’ CS, while reducing BO, thus fostering their overall quality of life. Nursing managers should identify hospice nurses at higher risk of BO and implement targeted interventions focused on enhancing nurse’s empathy abilities.

A novel injectable boron doped-mesoporous nano bioactive glass loaded-alginate composite hydrogel as a pulpotomy filling biomaterial for dentin regeneration

BackgroundDifferent materials have been used as wound dressings after vital pulp therapies. Some of them have limitations such as delayed setting, difficult administration, slight degree of cytotoxicity, crown discoloration and high cost. Therefore, to overcome these disadvantages, composite scaffolds have been used in regenerative dentistry. This study aims to construct and characterize the physicochemical behavior of a novel injectable alginate hydrogel loaded with different bioactive glass nanoparticles in various concentrations as a regenerative pulpotomy filling material.MethodsAlginate hydrogels were prepared by dissolving alginate powder in alcoholic distilled water containing mesoporous bioactive glass nanoparticles (MBG NPs) or boron-doped MBG NPs (BMBG NPs) at 10 and 20 wt% concentrations. The mixture was stirred and incubated overnight in a water bath at 50 0 C to ensure complete solubility. A sterile dual-syringe system was used to mix the alginate solution with 20 wt% calcium chloride solution, forming the hydrogel upon extrusion. Then, constructed hydrogel specimens from all groups were characterized by FTIR, SEM, water uptake percentage (WA%), bioactivity and ion release, and cytotoxicity. Statistical analysis was done using One-Way ANOVA test for comparisons between groups, followed by multiple pairwise comparisons using Bonferroni adjusted significance level (p < 0.05).ResultsAlginate/BMBG loaded groups exhibited remarkable increase in porosity and pore size diameter [IIB1 (168), IIB2 (183) (µm)]. Similarly, WA% increased (~ 800%) which was statistically significant (p < 0.05). Alginate/BMBG loaded groups exhibited the strongest bioactive capability displaying prominent clusters of hydroxyapatite precipitates on hydrogel surfaces. Ca/P ratio of precipitates in IIA2 and IIB1 (1.6) were like Ca/P ratio for stoichiometric pure hydroxyapatite (1.67). MTT assay data revealed that the cell viability % of human gingival fibroblast cells have declined with increasing the concentration of both powders and hydrogel extracts in all groups after 24 and 48 h but still higher than the accepted cell viability % of (˃70%).ConclusionsThe outstanding laboratory performance of the injectable alginate/BMBGNPs (20 wt%) composite hydrogel suggested it as promising candidate for pulpotomy filling material potentially enhancing dentin regeneration in clinical applications.

Study on Trend of Immunization Coverage in Mutum Biyu Ward "B" From 2016-2019 in Gassol Local Government Area, Taraba State, Nigeria

This study examines the trend of immunisation coverage for Bacille Calmette-Guerin (BCG), Oral Polio Vaccine (OPV), Measles, and Yellow Fever in Mutum Biyu Ward 'B' of Gassol local Government Area, Taraba State, Nigeria, from 2016 to 2019. The DHIS2 Nigeria platform was used to gather secondary data using a quantitative, cross-sectional approach. In order to analyse the completion and non-completion rates of Routine Immunisation (RI) schedules, vaccination cards and carer recollection were the main sources of immunisation histories. One-way ANOVA testing and descriptive statistics were used in the data analysis. The study's findings showed that vaccination coverage varied over time. The BCG coverage saw notable fluctuations, peaking in the years 2017 and 2019. In 2018, OPV coverage rose on average but somewhat decreased. Measles vaccination rates were steady at first, then they fell in 20l8 and then sharply recovered in 2019. The vaccination rate for yellow fever was low in 20l6, improved slightly in 2017, declined sharply in 2018, and then reached its peak in 2019. The study recommended localized use of geo-mapping to identify and map communities with low immunisation coverage in Mutum Biyu Ward "B" of Gassol LGA, Taraba State.

Identifying the approach to financial sustainability: Navigating the complexities of earning and spending

This study provides insightful information about personal finance by examining the complex relationship between income and spending patterns in various occupations. It reveals strong relationships between income levels and expected results through regression analysis, providing insight into how different occupational groups are impacted by financial well-being. Building on this basis, a thorough one-way ANOVA and post-hoc tests show that students, academics, labourers, business owners, and government employees have remarkably different spending preferences. These results highlight the significant impact of occupation-specific variables on financial behaviour, including benefits, income stability, and social expectations. This research provides a path corresponding to specific policy interventions and programs aimed at financial literacy. By promoting economic resilience and well-being across a range of demographic and occupational landscapes, the ultimate objective is to cultivate a future in which responsible spending practices are shared realities rather than just ideals.

Potential Impact of Physical Activity on Measures of Well-Being and Quality of Life in People with Rare Diseases: A Nationwide Cross-Sectional Study in Italy.

Rare diseases constitute a heterogeneous group of approximately 7000-8000 conditions, distinguished by their low prevalence. Collectively, they present a significant global health challenge, affecting millions of people worldwide. It is estimated that rare diseases affect approximately 10% of the global population, which places a significant burden on individuals, families, and society. It is, therefore, important to consider strategies to improve the overall well-being and quality of life of individuals with rare diseases. One potential avenue for exploration is the incorporation of physical activity (PA). The scope of this study was to ascertain whether PA has a positive impact on measures of well-being and to determine its potential to enhance the quality of life of these individuals. The data were collected via an online survey. The one-way ANOVA test for multiple groups and multivariate Poisson models were employed to identify the significant predictors of the outcomes of interest. The protective effects of PA become evident with a minimum of six hours of activity per week. Our data confirm that the weekly hours devoted to PA can serve as a significant protective factor for QoL. The study also provided some insights into the motivations behind patients' engagement in PA. These included improving QoL and physical well-being, as well as the desire to interact socially, with the goal of meeting friends or making new acquaintances. Finally, for adults and older adults, engaging in PA can also be a way to control weight. It is becoming increasingly clear that individuals with rare diseases stand to benefit greatly from PA, so it is only sensible to educate them on the advantages of an active lifestyle.

Physicochemical and sensory quality of high antioxidant fruit leather of red dragon fruit and watermelon rind enriched with seaweed

Fruit, as a source of antioxidants and phenolic compounds, is perishable. It also has an underutilized component. Fruit leather has a long shelf life in the form of thin sheets with a distinctive texture. This study aimed to investigate the effect of seaweed (Eucheuma cottonii) addition on the physicochemical and sensory quality of fruit leather made from the combination of red dragon fruit and watermelon rind. The physicochemical quality was characterized by measuring the critical quality parameters of fruit leathers, including proximate analysis, water activity, total phenol, antioxidant activity, texture, and organoleptic analysis. The statistical analysis of phenolic compound activity, antioxidant activity, vitamin C, moisture content, carbohydrates, and water activity (aw) was conducted using a one-way ANOVA test, while the analysis of ash content, protein, fat, tensile strength, elongation, and organoleptic properties was performed using the Kruskal–Wallis test. Increasing seaweed concentration significantly increased moisture, ash, protein, vitamin C, total phenol, water activity, and elongation but decreased fat content. Furthermore, the increase in seaweed concentration reduced liking toward taste and color significantly but increased texture liking. The best product was the F2 product with 10% seaweed. F2 has the following attributes: 11.07% of moisture content, 2.34% of ash, 1.53% of protein, 0.19% of fat, 84.86% of carbohydrate, 8.17 mg/100 g of vitamin C, 0.41 of water activity, 0.54 N/m2 of tensile strength, 22.22% of elongation, 107.39 ppm of IC50, 1.66 mg/GAE g of total phenolics.

FDA-approved PDE4 inhibitors alleviate the dominant toxicity of ALS-FTD-associated CHCHD10S59L by reducing the PINK1/Parkin pathway.

Mutations in coiled-coil-helix-coiled-coil-helix domain containing 10 (CHCHD10) have been identified as a genetic cause of amyotrophic lateral sclerosis and/or frontotemporal dementia(ALS-FTD). In our previous studies using in vivo Drosophila model expressing CHCHD10S59L, and human cell models expressing CHCHD10S59L, we have identified that the PINK1/Parkin pathway is activated and causes cellular toxicity. Furthermore, we demonstrated that pseudo-substrate inhibitors for PINK1 and mitofusin2 agonists mitigated the cellular toxicity of CHCHD10S59L. Evidences using in vitro, in vivo genetic, and chemical tools indicate that inhibiting PINK1 would be the most promising treatment for CHCHD10S59L-induced diseases. An in vivo human cell culture and in vivo Drosophila models expressing CHCHD10S59L mutant were utilized in this study to evaluate the effect of PDE4 inhibitors in PINK-parkin mediated cytotoxicity through immunohistochemical and seahorse assays. Data were analysed using one-way ANOVA and post-hoc Dunnett's test for statistical significance. We investigated cellular pathways that can modulate the PINK1/Parkin pathway and reduce CHCHD10S59L-induced cytotoxicity. Here, we report that FDA-approved PDE4 inhibitors reduced CHCHD10S59L-induced morphological and functional mitochondrial defects in human cells and an in vivo Drosophila model expressing C2C10HS81L. Multiple PDE4 inhibitors decreased PINK1 accumulation and downstream mitophagy induced by CHCHD10S59L. These findings suggest that PDE4 inhibitors currently available in the market may be repositioned to treat CHCHD10S59L-induced ALS-FTD and possibly other related diseases, and that disease treatment with PDE4 inhibitors should include careful consideration of the PINK1/Parkin pathway, as it is generally recognized as a protective pathway.

Accounting issues in Calculating Taxes on Corporate Entities revenue of Entrepreneurs in Luang Prabang Municipality, Luang Prabang Province

In this study, the research team studied the accounting issues in calculating tax on corporate entities’ revenue of entrepreneurs in Luang Prabang Municipality, Luang Prabang Province. The purposes are to study the level of accounting problems in calculating the corporate income tax of entrepreneurs. To compare the level of accounting problems in calculating the corporate income tax of entrepreneurs by individual factors, the population used in the research was the accounting staff or entrepreneurs who calculated the corporate income tax of the business entities registered with the enterprises, a simple number of randoms 254 totally. The statistics used in the data analysis included descriptive and parameter reference statistics with the following values: frequency, percentage, mean, standard deviation, one-way ANOVA test, and paired test by LSD method. The results of the research were as follows: 1) The level of accounting problems in calculating the corporate income tax of business entities is as follows: Overall, it is at a moderate level which analyzed each aspect is sorted from large to small: the calculation of the depreciation of property prices in several levels, the improvement of accounting expenses tax is at a moderate level and the improvement of accounting income to a tax at a moderate level. ( 2 ) Comparison of the level of accounting problems in calculating the corporate income tax of entrepreneurs by classification according to personal factors such as classified by level of education found entrepreneurs there are different levels of education in accounting problems in calculating the corporate income tax varies two aspects are to improve the accounting expenses to be tax and to improve the accounting income to be tax and to classify according to the work experience of the entrepreneur found entrepreneurs with different work experience there are accounting problems in calculating the corporate income tax varies two aspects are the adjustment of accounting expenses to tax and the calculation of the depreciation of property prices.

Comparative clinical study of Mist Amen Fevermix and Edhec Malacure: two polyherbal products used for the treatment of uncomplicated malaria in Ghana against Artemether/Lumefantrine

The use of herbal products for the treatment of malaria, has increased globally. However, inadequate scientific studies about the safety and effectiveness of such herbal products have been raised. Also, the reduced sensitivity of the malaria parasites to artemisinin-based combination therapies is of concern. There is therefore the need for new antimalarial medications including those from alternative sources such as herbal medicinal products. In this study, a prospective, comparative parallel group randomized, clinical study was done to assess the safety and effectiveness of Mist Amen Fevermix and Mist Edhec Malacure with Artemether/Lumefantrine as control at the Tafo Government Hospital, Kumasi between July and November 2019, after Committee on Human Research, Publication and Ethics approval (CHRPE/AP/424/19). The study was conducted in accordance with Good Clinical and Laboratory Practice (GCLP) and registered with the Pan African Clinical Trials Registry with trial number PACTR202109664146698. Participant completed an informed consent form. Randomization was based on a single sequence to allocate participants to a group. SPSS version 19. One-way ANOVA test and exploratory statistics was used for data analysis. Total sample size was 150 participants with 50 on each arm of the group. Male and female patients aged 15–45 years and meet inclusion criteria with clinically established malaria were treated with Mist Amen Fevermix and Mist Edhec Malacure, at the specified doses of 45 mls (0.1063 g) and 30 mls (0.0521 g) three times daily after meals for three days. Artemether/Lumefantrine was administered at a dose of 80/480 mg/kg twice daily after meals for three days. Baseline data was taken on day 0. Patients were then followed up on Day 3, 7 and 28 to establish treatment outcomes and any side effect using a checklist for signs and symptoms and Karnofsky’s scale to assess the quality of life. Mist Amen Fevermix was effective with a cure rate of 95.89%. Mist Edhec Malacure was also effective with a cure rate of 91.87%. The cure rate of Artemether/Lumefantrine was 97.25%. Kidney and liver panels were within normal reference range at the end of the 28-day study. This study supports the use of Mist Amen Fevermix and Mist Edhec Malacure, two multi-component products as safe and effective for the treatment of uncomplicated malaria. Both products achieved a comparable clinical treatment outcome with Artemether/Lumefantrine.

Comparison of barriers to physical activity to levels of physical activity and psychological well-being based on the demographic environment in the vision impairment disability group

Barriers to physical activity in vision impairment are associated with increased inactivity and psychological well-being problems. Previous research has only identified constraints in physical activity without conducting an in-depth analysis of physical activity levels and psychological well-being. This study aims to explore the differences in physical activity barriers based on three different demographic environments regarding physical activity levels and psychological well-being. The method used was quantitative inferential with a cross-sectional design approach involving 90 respondents registered with the Indonesia Association of the Blind. Data were collected using the Barrier Questionnaire for People with Vision Impairment (BPAQ-VI), the Psychological Well-Being Scale (PWBS), and General Practice Physical Activity (GPPAQ). The data was processed using the one-way ANOVA test and the Tukey HSD via SPSS version 26. The study's results stated differences in physical activity barriers, physical activity levels, and psychological well-being in vision impairment groups living in urban centres, suburbs, and rural areas (p&lt;0.05). It was concluded that the visionly impaired disability group living in the city centre had minimal barriers compared to the vision impairment group living in suburban and rural areas. Vision impairment groups living in urban centres have better physical activity and psychological well-being than those living in suburbs and rural areas. The study contributed to an increase in the number of fitness influencers among those with vision impairment. It raised awareness among sports practitioners to design innovative and friendly exercise methods and programs for the group. Keywords: Barrier Physical Activity, health, fitness and wellness, environment, psychological well-being, blind.

Comparison of the Antimicrobial Efficacy of Conventional Versus Chitosan Re-inforced Heat-Polymerized Polymethylmethacrylate Dental Material: An In Vitro Study.

Polymethylmethacrylate (PMMA) is widely used in the fabrication of dentures due to its aesthetic appeal and mechanical strength. However, PMMA's susceptibility to microbial colonization often leads to oral infections such as denture stomatitis. Enhancing the antimicrobial properties of denture materials is crucial for improving patient outcomes.Chitosan, a natural biopolymer, possesses inherent antimicrobial properties and could potentially enhance the microbial resistance of PMMA. This study has investigated thepotential of chitosan-reinforced heat-polymerized PMMA denture material to reduce microbial colonization. The aim of the study was to evaluate and assess the anti-bacterial and antifungal properties of chitosan-reinforced heat-polymerized PMMA with conventional heat-polymerized PMMA Materials and methods:Chitosan-reinforced PMMA samples were fabricated with varying chitosan concentrations (0% control, 5%, 10%, and 15% by weight). The fabrication involved mixing chitosan powder with PMMA powder, adding monomer liquid, followed by mixing, packing, and curing using the conventional heat polymerization technique. The antimicrobial efficacy was assessed in vitro using two common oral pathogens: Streptococcus mutans and Candida albicans. Blood agar plates were used for S. mutans and Sabouraud agar plates were used for C. albicans. Each sample was placed on the respective agar plates inoculated with a standardized microbial suspension and incubated at 37°C for 24 hours. The number of colony-forming units (CFUs) was counted to quantify microbial growth. Statistical analyses, including linear regression analysis, one-way ANOVA test, and Pearson correlation were performed to evaluate the relationship between chitosan concentration and antimicrobial efficacy. The p-value was calculated to determine the statistical significance of the results. The chitosan-reinforced PMMA samples showed significantly greater antimicrobial efficacy compared to the conventional PMMA samples. The CFU counts for both S. mutans and C. albicans decreased with increasing chitosan concentration. Linear regression analysis indicated a strong negative correlation between chitosan concentration and CFU counts, with Pearson correlation coefficients of -0.97 for S. mutans and -0.98 for C. albicans. ANOVA analysis revealed a statistically significant difference in antimicrobial efficacy across different chitosan concentrations (p < 0.001). Incorporating chitosan into heat-polymerized PMMA significantly enhances its antimicrobial properties against S. mutans and C. albicans. The antimicrobial efficacy improves with higher concentrations of chitosan, with the 15% chitosan-reinforced samples showing the most substantial reduction in microbial growth. These results suggest that chitosan-reinforced PMMA dentures could be a superior alternative to conventional PMMA dentures, potentially reducing denture-related infections and improving oral health outcomes for denture wearers.

The Effect of Using Gamification to Improve EFL Students' Academic Performance

This paper aims to determine whether there is evidence that gamified instruction can be effective in improving EFL students' academic achievement. The aim of the research is to establish how effective gamification is as a method against more traditional types of education and what areas of the English language—for example, reading comprehension, grammar, and vocabulary—are most effectively promoted via the integration of gamification into the classroom environment. The sample included 120 fourth graders from public schools in Jordan, where 60 children were to form the gamified instruction group and another 60 to form the standard instruction group. Pretests and posttests of English language skills using standardized tools measured students at two different times: before and after the instructional interventions. These tests are the main instruments utilized for data collection and analysis. Independent t-test, one-way ANOVA, and one-way MANOVA tests were performed to test the variation and holistic impact of the instructional methods on different components of language learning. The experimental findings support that the gamified instruction group scored significantly higher than the regular instruction group at post-intervention. More specifically, the students of the game-based group scored an average of 74.44 (SD= 7.93) on the posttest, compared to 69.31 (SD = 6.14) for those of the control group.The result for the T-test yields t = 4.05 and p &lt; 0.001, hence showing that the gamified group had significantly better results. The classroom gamification usage made noteworthy gains in students' vocabulary, grammar, and reading comprehension abilities. One-way ANOVA results were vocabulary, F = 22.65, p &lt; 0.001; grammar, F = 15.78, p &lt; 0.001; and reading comprehension, F = 18.93, p &lt; 0.001. MANOVA supported this finding that the Wilks' Lambda value was 0.62, with an F-value of 20.45 and a p-value less than 0.001, indicating that gamified training was of benefit overall in enhancing English language competence. The results of this research come with a very exciting revelation, such as gamified instruction being an excellent means of teaching English as a foreign language since it enhances students' interest and performance in class.

The Effect of Using Gamification to Improve EFL Students' Academic Performance

This paper aims to determine whether there is evidence that gamified instruction can be effective in improving EFL students' academic achievement. The aim of the research is to establish how effective gamification is as a method against more traditional types of education and what areas of the English language—for example, reading comprehension, grammar, and vocabulary—are most effectively promoted via the integration of gamification into the classroom environment. The sample included 120 fourth graders from public schools in Jordan, where 60 children were to form the gamified instruction group and another 60 to form the standard instruction group. Pretests and posttests of English language skills using standardized tools measured students at two different times: before and after the instructional interventions. These tests are the main instruments utilized for data collection and analysis. Independent t-test, one-way ANOVA, and one-way MANOVA tests were performed to test the variation and holistic impact of the instructional methods on different components of language learning. The experimental findings support that the gamified instruction group scored significantly higher than the regular instruction group at post-intervention. More specifically, the students of the game-based group scored an average of 74.44 (SD= 7.93) on the posttest, compared to 69.31 (SD = 6.14) for those of the control group.The result for the T-test yields t = 4.05 and p &lt; 0.001, hence showing that the gamified group had significantly better results. The classroom gamification usage made noteworthy gains in students' vocabulary, grammar, and reading comprehension abilities. One-way ANOVA results were vocabulary, F = 22.65, p &lt; 0.001; grammar, F = 15.78, p &lt; 0.001; and reading comprehension, F = 18.93, p &lt; 0.001. MANOVA supported this finding that the Wilks' Lambda value was 0.62, with an F-value of 20.45 and a p-value less than 0.001, indicating that gamified training was of benefit overall in enhancing English language competence. The results of this research come with a very exciting revelation, such as gamified instruction being an excellent means of teaching English as a foreign language since it enhances students' interest and performance in class.

Students’ Perceptions of Workplace Robots in the Republic of Serbia

Research Question: The key research question is what the key positive and negative perceptions of students from the Republic of Serbia regarding workplace robots are. Motivation: Academics, practitioners, and decision-makers are more and more interested in the impact of new technological solutions in the field of robotics on organizations and their functioning. Ongoing technological advancements have accelerated the adoption and use of robots in the workplace. As a result, organizations that plan to introduce robots should consider all effects on employees, both positive and negative. Idea: The main idea is to examine and analyse the perceptions and attitudes of students from the Republic of Serbia regarding robots at the workplace. The results of this study regarding students' perceptions and attitudes towards robots in the workplace are crucial for the future of work and job design. Data: Data were collected via online questionnaire consisting of five profile questions and 13 statements organized in two five-point Likert scales. From January to March 2023, the questionnaire was completed by 164 students from the Republic of Serbia. Tools: The collected answers were analysed using the Statistical Package for Social Sciences – SPSS, version 21.0. (Armonk, NY: IBM Corporation). The Cronbach's Alpha coefficient, Kolmogorov-Smirnov test, descriptive statistics, student t-test and one-way ANOVA test was used for data analysis. Findings: Research results showed that most respondents believe that robots can do dangerous jobs that humans cannot, that robots can free humans from routine and monotonous jobs, and that humans will have more time for creative tasks. Robots in the workplace, on the other hand, will have some negative consequences. Many respondents agree that working with robots without people would make them feel lonely; robots would not know how to react in some unexpected circumstances; and they are not as flexible and mobile as humans. Contribution: The findings of this study could make a significant contribution to a better understanding of students’ attitudes towards robots in the workplace and they may help decision makers, employers, leaders, and managers on how to increase workplace acceptance of robots.