Operational parameters in true triaxial loading devices (TTA), such as the loading rod dimensions, friction between the loading platens and sample faces, loading gap, and one-side loading may affect the test results. Knowledge of the effect of each parameter is very important to correctly interpret rock behavior and to optimize these devices. Employing the Flac3D finite difference software, a rigid type true triaxial systemdesigned and builtat Amirkabir University of Iran (AUT-TTA) was simulated andinvestigated in this study. The results indicate that increasing the ratio of the rod cross-section to the loading platen area leads to an increase in the sample confinement, so, more uniform stress distribution occurs in the rock sample. The loading gap reduces strength of the rock specimen and leads to concentration of tensile stresses at the sample edges. The end effect leads to an increase in the stress level and a pseudo-hardening behavior in the samples. Also, the end effect is intensified under one-side loading condition compared to two-side loading. Comparison between results of AUT-TTA numerical simulation and analytical analysis (ideal conditions without considering operational parameters) indicates that the slope of the stress–strain diagram has low sensitivity to operational parameters. The most important operational factor affecting the stress level and dilatation stress is the end effect and other operational parameters have little effect. All parameters lead to an increase in the dilation strain. The clear edge and one-sided loading under low intermediate principal stresses and the end effect under high intermediate principal stresses have the greatest effect on the dilation strain.