One-Pot Synthesis Of Ketones Research Articles

Direct Synthesis of Ketones from Primary Alcohols and 1-Alkenes

Two consecutive catalytic reactions, the oxidation of a primary alcohol by hydrogen transfer and the subsequent intermolecular hydroacylation in the presence of 2-amino-4-methylpyridine (AMP), take place in a generally applicable one-pot synthesis of ketones from primary alcohols and 1-alkenes catalyzed by transition metals [Eq. (a)]; R = aryl, R′ = alkyl.

Use of (±)-isopinocampheyldichloroborane for the efficient synthesis of unsymmetrical ketones via stepwise hydroboration of alkenes

A convenient, one-pot synthesis of unsymmetrical ketones has been developed making use of the in situ reduction — hydroboration reactions of readily prepared and stable (±)-isopinocampheyldichloroborane.

One-Pot Synthesis of Unsymmetrical Ketones by the Reaction of Decacarbonyldimanganese with Two Kinds of Alkyllithiums

Abstract Decacarbonyldimanganese (Mn2(CO)10) is utilized as a phosgene equivalent for the one-pot preparation of unsymmetrical ketones. By a successive treatment of Mn2(CO)10 with two kinds of alkyllithiums, unsymmetrical ketones are obtained in high selectivity. Unsymmetrical α-diketones are generated when the above reaction is carried out in the presence of trimethyl phosphite and is quenched with N-bromosuccinimide.

Cobalt-catalysed three-component coupling involving ketones or ketoesters, aldehydes and acetonitrile: a novel one-pot synthesis of β-acetamido ketones

Cobalt(II) chloride catalyses one-pot coupling of ketones or ketoesters, aldehydes and acetonitrile in the presence of acetyl chloride to give β-acetamido ketones 3 in good yields.

ChemInform Abstract: A One‐Pot Synthesis of Ketones and Aldehydes from Carbon Dioxide and Organolithium Compounds.

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

Desilylation and Michael addition reactions of (trimethylsilyl)ethynyl ketones: a novel one-pot synthesis of enamine ketones, bis(enamine ketones), and poly(enamine ketones)

Desilylation and Michael addition reactions of (trimethylsilyl)ethynyl ketones: a novel one-pot synthesis of enamine ketones, bis(enamine ketones), and poly(enamine ketones)

α-Lithio trimethylsilylmethyl lithium carbonate as methanol dianion synthon. A one-pot synthesis of α-hydroxy ketones.

1-Trimethylsilylmethanol is used via its lithiated lithium carbonate in a one-pot procedure to hydroxymethylate esters, dimethylamides, acid chlorides and nitriles to give the corresponding hydroxymethyl carbonyl compounds in the synthetic conversion RCOX → RCOCH 2OH.

One-pot synthesis of ketones from carboxylic acids and grignard reagents using N,N-Diphenyl-p-methoxyphenylchloromethyleniminium chloride

N,N-Diphenyl-p-methoxyphenylchloromethyleniminium chloride is found to be an effective condensation reagent of carboxylic acids and Grignard reagents under mild conditions to afford the corresponding ketones in high yields.