One-factor Analysis Of Variance Research Articles

Analysis of the Somatic Cell Pattern in Mastitis - Affected Cows on Three Dairy Farms in Vojvodina

Summary Somatic cells (SCs) in milk, which include epithelial cells from the gland and blood cells, are present in milk during the normal course of milking. Increase in SCs is found in mastitis-affected dairy cows and can be a useful indicator for estimating mammary health and milk quality worldwide. The aim of this study was to determine whether there was a pattern of somatic cell count (SCC) in mastitis-affected cows on three different farms. The study was conducted on three dairy farms of high milk-producing cattle breeds in Vojvodina during 2021. Samples were taken from 15 cows from each farm, all of the cows being diagnosed with clinical and subclinical mastitis. The SCC in milk samples was determined by the microscopic reference method according to the standard (SRPS EN ISO 13366-1:2010) of the Institute for Standardization of Serbia. The value of SCC was considered as high if >200.000 cells/mL, as this is the threshold indicating secretion disorder. In order to examine the differences between the observed three farms, one-factor analysis of variance (ANOVA) was applied, while a post-hoc LSD test was used for determination of statistically significant differences between the SCC in cows on three different farms. The mean values of the SCC on Farms 1, 2 and 3 were 7,055,266.67, 2,619,893.33 and 552,000 cells/mL, respectively. Based on the results, a statistically significant difference (p<0.05) was established between Farms 1 and 2, as well as between Farms 1 and 3, while there was no statistically significant difference between Farms 2 and 3. Apart from mastitis, differences in the SCC on the farms could also be influenced by the cows’ productivity, parity, lactation stage and breed, as well as poor management practices. Besides mastitis control, better hygiene and proper nutrition can help in reducing SCs in milk. In conclusion, establishing SCs pattern can provide useful information that may contribute to reducing SCs and developing differential SCs standards to help obtain milk with low SCs and consequently better dairy products with a longer shelf life.

Factors and their influence on the indicators of milk productivity of first-born of Ukrainian dairy breeds

The article examines the influence of genotypic factors on the formation of milk productivity indicators in first-born cows of various breeds. Genotyping of 744 cows of Ukrainian Brown Dairy, Ukrainian RedAnd White, Ukrainian Black-and-White Dairy breeds and Sumy inbred type of Ukrainian Black-and-White dairy breed, which are kept in breeding farms of State Enterprise "Experimental Farm of Institute of Agriculture of Northern East of NAAS" of Sumy district of Sumy Region and PRAE Ichnyanske and PRAE Khliborob of Chernihiv region. In order to determine the polymorphism of the beta-casein gene, genetic studies were carried out in the laboratory of Institute of Physiology named after Bogomolets of NAS with the help of molecular biological analysis of allele recognition by polymerase chain reaction (PCR) in real time. The study of milk productivity indicators was carried out with the help of generally accepted methods, using the electronic database of SUMS "Orsek". The influence of genotypic factors was determined based on the results of one-factor variance analysis. Between animals of different breeds, there is a significant difference in the influence of genotypic factors on indicators of milk productivity. Linear belonging had a statistically significant effect on milk yield and the content of fat and protein in milk in animals of the Ukrainian black-and-white and redand-white dairy breeds. Whereas in cows of Ukrainian brown dairy breed - only on the amount of milk yield. In first-borns of Sumy intrabreed type, linear belonging did not have a statistically significant effect on the studied indicators. Father's origin has a much greater influence (ή2,=22-62 %). The genotype of the animal according to beta-casein actually does not have a reliable effect on the indicators of milk productivity. However, in animals of Ukrainian red-and-white dairy breed and Sumy inbred type of Ukrainian black-and-white dairy breed, it reliably influenced the formation of milk yield and fat content in milk. Therefore, with the aim of forming the desired value of milk productivity traits in first-born cows, the primary task is to carry out the selection of breeders assessed for the quality of the offspring of the corresponding lineal affiliation. Key words: genotype, beta-casein, influence, milk productivity, breed

Assessment of morphological features of skin and hair cover of Karakul lambs (South of Kazakhstan).

The relevance of the present research is related to the great importance of Karakul sheep breeding in Kazakhstan and the insufficient investigation of morphological features of the skin and hair cover of Karakul lambs in modern literature. The purpose of the research was to explore the specific features of hair pigmentation and histological structure of the skin of Karakul lambs of different colour groups: black, sur, grey, and brown. The work involved the standard methods of assessing the pigment content in the hair of lambs and methods of histological studies. The study utilised statistical methods including the Kolmogorov-Smirnov criterion, one-factor analysis of variance, Fisher's F-criterion, and the Bonferroni method, with data processed through the "PASW Statistics 17" and "Statistica 6.0" software packages. The results of the research demonstrate that the pigment content in the hair of new-born Karakul lambs depends on their colouring. Differences in pigment precipitation between different colour groups of lambs were established: pigment grains in black hairs and suras were larger, in comparison with brown and grey hairs, in which pigment was represented by the smallest grains. At the age of 19days, no significant changes in the colouring of the lambs examined were found (p > 0.05), whereas on reaching 4months of age, depigmentation (p < 0.05) was noted in all colour groups, which was slower in black lambs.

Multivariate analysis of the parameters of the immune response after immunization with inactivated influenza vaccines

Influenza A and B viruses are widely spread respiratory pathogens of humans and cause both isolated cases and local outbreaks of the disease, as well as massive seasonal epidemics and pandemics. Vaccination is the main strategy for combating influenza, and an increase in the proportion of vaccinated people in the population determines the success of vaccination. To identify patterns of postvaccination immune response formation to different types of vaccines and assess the significance of its multiple parameters the appropriate statistical methods should by applied. These methods allow to operate with large datasets and reduce their dimension, while keeping the maximum of information about the differences between individual observations. The aim of our study was the analysis of parameters of humoral and cellular immunity and their dynamics after vaccination with different types of inactivated influenza vaccines (IIV) using statistical methods of complex data analysis. The study was conducted in the clinical department of the Smorodintsev Research Institute of Influenza, Ministry of Health of the Russian Federation, in the flu season 2018 – 2019. The multivariate analysis of the immune response parameters after immunization with IIV “Grippol plus”, “Sovigripp” “Ultrix” included data obtained for 39 volunteers before vaccination, on the 7th and 21st days after vaccination. To identify parameters with significant differences between groups, one-factor analysis of variance (ANOVA) was used separately for each parameter and time point. To visualize the differences in the parameters selected in the analysis of variance, the Principal component analysis (PCA) method was used. The conducted studies revealed the peculiarities of the formation of a post-vaccination immune response to various types of IIV. It was shown that the factors of antigen-specific CD4+ and CD8+ T-cell immune response introduced the major contribution to the formation of the differences between groups. The approach is a powerful tool in analyzing the parameters of the immune response in clinical trials of influenza vaccines and other preventive medicine.

Erratum: High-Throughput Identification of Resistance to Pseudomonas syringae pv. Tomato in Tomato using Seedling Flood Assay.

Erratum: High-Throughput Identification of Resistance to Pseudomonas syringae pv. Tomato in Tomato using Seedling Flood Assay.

Development of a Biodegradable Material with Oregano Stick as a Prototype of Substitute for Wooden Agglomerate Material

Oregano is a herb that is found in the wild in different parts of the world. The stick represents about 60% of the plant and is biodegradable, using lactic acid as a binding agent for the oregano stick. Waste oregano stick can be used to make biodegradable material which provides sustainable development in support and promotion of the circular economy by reducing pollution generated by chemical economy by reducing pollution generated by chemical products, agricultural waste, or products that accumulate in the environment spending years for its degradability. The originality of this project is present in the use of the oregano stick, a natural product which supplies the physicochemical characteristics of conventional raw materials used in the manufacture of wood. Oregano was collected and dried to separate the leaves from the stick. The stick was then ground, sieved at 0.118 mm and 0.025 mm, and then treated with one of two binders. For treatment 1, three samples were prepared with varying lactic acid concentrations and stick quantities with the addition of 0.3 mL of 2,2 azobisiso-butyronitrile (AIBN) 1% by weight. In treatment 2, three samples were prepared with varying polyvinyl acetate concentrations, diluted in acetone, stirred, poured into a mold, and placed in an oven at a temperature of 90 °C for 36 h. Bending and compression mechanical tests were performed on all samples; the data were analyzed by one-factor analysis of variance and Tukey test. The sample that performed the best had a value of 1.148 mm and 0.77333 kN in mechanical resistance and less elongation in compression. This sample also had a value of 0.8183 and a kN of 0.1559 with a lower mean, meaning higher resistance to bending. This sample also had the best results from the Modulus of Rupture (MOR) test with a value of 5.9958 MPas/m2.

Pedagogical Conditions for the Training of Future Teachers Based on Digital Educational Technologies

This study aimed to assess the pedagogical frameworks for developing future teachers using digital education technology. The mixed-methods design, which combines quantitative and qualitative approaches, was employed to develop this study. Three hundred seventeen teacher candidates who are enrolled at several universities in Kazakhstan make up the research team. The researchers created a semi-structured interview form and an attitude scale toward digital technology in order to gather research data. The data was determined to be regularly distributed. Therefore, descriptive statistics, the T-test, and one-factor analysis of variance (ANOVA) tests were employed to assess them. The descriptive analysis method was applied to study the research’s qualitative data. The study’s findings showed that most pre-service teachers who took part in it thought that teacher training programs based on digital technology had adequate pedagogical conditions. Based on its results, the study offers recommendations.

The Comparison of Empathy and Self-Confidence Levels of Physical Education and Sports School Students

This study aims to compare the empathy and self-confidence levels of the students studying at physical education and sports schools according to different variables. In this study, the scanning model, which is one of the quantitative research designs, was used. Students were administered the empathy scale developed by Lawrence et al. and the self-confidence scale adapted by Akın. Our study was applied to four hundred students studying at Batman University School of Physical Education and Sports. The obtained data were analyzed in the SPSS program and the findings were interpreted. In the program, primarily descriptive statistics were used to indicate demographic characteristics and an unrelated sample t-test was applied to determine whether there was a significant difference between self-confidence and empathy levels and the variables of gender and whether they were involved in sports or not. One-factor analysis of variance (Anova) test was performed to determine whether there was a significant difference between self-confidence and empathy levels and age, department, grade level, grade point average, and sports branch of interest. As a result of the study, it was found that there was a significant difference between the empathy levels of the participant students and the gender and class variable. It was observed that there was no significant difference between students&amp;rsquo; empathy levels and age, students&amp;rsquo; academic grade point average, whether they did sports or not, and the sports branches they were interested in. It has been observed that there is no significant difference or relationship between students&amp;rsquo; self-confidence levels and gender, age, grade point average, sports status, and sports branches they are interested in. However, there was a significant difference between students&amp;rsquo; self-confidence levels and the department they studied. It is also seen that there is a significant difference between the self-confidence levels of the students and the variable of the class they study.

THE INFLUENCE OF THE TYPE OF FOREST AND THE TYPE OF FOREST GROWING CONDITIONS ON THE STABILITY OF SPRUCE STANDS IN THE ZONE OF CONIFEROUS-DECIDUOUS FORESTS OF THE PERM KRAI

There has been a massive drying out of spruce plantations in recent years. Many versions about the cause of this phenomenon have been put forward by scientists. Despite the active study of the problem of drying out of spruce plantations around the world, a forest management system aimed at reducing the damage from drying out has not been developed yet. Important silvicultural indicators of plantations that can affect their stability are the type of forest growing conditions and the type of forest. The purpose of the study was to establish the influence of the type of forest and the type of forest growing conditions on the resistance to drying out of spruce forests growing in the zone of coniferous-deciduous forests of the Perm Krai. The spruce forests of this territory were the objects of study. The sanitary condition of spruce forests growing in common types of forest growing conditions (B2, C2, C3) and forest types (green moss spruce and pine forest, wood sorrel spruce and pine forest, linden spruce and pine forest, grass spruce and pine forest) of the Perm Krai was determined. The weighted average scores values of the sanitary condition of the spruce forest of the surveyed forest plantations were distributed by forest types and types of forest growing conditions. Statistical indicators of the average weighted scores of the sanitary condition of spruce in different types of forests were obtained. A one-factor analysis of variance was carried out to compare the mean values. It was established that the type of forest and the type of forest growing conditions have an impact on the sanitary condition of spruce stands. The better the forest growing conditions, the more resistant the spruce trees are to drying out, on average. At the same time, soil moisture is more important than soil nutrient status.

Clinical Justification for Preliminary Thermal Exposure to Composite in the Treatment of Caries: Randomized Clinical Trial

Background. Polymer composites have good aesthetic characteristics and pronounced physicochemical properties, as compared to traditional restorative materials such as amalgam. However, the polymerization reaction of composite material containing bismethacrylate group commonly used in clinical practice is always accompanied by a different degree of volumetric shrinkage (2.7%~7.1%). The resulting stress can lead to adhesion failure and some other unfavorable clinical consequences, such as enamel destruction, microcracking of composite material and formation of microleakage between composite and tooth cavity wall, which can result in recurrent caries and postoperative sensitivity, thereby affecting the long-term effect of restoration. Therefore, studying the effect of preheating on composite restoration is important for its clinical application. Objective. To improve the effectiveness of treatment of patients with dental caries by improving the physicochemical properties of composite restorations.Methods. A randomized clinical trial enrolled 180 patients aged 18 to 45 years, diagnosed with dentin caries class I, according to Black (K02.1 in ICD). The study was conducted in the Dental Clinic of Kuban State Medical University, Russia. 180 composite restorations were performed in the treatment of dentin caries of molars. Patients were randomized into 2 groups): the control group — 90 patients and the main group — 90 patients. The control and main groups, in turn, were divided into three subgroups, depending on the composite used — Estelite Sigma Quick (Tokuyama Dental, Japan), Filtek Bulk Fill Posterior Restorative (3M Espe, USA) and DentLight (VladMiVa, Russia). Each subgroup consisted of 30 patients. In the control group, the classical method of filling with a composite material at “room temperature” was applied. In the main group, a composite heating conditioner “Ena Heat” (Micerium, Italy) was used to heat the composite to 55 °C before adapting the material in the formed cavity with subsequent photopolymerization. The quality of composite restorations within the clinical study was evaluated using the modified Ryge criterion immediately after treatment and after 6, 12, 18, 24 months. Statistical processing of the obtained data was carried out by means of one-factor analysis of variance using the GraphPadPrism 9 program (GraphPad Software, USA).Results. The duration of the clinical study comprised 24 months. The study revealed a statistically significant decrease in the quality of marginal fit of composite restorations (according to the Ryge score) by 20.1% (p = 0.0001) in the control group and by 5.7% (p = 0.0328) in the main group. At the same time, no statistically significant changes in Ryge scores were reported in the subgroups of composite materials of the main group (pF = 0.9480, pE = 0.1837, pD = 0.2529). As a result of the study, an optimal time algorithm (7 seconds) for using a special furnace for preheating the composite before sealing with subsequent photopolymerization was obtained.Conclusion. The study revealed a statistically significant positive effect of the proposed algorithm for working with a heated composite on the quality of marginal fit in the long term after treatment in comparison with the classical method of working with a composite at “room temperature”.

Измерение риска религиозной радикализации молодежи: конструкт и опросник

Introduction. The study of religious radicalisation is an important aspect of counteracting the incitement of hostility between different groups and communities and reducing the level of violence in Russian society. Modern scientific ideas are characterised by multiple meanings that do not effectively counteract the negative impact on young people’s attitudes towards religion and the believers. Academic literature describes concepts and models of radicalisation that differ in theoretical and methodological foundations, based mainly on the material of foreign studies. This situation makes it impossible to develop a construct of radicalisation that could be operationalised for diagnosing the risk of religious radicalisation of Russian youth.&#x0D; The purpose of the research is to verify the theoretical model (construct) of religious radicalisation, as well as to develop a questionnaire based on it, which makes it possible to measure the risk of religious radicalisation of young people through the study of attitudes towards religion and believers.&#x0D; It is supposed that religious radicalisation is formed under the influence of the social environment on the subject’s perceptions of the importance of religion and believers for society and the state. Based on the analysis of theoretical knowledge about radicalisation, facts and information about the activities of destructive religious and extremist communities, a model of religious radicalisation is proposed, including six statements: about the exclusive importance of religion, religious leaders and believers (sacralisation and clericalisation), the need to protect them from changes, interference of non-believers or representatives of another religion (fundamentalism and xenophobia), to maintain relations only with representatives of a particular religious association, including in matters of education, cultural and social development, ignoring or failing to comply with obligations, laws and regulations (socialisation and discrimination).&#x0D; Methodology, methods and techniques. The methodological basis of the research is the socio-psychological approach in the study of human cognition of society (G.M. Andreeva), empirical concepts of religious radicalisation of individuals and groups (A.W. Kruglanski, N. Ellemers, A. R. Schmidt, etc.).&#x0D; The empirical research is aimed at testing the theoretical model of religious radicalisation; development and verification of a questionnaire to study the risk of religious radicalisation.&#x0D; The method of data collection is the questionnaire «Religious radicalisation», structurally corresponding to the theoretical model of radicalisation, including 90 questions grouped into six scales, as well as indicators of religious self-determination and religious behavior.&#x0D; Results processing method: descriptive statistics, correlation, one-factor analysis of variance and confirmatory analysis.&#x0D; Research sample: 874 people divided into Russian (n=336 people), Kyrgyz (268 people) and Uzbek (n=270 people) sub-samples of young people.&#x0D; Results: by means of confirmatory factor analysis of the results of the survey of national samples, the theoretical model of youth radicalisation was corrected. A three-factor empirical model was found to have the best structural characteristics for the Russian sample (χ2=216.5, df=87, p&lt;0.0001, RMSEA=0.067, p=0.008 (RMSEA CI 90% = 0.056-0.078), CFI=0.949, TLI=0.95). The model consists of three scales from the theoretical model (‘Clericalisation’, ‘Discrimination’, ‘Xenophobia’) but includes statements from other scales from the theoretical model (‘Sacralisation’, ‘Fundamentalism’, ‘Socialisation’).&#x0D; The second result was the verification of a questionnaire to study the risk of religious radicalisation among Russian youth. The questionnaire consists of 15 statements, grouped into three scales, has satisfactory reliability values according to the internal consistency criterion and intercorrelations (Cronbach’s α «Clericalisation» = 0.89, r=0.63, p&lt;0.001; «Discrimination» = 0.76, r=0.38, p&lt;0.001; Xenophobia = 0.81, r=0.46, p&lt;0.001).&#x0D; Scientific novelty. The received results expand the idea of socio-psychological preconditions of religious radicalisation, demonstrate a set of beliefs that can stimulate intolerant attitude of young people to religion and believers.&#x0D; Practical significance. The presented methodology can be used for research purposes to study the preconditions of religious radicalisation of young people.

PECULIARITIES OF THE BEHAVIOR OF BULLS-CALFS OF UKRAINIAN GRAY BREED AND ITS RELATIONSHIP WITH LIVE WEIGHT GAINS

PECULIARITIES OF THE BEHAVIOR OF BULLS-CALFS OF UKRAINIAN GRAY BREED AND ITS RELATIONSHIP WITH LIVE WEIGHT GAINS

MILK PRODUCTIVITY AND REPRODUCTIVE CAPACITY OF COWS DEPENDS ON DIFFERENT MILK PRODUCTION TECHNOLOGIES

MILK PRODUCTIVITY AND REPRODUCTIVE CAPACITY OF COWS DEPENDS ON DIFFERENT MILK PRODUCTION TECHNOLOGIES

The Formation of the Core of the Hirsch Index of the Pedagogical Universities of Ukraine: The Gender Features

In the article, the authors disclosed the results of the study that was conducted with the aim of determining the gender characteristics of the groups of the authors of articles that were included in the core of the Hirsch index for each pedagogical university of Ukraine (according to the SciVerse Scopus database) as well as to analyze the influencing factors on the formation of the core of the Hirsch index of these universities in the context of the gender division. For this purpose, one-factor variance analysis and elementary methods of statistical analysis were used - a calculation of percentage ratios and determination of gender asymmetry indices. The gender analysis of the group of authors whose articles were included in the h-index core of each university showed that in the presence of the general gender parity in the gender groups of authors whose articles are indexed by the Scopus database, there is a gender asymmetry between the gender groups of authors of articles from the core in favor of the male authors. The same tendency occurs between the gender groups of authors, whose articles were included in the core of the h-index of the combined list of all the pedagogical universities of Ukraine: both for the ratio of the groups of authors of articles, and for the ratio of contributions of the groups to the core. As a result of a series of univariate variance analyzes of the influence of the external factors on the formation of the Hirsch index core, a significant gender difference was revealed when analyzing the following factors: presence/absence of publication funding (articles that have funding have a much higher citation rate), publication quartile (articles placed in publications of the first quartile, are cited much more often) and the age of the article (the older the article, the higher its citation index). At the same time, factors such as the number of authors of the article and the type of access to the article did not influence the formation of the core of the h-index of the pedagogical higher educational institutions. Moreover, only one factor (the availability of access to the article) can be characterized as a gender parity. On the contrary, there is an obvious gender difference in the distribution of the number of authors in the articles, the availability of funding for the publication, the “age” of the article, and in the distribution of articles by the publications of the first two quartiles.

FACTORS OF CUSTOMER SATISFACTION WITH THE QUALITY OF BANKING SERVICES AND PREDICTION OF THEIR SIGNIFICANCE

In modern business, the quality of products and services is, not without reason, given considerable attention. That is why it is understandable that quality is considered a key business paradigm in banking as well. In particular, the quality of banking services is viewed as an essential prerequisite for gaining new clients and retaining existing ones. In this paper, scientific attention is focused on researching the factors of customer satisfaction with the quality of banking services and predicting their importance. In line with that, a descriptive "survey" method (survey-research method) was applied, while other methods were not completely ignored, because without of them a complete answer to all the questions could not be given. By applying factor analysis (orthogonal varimax method), five factors were obtained, which were, in further data processing and analyzing the research results, treated as the main factors of client satisfaction with the quality of banking services. One-factor analysis of variance - ANOVA - was used to predict the importance of selected factors from the client's point of view. The results of this research can contribute to the improvement of customer relations by improving the existing practice of managing customer relations.&#x0D; &#x0D;

Adult education and training for the development of problem-solving skills

Introduction. Currently, the presence of employees with developed basic skills of working with textual and numerical information can no longer explain how effectively a person functions in society and the professional sphere. This is due to the rapid transformation of the innovative economy and the renewal of production technologies and business processes. Therefore, the key basic skills of the adult population have been supplemented with one more cognitive skill – problem solving. Aim. The present research aimed to present a portrait of a person with a developed problem-solving skill on the basis of sociological data, and to identify which types of employee training could most effectively lead to his/her development during participation in educational activities. Materials and methods. The study was based on theoretical methods of literature analysis, which made it possible to describe the categorical field and to systematize existing scientific approaches. The empirical foundation for this research was built on the data of OECD-PIAAC studies in Russia (2013). The study sample consisted of 3,877 people employed in various sectors of economic activity. To process the results obtained, the authors used the methods of mathematical statistics (descriptive statistics, one-factor analysis of variance, regression analysis method). Results. It was discovered that even prolonged employer-provided training does not lead to development of problem-solving skills, but still provides an increase in salary for some workers. Moreover, training which is not directly connected to the professional field and not initiated by the employer would lead to increase in problem-solving skills in a technology-rich environment. In this study, it is debated that the most significant increase in problem solving skills was brought by informal on-the-job training. It was shown that problem-solving skills provide significant increase in labour productivity in the production fields and intellectual labour fields (education and science). At the same time, problem-solving skills barely provide any increase in labour productivity in the routine fields, because such type of jobs does not involve behavioural variability, operational problem solving, and constant cooperation with other people. Scientific novelty. For the first time in the Russian academic literature, the authors conceptualised the concept of problem-solving skills and clarified which types of training significantly increase the contribution to the development of human capital of Russian workers. Based on the results of the study the authors presented a sociological portrait of a Russian worker with a high and low level of problem-solving skills. The revealed patterns allowed the authors to form an idea of the system of organisational conditions of enterprises that ensure maximum involvement of employees in the constant updating of their knowledge and skills, and contribute to the effective use of the problems-solving skill in the process of labour activity. Practical significance. This article might be of interest for the specialists in sphere of adult education and lifelong learning, HR-specialists and small and medium-sized enterprise managers in order to improve the efficiency of the recruitment process and to adopt more efficient employer-provided training systems.

Transformation of the Education System in Agricultural Advisory towards Sustainability—A Case Study in Slovenia

The new role that agricultural advisory plays in innovation processes and the development of agriculture towards sustainability requires the improvement of its performance. The basic prerequisite for realizing the potential of agricultural advisory in the areas mentioned is a strongly developed education system that will enable the development of strong advisory capacities. This survey is based on three areas of the education system: organization of education, satisfaction with educators, and evaluation of education and the potential of individuals in the organization. The basic principles on which the education system is based are outdated and, therefore, inadequate for developing the performance that the new role of agricultural advisors in innovation processes requires. Multiple regression analysis results indicate that a greater evaluation of education and the potential of individuals in the organization implies greater involvement of agricultural advisors in the selection of topics that will be provided to them through education and more advanced performances of educators responsible for educating. One-factor analysis of variance (ANOVA) determined that there are no statistically significant differences, at the p &lt; 0.05 level, in the level of perceived competence of advisors for sustainable agricultural practices depending on the frequency of attending education.

Differences between girls and boys based on basic psychomotor skills

According to the aim of the research and the set hypotheses, the scientific methodology was consistently implemented with the application of adequate classical and neoclassical statistical methods and tests. Following the set hypotheses, the following conclusions can be drawn. The first hypothesis H1 assumes that boys will have better results than girls at the beginning of the school year (first measurement) and that these differences will be statistically significant at the Sig.≤.05 error level. One-factor analysis of variance "Anova" shows that there is a statistically significant difference between boys and girls in favor of boys (Chi-square=29.36, df=8, Sig.&lt;.00). Statistically significant correlation with the discriminative function had variables: (SHR, BAH, SBJ and SAR). Tables 1&amp;2. Differences between girls and boys were not established for the variables: (FTR, PLT, SUP and HIG). That there is a difference at the general level is confirmed by the centroid distance. In accordance with according to the results in Tables 3–6 as well as Graphs 1&amp;2, hypothesis H1 remains valid, the probability of statistical error is less than 1%. The second hypothesis H2 assumes that even at the end of the school year (second measurement) boys will also have better results than their female peers, as well as that the difference will be statistically significant. Comparing the arithmetic means (Tables 1&amp;2), it is evident that in the second measurement the results were better, as if on average the girls were slightly higher. Table 7 shows the results of the one-factor analysis of variance "Anova" and the statistical significance of the differences for each test, including body height. Values in Table 7 column Sig. shows and shows that there is no statistically significant difference between girls and boys in any test. There is a difference between the arithmetic means, but these differences are not large enough to be statistically significant. Discriminative coefficients: Eigen value .071, Shi-sque 6.16, centroid distance (.242:-.286) and finally Sig.=.63 confirm that the differences are not statistically significant. Considering the results of the research, hypothesis H2 can be rejected, noting that girls have improved more.

Psychological Analysis of Manifestations of Nonverbal Intelligence of Senior Pre-Schoolers in the Context of Inclusive Education

Inclusive preschool education ensures the full development of pre-schoolers with disabilities and promotes their social adaptation. The use of visual material is one of the effective means of stimulating cognitive activity in the process of preschool inclusion. The success of its perception and assimilation depends on the level of non-verbal intelligence.&#x0D; Aim: The research aims to analyze the manifestations of non-verbal intelligence in healthy senior pre-schoolers and children with disabilities.&#x0D; Methods: The research involved theoretical methods of systematization and generalization of academic information, as well as empirical methods of psychological diagnostics. Statistical indicators were determined through descriptive statistics and a one-factor analysis of variance.&#x0D; Results: The study's results showed a high level of nonverbal intelligence and creative abilities in healthy senior pre-schoolers and pre-schoolers with disabilities. The analysis didn’t reveal any statistically significant differences (р≥0.05) between the indicators of non-verbal intelligence of the studied healthy senior pre-schoolers and pre-schoolers with disabilities.&#x0D; Conclusions: children with disabilities have medium-high indicators of the development of non-verbal intelligence and creative abilities, which do not statistically differ from the indicators of their healthy peers.&#x0D; Prospects: The obtained results can contribute to developing adaptation schemes for children with disabilities in the context of inclusive education. The obtained data provide the background for expanding the teaching materials for developing non-verbal intelligence in inclusive groups.

Evaluation of Leukocytes, B and T Lymphocytes, and expression ofCD200 and CD23on B lymphocytes in Patients with Atopic Dermatitis on Dupilumab Therapy-Pilot Study.

There are a lot of studies that describe the change in quantity of T cells in patients with atopic dermatitis (AD) compared with healthy subjects. Other components of lymphocytes such as B cells are not examined as well as T cells. We focus on immunophenotyping of B cells with their subsets (memory, naïve, switched, non-switched) and the expression of CD23 and CD200 markers in patients with AD with and without dupilumab therapy. We also evaluate the count of leukocytes and their subsets, Tlymphocytes (CD4+, CD8+), natural killer (NK) cells, and Tregulatory cells. A total of 45 patients suffering from AD were examined: 32 patients without dupilumab treatment (10 men, 22 women, average age 35years), 13 patients with dupilumab treatment (7 men, 6 women, average age 43.4years), and 30 subjects as a control group (10 men, 20 women, average age 44.7years). Immunophenotype was examined by flow cytometry in which monoclonal antibodies with fluorescent molecules were used. We compared the absolute and relative count of leukocytes and their subsets, T lymphocytes (CD4+ , CD8+), NK cells, Tregulatory cells, absolute and relative count of B lymphocytes (memory, naïve, non-switched, switched, transient), and expression of CD23 and CD200 activation markers on B cells and on their subsets in patients with AD and control group. For statistical analysis we used nonparametric Kruskal-Wallis one-factor analysis of variance with posthoc by Dunn's test with Bonferroni modification of significance level. In patients with AD with and without dupilumab therapy we confirmed the significantly higher count of neutrophils, monocytes, and eosinophils; there was no difference in absolute count of B cells, NK cells and transitional B cells compared with control subjects. We confirmed higher expression of activation marker CD23 on total, memory, naïve, non-switched, and switched Blymphocytes and higher expression of CD200 on total Blymphocytes in both groups of patients with AD compared with controls. In patients without dupilumab therapy we confirmed significantly higher count of relative monocytes, relative eosinophils, and higher expression of CD200 on memory, naïve, and non-switched Blymphocytes compared with controls. In patients with dupilumab therapy we confirmed significantly higher expression of CD200 on switched B lymphocytes, higher count of relative CD4+ Tlymphocytes, and lower count of absolute CD8+ T lymphocytes compared with controls. This pilot study shows higher expression of CD23 on B lymphocytes and on their subsets in patients with AD with and without dupilumab therapy. The higher expression of CD200 on switched B lymphocytes is confirmed only in patients with AD with dupilumab therapy.