B-spline box-based multi-channel calculations of transition probabilities in noble gases are reported for energy levels up to n= 12. Energy levels and oscillator strengths for transitions from the p6 ground-state configuration, as well as for transitions between excited states, have been computed in the Breit–Pauli approximation. Individually optimized, term-dependent sets of non-orthogonal valence orbitals are used to account for the strong term dependence in the one-electron orbitals. The agreement in the length and velocity gauges of the transition data and the accuracy of the binding energies are used to estimate the accuracy of our results, which are also compared with experimental and other theoretical data. It is shown that the present method can be used for accurate calculations of oscillator strengths for states with intermediate to high n-values, for which it is difficult to apply standard multi-configuration Hartree–Fock (MCHF) methods. Recent developments based on the extension of our computer codes from the semi-relativistic Breit–Pauli Hamiltonian to the full relativistic Dirac–Breit Hamiltonian are also reported.