Purpose The purpose of this study is to present a multi-scale analysis methodology for calculating the effective stiffnesses and the micro stresses of helically wound structures efficiently and accurately. The helically wound structure is widely applied in ocean and civil engineering as load-bearing structures with high flexibility, such as wire ropes, umbilical cables and flexible risers. Their structures are usually composed of a number of twisted subcomponents with relatively large slender ratio and have the one-dimensional periodic characteristic in the axial direction. As the huge difference between the axial length and the cross-section size of this type of structures, the finite element modeling and theoretical analysis based on some assumption are usually unavailable leading to the reduction of computability; even the optimization design becomes infeasible. Design/methodology/approach Based on the asymptotic homogenization theory, the one-dimensional periodic helically wound structure is equivalent to the one-dimensional homogeneous beam. A novel implementation of the homogenization is derived for the analysis of the effective mechanical properties of the helically wound structure, and the tensile, bending, torsional and coupling stiffness properties of the effective beam model are obtained. On this basis, a downscaling analysis formation for the micro-component stress in the one-dimensional periodic wound structure is constructed. The stress of micro-components in the specified geometry position of the helically wound structure is obtained basing on the asymptotic homogenization theory simultaneously. Findings By comparing with the result from finite element established accurately, the established multi-scale calculation method of the one-dimensional periodic helically wound structure is verified. The influence of size effects on the macro effective performance and the micro-component stress is discussed. Originality/value This paper will provide the theoretical basis for the efficient elastoplastic analysis of the helically wound structure, even the fatigue analysis. In addition, it is necessary to point out that the axial length of the helically wound structure in the general engineering problems that such as deep-sea risers and submarine cables.