ISOLDE Research Articles

In situ diffusion measurements in solids using short-lived radioactive tracers of [formula omitted] and [formula omitted

We are developing in situ diffusion measurements in solids using short-lived radioactive ion beams provided from an isotope separator on-line (ISOL). We examined the feasibility of a new in situ nanoscale diffusion measurement method using a radioactive 8Li tracer by computer simulations. Under moderate experimental conditions, we have found that the detection limit of lithium diffusion coefficient can be improved to a low value of 1×10-12cm2/s. Also, in situ sodium diffusion measurement in Na battery materials can be applicable using a radioactive 20Na tracer. We found Na diffusion coefficients can be measured, ranging from 10-6 to 10-10cm2/s by computer simulations.

A test-bench for isotope separator on-line of Beijing radioactive ion-beam facility

A test-bench for isotope separator on-line of Beijing radioactive ion-beam facility (BRISOL) has been built in China Institute of Atomic Energy (CIAE). The test-bench consists of target station, charge exchange cell, mass separator, quadrupole, hexapole, multipole and beam diagnostic system. It is nearly the same configuration as the first stage of BRISOL and all these components will be used on the BRISOL. A series of experiments have been carried out on this test-bench, and the primary results showed that all the components worked well. A Li+ beam has been generated from the positive surface-ionization source and its emittance and the transmission of the beam line have been measured. The design, construction and experimental results of this test-bench have been presented.

Development of target ion source systems for radioactive beams at GANIL

The GANIL facility (Caen, France) is dedicated to the acceleration of heavy ion beams including radioactive beams produced by the Isotope Separation On-Line (ISOL) method at the SPIRAL1 facility. To extend the range of radioactive ion beams available at GANIL, using the ISOL method two projects are underway: SPIRAL1 upgrade and the construction of SPIRAL2. For SPIRAL1, a new target ion source system (TISS) using the VADIS FEBIAD ion source coupled to the SPIRAL1 carbon target will be tested on-line by the end of 2013 and installed in the cave of SPIRAL1 for operation in 2015. The SPIRAL2 project is under construction and is being design for using different production methods as fission, fusion or spallation reactions to cover a large area of the chart of nuclei. It will produce among others neutron rich beams obtained by the fission of uranium induced by fast neutrons. The production target made from uranium carbide and heated at 2000°C will be associated with several types of ion sources. Developments currently in progress at GANIL for each of these projects are presented.

Recent developments of target and ion sources to produce ISOL beams

In this review on target and ion sources for ISOL (Isotope Separation OnLine) beams, important developments from the past five years are highlighted. While at precedent EMIS conferences, a particular focus was given to a single topics, for instance specifically on ion sources or on chemical purification techniques, here each of the important elements present in an ISOL production unit is discussed. Fast diffusing nanomaterials, uranium-based targets, high power targets for next generation facilities, purification by selective adsorption, new ion sources are all part of this review. For each of these selected topics, the reported results lead to significant gains in intensity, purity, or quality of the delivered beam, or in the production of new isotope beams. Often the outcome resulted from the combination of original ideas with state-of-the-art investigations; this was carried out using very different scientific disciplines, leading to understanding of the underlying chemical or physical mechanisms at the origin of the improvements.

An overview of the HIE-ISOLDE Design Study

The On-Line Isotope Mass Separator ISOLDE [1] is a facility dedicated to the production of a large variety of radioactive ion beams (RIB) for a great number of different experiments. Over 1000 radioactive nuclides from 70 elements can be produced in thick high-temperature targets via spallation, fission or fragmentation reactions with the PS-Booster pulsed proton-beam. With the arrival of CERN’s new linear accelerator Linac 4 [2,3], ISOLDE will have the possibility to exploit a factor of 3 increase in proton-beam intensity and a possible proton-beam energy increase from 1.4GeV to 2GeV [4].After 20years of successful ISOLDE operation at the PS-Booster, a major upgrade of the facility, the HIE-ISOLDE (High Intensity and Energy ISOLDE) project was launched in 2010. It is divided into three parts; a staged upgrade of the REX post-accelerator to increase the beam energy from 3.3MeV/u to 10MeV/u using a super-conducting Linac, an evaluation of the critical issues associated with an increase in proton-beam intensity and a machine design for an improvement in RIB quality. The latter two will be addressed within the HIE-ISOLDE Design Study. This paper gives an overview of the Design Study and will outline the critical issues to be addressed concerning the intensity upgrade and will propose solutions and improvements to be implemented. It will also give an insight to the propositions being studied in order to improve secondary beam characteristics essential to accomplish a more demanding physics program.

Towards commissioning the new IGISOL-4 facility

The Ion Guide Isotope Separator On-Line facility at the Accelerator Laboratory of the University of Jyväskylä is currently being re-commissioned as IGISOL-4 in a new experimental hall. Access to intense beams of protons and deuterons from a new MCC30/15 cyclotron, with continued possibility to deliver heavy-ion beams from the K=130MeV cyclotron, offers extensive opportunities for long periods of fundamental experimental research, developments and applications. A new layout of beam lines with a considerable increase in floor space offers new modes of operation at the facility, as well as a possibility to incorporate more complex detector setups. We present a general overview of IGISOL-4 and the current status of several projects, including the collinear laser spectroscopy station and the future of neutron-induced fission. Recent milestones from the first commissioning experiments are presented.

Experimental systems overview of the Rare Isotope Science Project in Korea

The Rare Isotope Science Project (RISP) was launched by the Institute for Basic Science (IBS) in December 2011 in Korea. The project aims to construct the new accelerator complex consisting of the Isotope Separation On-Line (ISOL) and the In-Flight Fragment (IF) facilities for the rare isotope science. The scientific programs and the experimental systems of RISP are briefly introduced with an overview of the complex.

Rare isotope accelerator project in Korea and its application to high energy density sciences

As a national science project, the Korean government has recently established the Institute for Basic Science (IBS) with the goal of conducting world-class research in basic sciences. One of the core facilities for the IBS will be the rare isotope accelerator which can produce high-intensity rare isotope beams to investigate the fundamental properties of nature, and also to support a broad research program in material sciences, medical and biosciences, and future nuclear energy technologies. The construction of the accelerator is scheduled to be completed by approximately 2017. The design of the accelerator complex is optimized to deliver high average beam current on targets, and to maximize the production of rare isotope beams through the simultaneous use of Isotope Separation On-Line (ISOL) and In-Flight Fragmentation (IFF) methods. The proposed accelerator is, however, not optimal for high energy density science, which usually requires very high peak currents on the target. In this study, we present possible beam–plasma experiments that can be done within the scope of the current accelerator design, and we also investigate possible future extension paths that may enable high energy density science with intense pulsed heavy ion beams.

An IGISOL portrait

This issue of Hyperfine Interactions consists of 21 articles describing scientific work related to the research at the on-line isotope separator facility IGISOL at the University of Jyvaskyla, Finland. Ten contributions containing a significant amount of original results, earlier unpublished, have been presented as a Topical Collection in the European Physical Journal (EPJA 48 issue No 4, 2012). In the early 1980s, the Ion Guide Isotope Separator On-Line (IGISOL) concept was realized at the 20 MeV proton cyclotron of the Physics Department at the University of Jyvaskyla (JYFL). For the first time, the technique allowed the production of high quality ISOL beams from nuclear reaction products with millisecond delay times without chemical restrictions. By providing access to short-lived isotopes of refractory elements it opened up new regions in the nuclear chart for nuclear decayand ground-state spectroscopy. During the 1980s, the main research activity at IGISOL was decay spectroscopy, and in particular, of fission products produced in proton-induced fission of natural uranium. Approximately 40 new isotopes and isomers were discovered and studied employing beta-, gamma-, and conversion electron spectroscopy. These experiments covered a broad range of neutron-rich nuclei from yttrium (Z = 39) to cadmium (Z = 48) and revealed how their structure was developing between highly deformed zirconium through triaxial ruthenium isotopes to weakly deformed vibrational cadmium isotopes. The original IGISOL facility was shut down in October 1991 and was reinstalled as IGISOL-2 at the science campus housing the laboratory for the K = 130 MeV heavy ion cyclotron. A new window of opportunity for extending research to neutrondeficient nuclei far from stability was opened and was going to have a strong impact

The IGISOL technique—three decades of developments

The Ion Guide Isotope Separator On-Line (IGISOL) technique, conceived in the early 1980s as a novel variation to the helium-jet method, has been used to provide radioactive ion beams of short-lived exotic nuclei for fundamental nuclear structure research and applications for three decades. This direct on-line mass separation of primary recoil ions from nuclear reactions has achieved similar extraction efficiencies for both volatile and non-volatile elements throughout the periodic table. The evolution of the ion guide has been driven by the pursuit of physics research on both sides of the valley of beta stability. The gradual improvement in the primary beam intensities of light ions, as well as the ever increasing availability of a range of heavy ions has been matched with the development of novel ion manipulation techniques in order to maximise the output of the IGISOL facility. In this article we describe the continual development of the facility to match the needs of the scientific programme, a relationship which has proceeded hand-in-hand over the years. We will show that this strategy has been and continues to be very important for the huge success of the ion guide method for radioactive ion beam production.

Neutron-rich isotope production using a uranium carbide - carbon nanotubes SPES target prototype

The SPES (Selective Production of Exotic Species) project, under development at the Istituto Nazionale di Fisica Nucleare - Laboratori Nazionali di Legnaro (INFN-LNL), is a new-generation Isotope Separation On-Line (ISOL) facility for the production of radioactive ion beams by means of the proton-induced fission of uranium. In the framework of the research on the SPES target, seven uranium carbide discs, obtained by reacting uranium oxide with graphite and carbon nanotubes, were irradiated with protons at the Holifield Radioactive Ion Beam Facility (HRIBF) of Oak Ridge National Laboratory (ORNL). In the following, the yields of several fission products obtained during the experiment are presented and discussed. The experimental results are then compared to those obtained using a standard uranium carbide target. The reported data highlights the capability of the new type of SPES target to produce and release isotopes of interest for the nuclear physics community.

Production of 62Zn radioactive nuclear beam and on-line PAC investigation of quadrupole interaction in nano-magnetic material Fe73.5Cu1Nb3Si13.5B9

An Isotope Separator On-Line (ISOL), dedicated to on-line perturbed angular correlation (PAC) and positron annihilation spectroscopy (PAS), has been constructed at CIAE based on the HI-13 tandem accelerator, and a 30 keV radioactive beam of 62Zn with intensity of 2 ×107/s produced by it. Using the 62Zn radioactive beam the investigation of the nano-crystalline soft magnetic Fe73.5Cu1Nb3Si13.5B9 materials has been fulfiled for the first time by the on-line time differential PAC technique. Two quadrupole interaction frequencies ω01 ( = 440 Mrad/s) and ω02 ( = 90 Mrad/s) were gained, indicating there are two implantation sites of 62Zn. The frequency ω02 shows a fluctuation of the crystal lattice constants and proves the characteristic distribution model of nano-crystalline grain boundary. The frequency ω01 demonstrates that the implanted 62Zn occupies the site of the ordered grain core. The fractions of ω01 and ω02 are f01 = 38 % and f02 = 62 %, respectively.

In-source laser spectroscopy developments at TRILIS—towards spectroscopy on actinium and scandium

Resonance Ionization Laser Ion Sources (RILIS) have become a versatile tool for production and study of exotic nuclides at Isotope SeparatorOn-Line (ISOL) facilities such as ISAC at TRIUMF. The recent development and addition of a grating tuned spectroscopy laser to the TRIUMF RILIS solid state laser system allows for wide range spectral scans to investigate atomic structures on short lived isotopes, e.g., those from the element actinium, produced in uranium targets at ISAC. In addition, development of new and improved laser ionization schemes for rare isotope production at ISAC is ongoing. Here spectroscopic studies on bound states, Rydberg states and autoionizing (AI) resonances on scandium using the existing offline capabilities are reported. These results allowed to identify a suitable ionization scheme for scandium via excitation into an autoionizing state at 58,104 cm−1 which has subsequently been used for ionization of on-line produced exotic scandium isotopes.

The Miniball spectrometer

The Miniball germanium detector array has been operational at the REX (Radioactive ion beam EXperiment) post accelerator at the Isotope Separator On-Line facility ISOLDE at CERN since 2001. During the last decade, a series of successful Coulomb excitation and transfer reaction studies have been performed with this array, utilizing the unique and high-quality radioactive ion beams which are available at ISOLDE. In this article, an overview is given of the technical details of the full Miniball setup, including a description of the \(\gamma\)-ray and particle detectors, beam monitoring devices and methods to deal with beam contamination. The specific timing properties of the REX-ISOLDE facility are highlighted to indicate the sensitivity that can be achieved with the full Miniball setup. The article is finalized with a summary of some physics highlights at REX-ISOLDE and the utilization of the Miniball germanium detectors at other facilities.

First on-line results from the CRIS (Collinear Resonant Ionisation Spectroscopy) beam line at ISOLDE

The CRIS (Collinear Resonant Ionisation Spectroscopy) experiment at the on-line isotope separator facility, ISOLDE, CERN, has been constructed for high-sensitivity laser spectroscopy measurements on radioactive isotopes. The technique determines the magnetic dipole and electric quadrupole moments, nuclear spin and changes in mean-square charge radii of exotic nuclei via measurement of their hyperfine structures and isotope shifts. In November 2011 the first on-line run was performed using the CRIS beam line, when the hyperfine structure of 207Fr was successfully measured. This paper will describe the technique and experimental setup of CRIS and present the results from the first on-line experiment.

First successful ionization of Lr (Z = 103) by a surface-ionization technique

We have developed a surface ionization ion-source as part of the JAEA-ISOL (Isotope Separator On-Line) setup, which is coupled to a He/CdI2 gas-jet transport system to determine the first ionization potential of the heaviest actinide lawrencium (Lr, Z = 103). The new ion-source is an improved version of the previous source that provided good ionization efficiencies for lanthanides. An additional filament was newly installed to give better control over its operation. We report, here, on the development of the new gas-jet coupled surface ion-source and on the first successful ionization and mass separation of 27-s (256)Lr produced in the (249)Cf + (11)B reaction.

A test stand for off-line laser ion source development at TRIUMF

A test stand for ion source development and laser resonance ionization spectroscopy was built and commissioned at TRIUMF. The test stand is needed to develop efficient ion sources that can function reliably in the hostile, high temperature, high radiation environment of TRIUMF's isotope separator on-line (ISOL) production target ion source. In addition, it enables laser resonance ionization spectroscopy to develop laser excitation schemes suitable for the solid-state laser systems used with TRIUMF's resonant ionization laser ion source . Also, it allows for possible improvement of current ion sources and validation of new designs. The test stand employs a copy of the ion optics used on-line, so that results can be transferred directly to radioactive ion beam production. Due to space restrictions and the need for rapid mass scans, a quadrupole mass spectrometer is used as a mass separator. One of the first experiments conducted on the laser ion source test stand (LIS STAND) was resonant ionization spectroscopy of gallium to improve on the ionization scheme previously used on-line, so that low yield isotopes (e.g., (62)Ga) become available for experiments. Different Rydberg series in gallium were observed and autoionizing states were searched for. The overall LIS STAND system performance, characteristics, and the first resonant ionization spectroscopy are described.

A Unique Matched Quadruplet of Terbium Radioisotopes for PET and SPECT and for α- and β−-Radionuclide Therapy: An In Vivo Proof-of-Concept Study with a New Receptor-Targeted Folate Derivative

Terbium offers 4 clinically interesting radioisotopes with complementary physical decay characteristics: (149)Tb, (152)Tb, (155)Tb, and (161)Tb. The identical chemical characteristics of these radioisotopes allow the preparation of radiopharmaceuticals with identical pharmacokinetics useful for PET ((152)Tb) and SPECT diagnosis ((155)Tb) and for α- ((149)Tb) and β(-)-particle ((161)Tb) therapy. The goal of this proof-of-concept study was to produce all 4 terbium radioisotopes and assess their diagnostic and therapeutic features in vivo when labeled with a folate-based targeting agent. (161)Tb was produced by irradiation of (160)Gd targets with neutrons at Paul Scherrer Institute or Institut Laue-Langevin. After neutron capture, the short-lived (161)Gd decays to (161)Tb. (149)Tb, (152)Tb, and (155)Tb were produced by proton-induced spallation of tantalum targets, followed by an online isotope separation process at ISOLDE/CERN. The isotopes were purified by means of cation exchange chromatography. For the in vivo studies, we used the DOTA-folate conjugate cm09, which binds to folate receptor (FR)-positive KB tumor cells. Therapy experiments with (149)Tb-cm09 and (161)Tb-cm09 were performed in KB tumor-bearing nude mice. Diagnostic PET/CT ((152)Tb-cm09) and SPECT/CT ((155)Tb-cm09 and (161)Tb-cm09) studies were performed in the same tumor mouse model. Carrier-free terbium radioisotopes were obtained after purification, with activities ranging from approximately 6 MBq (for (149)Tb) to approximately 15 MBq (for (161)Tb). The radiolabeling of cm09 was achieved in a greater than 96% radiochemical yield for all terbium radioisotopes. Biodistribution studies showed high and specific uptake in FR-positive tumor xenografts (23.8% ± 2.5% at 4 h after injection, 22.0% ± 4.4% at 24 h after injection, and 18.4% ± 1.8% at 48 h after injection). Excellent tumor-to-background ratios at 24 h after injection (tumor to blood, ≈ 15; tumor to liver, ≈ 5.9; and tumor to kidney, ≈ 0.8) allowed the visualization of tumors in mice using PET ((152)Tb-cm09) and SPECT ((155)Tb-cm09 and (161)Tb-cm09). Compared with no therapy, α- ((149)Tb-cm09) and β(-)-particle therapy ((161)Tb-cm09) resulted in a marked delay in tumor growth or even complete remission (33% for (149)Tb-cm09 and 80% for (161)Tb-cm09) and a significantly increased survival. For the first time, to our knowledge, 4 terbium radionuclides have been tested in parallel with tumor-bearing mice using an FR targeting agent. Along with excellent tumor visualization enabled by (152)Tb PET and (155)Tb SPECT, we demonstrated the therapeutic efficacy of the α-emitter (149)Tb and β(-)-emitter (161)Tb.

Optimization studies of the CERN-ISOLDE neutron converter and fission target system

The ISOLDE facility at CERN has been one of the leading isotope separator on-line (ISOL) facilities worldwide since it became operative in 1967. More than 1000 isotopes are available at ISOLDE, produced after the bombardment of various primary targets with a pulsed proton beam of energy 1.4 GeV and an average intensity of 2 μA. A tungsten solid neutron converter has been used for ten years to produce neutron-rich fission fragments in UCx targets. In this work, the Monte Carlo code FLUKA and the cross-section codes TALYS and ABRABLA were used to study the current layout of the neutron converter and fission target system of the ISOLDE facility. An optimized target system layout is proposed, which maximizes the production of neutron-rich isotopes and reduces the contamination by undesired neutron-deficient isobars. The studies here reported can already be applied to ISOLDE and will be of special relevance for the future facilities HIE-ISOLDE and EURISOL.

Overview of the KoRIA Facility for Rare Isotope Beams

The Korea Rare Isotope Accelerator, currently referred to as KoRIA, is briefly presented. The KoRIA facility is aimed to enable cutting-edge sciences in a wide range of fields. It consists of a 70 kW isotope separator on-line (ISOL) facility driven by a 70 MeV, 1 mA proton cyclotron and a 400 kW in-flight fragmentation (IFF) facility. The ISOL facility uses a superconducting (SC) linac for post-acceleration of rare isotopes up to about 18 MeV/u, while the SC linac of IFF facility is capable of accelerating uranium beams up to 200 MeV/u, 8 pμA and proton beams up to 600 MeV, 660 μA. Overall features of the KoRIA facility are presented with a focus on the accelerator design.