Ongoing Abuse Research Articles

The Efficacy of Quinolones and Fluoroquinolones in the Medicine: a review study

Background: Previous studies have shown that several antibiotics have significant side effects in addition to their antibacterial ones, which are indirectly mediated by altering and controlling the mediators of the immune system. The synthetic antibiotics known as fluoroquinolones (FQs) were discovered that fluoroquinolones (FQs) have an impact on humoral and cellular immunity. Typically, FQs only have their moderating effects when combined with another stimulant. Conclusion: This review presented the suitability of fluoroquinolones for potential use in medicine in order to manage several infectious diseases. These FQs are highly effective antibiotics against the bacterial infections. They are therefore prone to misuse, which can result in patients experiencing unwanted side effects and the continued development of antibiotic resistance. Even though quinolones can be used empirically to treat patients in an outpatient setting, doctors still need to follow up with patients to make sure the course of antibiotics is completed and to confirm the success of the treatment. When culture and sensitivity data are available, patients should be switched to more focused antibiotics so that quinolones can be stopped. It is advisable for clinicians to use another antibiotic if a patient is at high risk for serious side effects. In order to discuss alternate antibiotics, confirm dosage, and find any drug-drug interactions, a pharmaceutical consultation may be beneficial. In order to prevent serious side effects from occurring when using quinolones, the patient and their healthcare providers should be informed by the pharmacist and the doctor. Physicians should exercise caution while treating life-threatening gram-positive infections with quinolone antibiotics, even if the more recent fluoroquinolones have demonstrated encouraging in vitro activity against gram-positive bacteria based on MIC data. Future quinolone efficacy is likely to be constrained by the ongoing abuse of these antibiotics in clinical care and agricultural feed, which will encourage gram-positive and gram-negative resistance. Overuse of one agent will eventually cause the class as a whole to become resistant.

"Holding the badness": Therapists' experiences of treating incestuous abuse continuing into adulthood.

This study aimed to explore the experience of therapists whose clients report incestuous abuse continuing into adulthood. Ten Australian therapist-participants were recruited through professional forums. After giving informed consent, they completed a semistructured interview. Therapists were asked about their experiences of providing therapy to people who disclosed incestuous abuse that continued into adulthood and their experiences of training, peer support, and supervision in relation to these cases. The interviews were recorded, transcribed, labeled with a pseudonym, and deidentified. The transcripts were subjected to reflexive thematic analysis (TA) following the guidelines of Braun and Clarke (2006, 2022). The study found that three overarching themes described the therapeutic experience and response to this client group: (1) the therapist's emotional distress, vicarious traumatization, and moral injury at the extent of abuse and suffering disclosed by the client; (2) the need to adjust therapeutic goals and their reactions to this; and (3) feelings of professional isolation and a lack of support within mainstream services. The study describes therapeutic experience of a sample of practitioners and concludes that this work is distressing and demanding, requiring therapists to find their own coping methods, training, and supervision. The study points to needs for changes in practitioner training, service delivery, and policy to enable more holistic care of clients reporting complex ongoing abuse. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

The Prevalence of Domestic Verbal Abuse in Pregnant Women in a Semi-urban Area.

Introduction Domestic violence (DV) in the form of verbal abuse is very common amongwomen, especially pregnant women, posing as a serious public health issue that could lead to complications in pregnancy and threaten maternal and fetal outcomes. Studies have determined that domestic verbal abuse (DVA) in pregnancy was more common in women less than 25 years of ageas well as in those with low education levels. This study determined the overall prevalence of verbal abuse in pregnant women, in a semi-urban population and is unique in thatthe verbal abuse in pregnant women with a previous girl child was also determined. This study helps healthcare providers identify the potential causes of DVA in pregnancy and provide timely interventions in the form of counseling for pregnant women and families. Objective This observational study was carried out to assess the prevalence of DVA among pregnant women, to determine the trimester of occurrence of DVA among pregnant women, and to explore the associations of DVA with age, employment status, parity gestational age, and birth weight. Materials and methods This was a six-month hospital-based observational study conducted at Dr D. Y. Patil Medical College's in-patient department (IPD) of Obstetrics and Gynecology in Pimpri, Pune. Consent was obtained from 200 pregnant women who received admission for delivery and provided a validated modified copy of a DV assessment screening questionnaire. A statistical analysis was performed using GraphPad Prism 10. A Chi-square test was employed wherever required, and a p-value of less than 0.05 was considered significant. Results The study included 200 pregnant women, who were admitted to the hospitalfor delivery. The prevalence of DV in the form of verbal abusewas noted to be 74 out of 200 (37%). The working status of the woman showed an influence on DVA. There was also a significant increase in verbal abuse (68%) among the age group between 18 and 23 years. The previous delivery of a female child also had a significant impact on DVA, which turned out to be more prevalent, particularly if two female children were born previously (80%). The study also noted higher rates of preterm deliveries in pregnant women with DVA being 57%. Conclusion The study demonstrates that women, even in modern times, experience DVA during pregnancy, especially among the younger age group. It has also been found that it is more common among women who are financially dependent due to maternal unemployment. As a result, there is a need to routinely screen pregnant women for DVA to avoid potentially detrimental pregnancy outcomes and to prevent ongoing abuse.

Health Risks of Unaccompanied Immigrant Children in Federal Custody and in US Communities.

Unaccompanied immigrant children continue to arrive at the US-Mexico border and are at high risk for ongoing abuse, neglect, and poor mental and physical health. We are medical and legal experts in the fields of immigrant and refugee health, child abuse, and the legal rights of international refugee and migrant children. We provide an overview of US federal agencies with custody of unaccompanied immigrant children, a summary of medical care provided while in custody, and recent findings from the independent Juvenile Care Monitor Report mandating new custodial conditions for immigrant children while in federal custody. We provide recommendations to improve the health and well-being of unaccompanied immigrant children while in custody and once released to US sponsors. (Am J Public Health. 2024;114(3):340-346. https://doi.org/10.2105/AJPH.2023.307570).

Comparative Effects of Cognitive Rehabilitation and Photobiomodulation on Drug Craving in Treatment-Seeking Opioid Addicts.

Background: Drug addiction refers to a maladaptive pattern of drug use that frequently leads to substance abuse problems and accompanying cognitive and behavioral symptoms. Among the crucial criteria of drug addiction, craving stands out as a potent factor contributing to ongoing drug abuse and relapse following period of abstinence. To date, there is no definitive method for eradicating opioid cravings. The introduction of novel neurocognitive interventions, such as cognitive rehabilitation and photobiomodulation (PBM), into the realm of psychiatric treatments holds promise due to the parallels between drug addiction and other psychiatric disorders. These innovative techniques offer potential value in addressing drug addiction. Objective: This study aimed to assess and compare the efficacy of cognitive rehabilitation and PBM in alleviating drug cravings among individuals undergoing addiction treatment in clinical settings. Methods: The research used randomized clinical trial as the chosen research method. The statistical population encompassed all clients receiving treatment for addiction at clinics, selected through the convenience sampling method, with α = 0.05 significance level and an effect size of 85%. Gpower software was utilized to determine three equal groups. Sixty-three participants, each having a mean total score higher than 3 out of 5 on the Desire for Drug Questionnaire (DDQ), were randomly assigned to two experimental groups (n = 21 each) and a control group (n = 21). For the assessment of immediate and periodic opioid craving, the DDQ and the Obsessive Compulsive Drug Use Scale were used. In the low-level laser group, an 810 nm wavelength with continuous irradiation was applied twice a week at a distance of 1 cm by 1 cm to the prefrontal part of the brain for duration of 6 weeks (12 sessions). In the brain rehabilitation group, the stop signal and n-back tasks software were used twice a week for period of 6 weeks (comprising 12 sessions, each lasting 30 min). Results: The results demonstrated that each intervention significantly reduced drug craving in both the post-test and follow-up phases compared to the control group. The Bonferroni post hoc test indicated that PBM was more effective than cognitive rehabilitation in terms of working memory (WM) and inhibitory control for reducing drug craving (p < 0.05). Conclusions: While both PBM and cognitive rehabilitation targeting WM and inhibitory control effectively reduced opioid drug craving, low-level laser therapy proved to be more effective than cognitive rehabilitation in this regard.

Profiles of Victimized Outpatients with Severe Mental Illness in India.

Persons with severe mental illness (PwSMI) are at risk of being victimized due to persistent cognitive, emotional, and behavioral symptoms, which can become potential threats for effective reintegration into the community. A total of 217 PwSMI, receiving outpatient psychiatric treatment from a tertiary hospital, were screened for abuse, and if they were identified as abuse, then information about contextual factors contributing to abuse, sociodemographic, family, and clinical and legal profiles was created. Overall, 150 PwSMI were victimized, of which 56% were females, 50.7% were married, 20.7% were educated up to middle school, and 31.4% were homemaker. The most common form of diagnosis was schizophrenia (43.3%), with a mean duration of illness of 14 years. All the victimized PwSMI were subjected to emotional abuse. PwSMI were more likely to be victimized by multiple family members due to poor knowledge and understanding about illness (24%). The majority of the PwSMI had disclosed abuse (62.7%) to nonformal sources (33.3%) with no documentation in the clinical file (82.7%). PwSMI experience ongoing abuse and are more likely to be re-victimized, which increases the need for regular screening and culturally sensitive and comprehensive community-coordinated care and support.

Iron overload leading to cirrhosis in a patient with hereditary spherocytosis and heterozygosity for H63D mutation in the HFE gene

Hereditary spherocytosis (HS) refers to a group of autosomal dominantly inherited heterogeneous hereditary haemolytic anaemias (HHA). Significant iron overload in HS is uncommon. Iron overload has been described as a complication of HS when there is co-inheritance of hereditary haemochromatosis (HH). H63D mutation accounts for a minority of hereditary hemochromatosis cases and does not cause iron overload in an otherwise healthy heterozygous carrier state. We present a 64-year-old man , diagnosed with HS presenting with cirrhosis without significant on-going haemolysis. He had a markedly high serum ferritin and transferrin saturation. Magnetic Resonance Imaging for liver iron concentration revealed haemochromatosis of the liver. HFE genotyping showed heterozygosity for the H63D mutant allele. Haemolysis in HS does not usually result in clinically significant iron excess leading to haemochromatosis and the presence of H63D heterozygous mutation will increase the risk of clinically significant iron overload which can lead to hepatic iron deposition and fibrosis. Therefore, if a patient with H63D mutation demonstrates clinically significant iron overload, clinicians should search for other factors that increase iron excess such as on-going haemolysis, alcohol abuse and presence of metabolic syndrome.

Childhood Sexual Abuse and Relationship Satisfaction: The Moderating Role of PTSD and Sexual-Related Posttraumatic Stress Symptoms

Research on childhood sexual abuse (CSA) has consistently demonstrated the long-term effects of such abuse, not only on survivors’ development, but also on the nature and quality of their adult relationships, particularly romantic ones. In this study we examined the moderating role of posttraumatic stress disorder (PTSD) and sexual-related posttraumatic stress symptoms (sexual-related PTSS) between CSA and relationship satisfaction. Survey data from 529 individuals who reported being currently in a romantic relationship were analyzed. In the first set of analyses, results demonstrated that participants with CSA reported significantly lower relationship satisfaction and significantly greater severity of PTSD and sexual-related PTSS than participants without CSA. Sexual-related PTSS but not PTSD moderated the association between CSA and participants’ relationship satisfaction, with the model of sexual-related PTSS explaining 20.8% of the variance in relationship satisfaction and the model of PTSD explaining 11.3% of this variance. In the second set of analyses conducted among survivors of CSA only, higher sexual-related PTSS severity was linked with ongoing abuse and with abuse by a non-family member. This study points to the potential contribution made by sexual-related PTSS to relationship satisfaction among survivors of CSA.

The psychological impact on mothers who have experienced domestic violence when navigating the family court system: a scoping review

The aim of this scoping review was to synthesise the literature to identify what the psychological impacts of family court processes were on mothers who had experienced DFV. Twenty-five articles met inclusion criteria with four themes capturing the findings: Perpetrators using the system as a mode of coercive control; Secondary victimisation as a result of interacting with the system; Required to relive their abuse; and, Long-term psychological consequences of having engaged with the system. Key findings were that perpetrators manipulated the system to perpetrate further abuse and continue/reassert their control. Secondary re-victimisation was common, with poor knowledge of DFV and limited understanding of coercive control tactics and how these were employed by perpetrators by legal professionals identified as contributing factors. This review suggests that mothers who engage with the family court system experience a range of short- and long-term psychological impacts and court processes facilitate ongoing abuse by the perpetrator.

Get the word out: Monitoring human rights reduces abuse

Does human rights advocacy make a difference? Many are skeptical. Studies often find that advocates have an impact only under limited circumstances. I argue that these underwhelming results are a by-product of an identification problem. Research so far has effectively focused on whether shaming campaigns reduce ongoing abuse. But such cases are only part of the story. Another big aspect of advocacy is preventing abuse from ever starting. We must then pay attention to the deterred, those who chose not to violate human rights because of the threat of shaming. These cases do not repress and are never shamed. They are easy to miss because they look the same as those who never considered abuse in the first place. However, identifying deterred cases is crucial for judging the effectiveness of advocacy. I argue that we can resolve this issue by focusing on the degree of human rights monitoring in a country. Doing so allows researchers to recognize those under the scrutiny of advocates, and hence those that could have been deterred even if they were never shamed. Once we do this analytical refocus it is easy to see the positive effect of human rights advocacy. Human rights monitoring reduces abuse, and it does so in most countries.

Children's Theatre and Achieving Educational Goals in Schools

The most crucial aspects of community development، which connect to the future of each community's function and its future، are education and learning steps. In order for their correctness and stability to guarantee a good living for people and serve people، nations determine the fields of theater، education، and learning as well as the level of cultural and civil understanding that is to come. Children's theatrical development has always been at a low level in the Kurdistan Region due to ongoing occupation and abuses of sovereignty، and this weakness is increasingly apparent between 2003 and 2021. even while its justifications are altering. We will discuss the forerunners and goals of the development of children's theater since the Greek era as a source based on resources in this study. We will also analyze the essential elements of children's theatre and significant educational pathways، as well as different types of children's theatre and their effects on children، the circumstances of writing drama texts، the role، and responsibilities of the director's teacher in how to deal with performances and presentations، as well as s presenting some findings regarding children's theater and the impact of punctuality.

Associations between emotions and psychophysiological states and confirmation bias in question formulation in ongoing simulated investigative interviews of child sexual abuse.

In forensic settings interviewers are advised to ask as many open-ended questions as possible. However, even experts may have difficulty following this advice potentially negatively impacting an investigation. Here, we sought to investigate how emotions and psychophysiological parameters are associated with question formulation in real time in an ongoing (simulated) child sexual abuse (CSA) interview. In a experimental study, psychology students (N = 60, Mage = 22.75) conducted two interviews with child avatars, while their emotions (anger, sadness, disgust, surprise and relief), GSR and heart rate (HR) were registered. First, we found that general emotionality related to CSA and perceived realness of the avatars was associated with stronger overall emotional reactions. Second, we found that closed (vs. open) questions were preceded by more facially observable anger, but not disgust, sadness, surprise or relief. Third, closed (vs. open) questions were preceded by higher GSR resistance and lower heart rate. Results suggest for the first time that emotions and psychophysiological states can drive confirmation bias in question formulation in real time in CSA.

The Clothes Maketh the Cult

The Clothes Maketh the Cult

Beyond the Boundaries of Childhood: African American Children in the Antebellum North

Beyond the Boundaries of Childhood: African American Children in the Antebellum North

Survivors “Surviving Well” and “Surviving Poorly”: Reflections on the Limitations and Possibilities of Transformative Justice

Survivors “Surviving Well” and “Surviving Poorly”: Reflections on the Limitations and Possibilities of Transformative Justice

Multi-Layered Civil Society Documentation of Human Rights Violations in Myanmar: The Potential for Accountability and Truth-Telling

AbstractSerious human rights violations, particularly against ethnic minorities, have been a stark reality in Myanmar for many decades. The Rohingya crisis that deteriorated in 2017 and the ongoing abuses in areas of armed conflict such as Kachin, Rakhine, and Shan States, and more recently in response to anti-coup protests, demonstrate the recurrence of violence and trauma. During these decades of violence and ongoing violations, civil society initiatives inside and outside the country have attempted to monitor and document human rights abuses in order to contribute towards accountability and truth-telling. Despite the vast array of civil society documentation efforts, this work has sparked limited scholarly debate, especially concerning the complexities of existing multi-layered systems of documentation. This article analyses the current scope of documentation work related to serious human rights violations in Myanmar and the methods, standards, and audiences of various initiatives. We distinguish three layers of civil society documentation: (i) initiatives carried out on the local level in Myanmar and the various border areas; (ii) initiatives carried out by the refugee and diaspora communities; and (iii) third-party initiatives. We then analyse two elements that complicate documentation efforts, namely the risk of ‘over-documentation’, and issues of hierarchy and contestation. These challenges make clear the value of strengthening partnerships and cooperation for all groups involved in documentation work that aims to promote and protect human rights. We end by cautiously considering the potential impact, value, and limitations of Myanmar’s multi-layered documentation efforts for accountability and truth-telling in the aftermath of the 2021 military coup.

Use of Mandibular Distraction Osteogenesis to Correct Micrognathia and Airway Obstruction in Newborn Female with Pierre Robin Sequence and Neonatal Abstinence Syndrome in Rural Appalachia

We present a case of Pierre Robin sequence and Neonatal Abstinence Syndrome (NAS) in a newborn female patient to highlight the surgical technique of mandibular distraction osteogenesis to correct airway obstruction due to micrognathia. The patient presented as a transport after delivery due to respiratory distress. She was noted to have a cleft palate and micrognathia. The absence of other dysmorphic features diagnosed her with non-syndromic Pierre Robin sequence. To solve her upper airway obstruction, mandibular distraction osteogenesis was performed. This procedure allowed the patient to be weaned from all respiratory support and nasogastric tube feeds by the end of her hospitalization. She was able to be discharged home weeks before her internal hardware was surgically removed. Mandibular distraction osteogenesis was previously unavailable in rural Appalachia, making this case novel to the area. The patient also developed NAS during her hospitalization, highlighting the ongoing substance abuse epidemic in Appalachia.

Clinical question: How to manage symptoms of hypogonadism in patients after androgen abuse?

Androgen abuse is relatively common amongst young (amateur) bodybuilders. After cessation, the hypothalamic-pituitary-gonadal (HPG) axis-which has been suppressed by the androgens-needs time to recover. The endogenous testosterone production often recovers within 3 months, however, prolonged or permanent post-androgen abuse hypogonadism (PPAAH) has been described. There is no widely accepted definition nor is its pathogenesis completely elucidated. To date it is a subject of debate whether PPAAH is a separate entity, reflecting irreversible damage to essential components of the HPG axis inflicted by long-term exposure to high doses of androgens. Alternately, it may be the result of longer than expected suppressive effects of androgen depots, undisclosed ongoing androgen abuse or undiagnosed unrelated disorders. Due to the lack of scientific evidence, the management of PPAAH is challenging. By combining clinical experience with evidence from the recent literature, a suggested outline of the management of androgen-abuse-induced hypogonadism are given.

Factors affecting frequency of child maltreatment in South Korea

AbstractA substantial proportion of children suffer multiple episodes of maltreatment over a prolonged period. The cumulative risk of maltreatment is critical to understanding both the nature and effects of victimisation. However, limited studies have investigated the frequency of child maltreatment and the factors influencing its recurrence. This study explored detailed characteristics of non‐sexual child maltreatment in South Korea and determined the factors predicting multiple incidents of child maltreatment using data from investigation and trial records of child maltreatment‐related cases from 2010 to 2015. Based on 440 such cases, the authors examined the characteristics of victims and perpetrators and the features of maltreatment employing the ordered logit model analysis. Child maltreatment was more frequent among children living with the perpetrator and those living with stepparents. The higher the age of the victim, the more frequent the maltreatment. Child maltreatment was also more frequent when the offender was a female. Among the types of maltreatment, emotional abuse and neglect were the most frequent forms of child maltreatment. By identifying various factors influencing the frequency of child maltreatment, the findings can contribute towards protecting children from ongoing maltreatment.Key Practitioner Messages Practitioners need to understand where and how child maltreatment is occurring, so that they may introduce effective interventions. The frequency of child maltreatment rose significantly when the victims lived with a stepparent and when the case involved emotional abuse and neglect. It is imperative to prevent damage to children from ongoing emotional abuse and neglect, especially since it is mostly overlooked compared to physical abuse.

A Political Agenda in Conflict with Environmental Protection: A Critical Policy Essay from Brazil

Current Brazilian policies on environmental protection have become a worldwide concern since President Bolsonaro’s election in 2018. Not only have his speeches been aggressive and critical of environmental protections, but many of his actual decisions have shown a very dangerous negligence of populations and interests affected by environmental harms. As a consequence, different environmental crises have plagued the country without any adequate response by public agencies or emergency plans to diminished harms. This essay uses a regulatory approach to demonstrate how the recent large withdrawal of environmental protection instruments in Brazil have supported a harmful and unlawful political agenda. First, we reconstruct the historical narrative of Brazilian environmental policy between the years 2018 and 2021, demonstrating through journalistic reports and social organizations’ alerts, how the speeches, actions and omissions of the Brazilian government may have contributed to the present environmental situation. Using an environmental justice perspective, we demonstrate a lack of legitimate influence on political decisions related to environmental protection. Subsequently, we discuss the existing legal instruments to respond to the political abuses in the Brazilian legal system, in order to demonstrate their insufficiency to deal with this scenario. Finally, we evaluate international criminal law as a possible answer to the ongoing environmental abuses in Brazil.