Developments in computer communications and networks enabled the deployment of exciting new areas. Meanwhile, Efficient network and communication technologies also promote the development of routing protocols. AODV(Ad hoc On-Demand Distance Vector Routing, AODV) routing protocol has invulnerability to different mobile attributes of agent nodes and network damage scenarios. However, this invulnerability performance can not meet the needs of mobile multi-agent cooperative communication. Therefore, this paper proposes an improved responsive multipath routing protocol MD_AODV(Multipath Destroy-resistance AODV, MD_AODV). This routing protocol is based on AODV routing protocol. It is mainly improved in three aspects: multichannel concurrency mechanism, node load balancing mechanism and shortest path maintenance mechanism. Firstly, in this research, an improved multipath routing protocol is modeled and implemented, which is based on OPNET Network simulation platform. Then, network models with different degrees of impairment are built. Combines the mobile attributes of mobile multi-agent task coordination to carry out invulnerability simulation experiments . These experiments study the invulnerability of the improved multipath routing protocol. Finally, this paper evaluates and compares the routing invulnerability of MD_AODV, AODV and AOMDV(Ad-hoc On-Demand Multipath Distance Vector, AOMDV). The evaluation results show that MD_AODV routing has better invulnerability when the network is severely damaged