Aims: To assess the healthcare products and cleaning solutions used in neonatology units throughout France and to evaluate the main determinants of the newborn's nosocomial olfactory environment. Methods: An electronic questionnaire was sent to 99 neonatal units in France. Senior nurses and/or physicians described the nature and use of skincare products (e.g., umbilical cord and skin care products, skin disinfectants, adhesive removers), lubrications used for tube positioning, and disinfectants used to clean materials such as incubators or ultrasound probes, hand hygiene products (e.g., alcohol-based hand rubs, antimicrobial and plain soaps), and newborns' bath. Results: We achieved a 49.5% (i.e., 49 of 99) response rate. Nine groups of products and 76 distinct commercial preparations were identified. Depending on their vulnerability, newborns infants were estimated to be exposed to nosocomial odours an average of 48 to 64 times daily, although higher levels were reported by some respondents. Use of the products varied among the medical centres. Newborns were most frequently exposed to the odour of hand hygiene products (aqueous alcoholic solutions, soaps) and skin antisepsis products. Conclusions: This survey reveals that newborns are exposed to high levels of olfactory and trigeminal stimuli of nosocomial origin, thereby increasing the complexity of the newborn's olfactory environment. The impact of these stimuli on the short-term wellbeing and long-term development of newborns should be systematically evaluated. Although most of these products are necessary, a wise use of them is recommended. Consensus guidelines should be developed and promoted to regulate their use.