Objective. Reviewing oil palm fibre (OPF) utilisation in various medical sectors. Background. The OPF, especially in nanocellulose form, is frequently used due to its exceptional mechanical attributes, considerable surface area, versatility for surface functionalisation, biocompatibility, and nontoxicity. Method. Only articles published in the last ten years (2012-2022) and written in English were reviewed in this study. An electronic search was conducted in Google Scholar, ScienceDirect, and PubMed using the terms “oil palm fibres in the medical field” and “oil palm fibre.” Results. Among the 459 articles obtained, only 24 were accessible as full text and satisfied the parameters set in this study. Conclusion. The OPF could be widely employed in the medical domain, particularly the biomedical branch, for drug delivery, tissue engineering, wound dressing, and antimicrobial agent transporters. The substance also demonstrated promising results and significant capacities to be utilised and further studied.