The fluid domain model of a new oil-air distributor in oil-air lubrication system is built and the phase distribution of oil and air two-phase flow on distribution interface is simulated based on the CFD model in Fluent, the mass flow rate of oil and air are collected from three different cross sections when the structures of oil-air guidance slot are designed as a plane, sphere and cone shape respectively, then the influence of oil-air guidance slot structure on the performance of distributor is analyzed in the oil-air lubrication system in this paper. The results show that the spherical surface and conical surface of oil-air guidance slot can improve the uniformity and stability of the oil and air two-phase flow distribution, promote the flow pattern to form a continuous annular oil film. Among these three structures of oil-air guidance slot, we also find that the distribution performance of conical surface is the best.