Abstract Background The vast majority of esophageal tumors are cancer. Benign esophageal tumors constitute less than 1% of all esophageal tumors. Approximately 80% of benign esophagus tumors are leiomyomas. This study aims to evaluate outcomes of thoracoscopic management of esophageal leiomyomas. Methods Between January 2010 and December 2017, eleven cases (5 females, 6 males; mean age 45 years; range 30 to 59 years) who were operated with thoracoscopic resection due to esophageal leiomyoma were retrospectively analyzed. Age and sex of the patients, symptoms, localization of lesions, diagnosis, surgical modality, length of hospital stay and morbidity and mortality rates were reviewed. All cases were preoperatively examined using direct chest radiography, computed tomography (CT), and esophagoscopies, with endoscopic ultrasonography (EUS) also being employed in seven cases. Results Five patients had dysphagia and four patients were asymptomatic. Leiomyoma was located in 1/3 of the middle esophagus in all cases. All patients underwent right thoracoscopic enucleation (Single port incision in three cases). Leiomyoma was a solitary lesion in all cases. After the enucleation, 0.9% NaCl was inserted into the posterior mediastinal region. Nasogastric tube was inflated to check for leakage. Except for two cases, in all cases, the esophageal muscle layer was closed as an absorbable suture. The mean diameter of leiomyoma was 5.1 cm (range, 2 to 9 cm). Postoperative mortality was not observed in any of the cases. Postoperative pseudodiverticulum occurred in one of the cases. The mean length of hospital stay was 5.8 days (range, 4 to 11 days). Conclusion In esophageal leiomyomas, surgery provides both definitive diagnosis and treatment. Thoracoscopic enucleation in esophageal leiomyomas is an effective and safe treatment method. Disclosure All authors have declared no conflicts of interest.