AbstractThe purpose is to report a case series of increasing prevalence of ocular Dirofilariasis in tropical areas of South India and the importance of the disease with travel to tropical areas Human Dirofilariasis, caused by Dirofilaria repens, have been reported to occur widely throughout Asia, Europe, and Africa. The Dirofilaria are natural parasites of mammals and are transmitted to man by zooanthrophilic mosquitoes. It is emphasized that both clinicians and microbiologists should have an increased awareness of this entity and include dirofilariasis in the differential diagnosis of patients presenting with subcutaneous nodules. Excision of the lesion is both diagnostic and therapeutic.