To the Editor.— Although Serratia organisms were formerly considered nonpathogenic, they are now recognized as potential pathogens. 1,2 Several instances of Serratia osteomyelitis, 1,3,4 have been reported. The present account describes the occurrence of osteomyelitis due to Ser ratia organisms in a patient with sickle cell disease. Report of a Case.— A 20-year-old Negro college student was admitted to the Milwaukee County General Hospital because of persistent pain in the left thigh and fever. Three months previously he had been admitted to another hospital for complaints of pain in the left thigh and back thought to be secondary to a sickle cell crisis. One month previously he was readmitted to the same hospital for persistent pain in the left thigh. Again this was thought to be related to sickle cell crisis. He had been treated with analgesics, intravenous fluids, and two units of packed red blood cells. At no time