Background and objective Many cities in the world have land subsidence problems because of environmental issues related to urban development. The arid and semi-arid climatic conditions prevailing in most of the interior regions of Iran and the need for the increasing industrial, agricultural, and drinking water exploitation from underground water resources, as well as urban development, have increased the occurrence of land subsidence in Iran, especially in the metropolis of Tehran. This study aims to assess land subsidence in Tehran, Iran, using the satellite radar interferometry (InSAR) technique. Method In this research, 31 images of Sentinel-1 were processed using the time series of persistent scatter interferometry (PSI) in 2022, and a map of the average annual rate of land subsidence in Tehran metropolis was prepared. Finally, after validating the results of interferometry with GPS station observations, the relationship between land subsidence and exploitation of underground water resources was examined as the most important factor in ground surface changes in the study area. Results The findings showed a decreasing trend in land subsidence from plain to urban areas. The highest land subsidence, with a rate of -43 mm per year occurred in the southern and southwestern parts of Tehran. Districts 10, 11, 12, 16, 17, 18, 19, and 20, which comprise about 26% of Tehran’s population, were experiencing land subsidence. The drop in the water level of observation wells was considerable in the areas where the highest rate of land subsidence occurred. Another finding of the research was the decrease of the underground water level from the north to the south of Tehran, indicating that the water depth in the southern areas of Tehran decreased due to human activities such as water pumping. Conclusion There is an increasing pressure in the aquifer through pumping water from wells in the study area for various industrial, agricultural and drinking water uses which has led to the increase in the occurrence of land subsidence.