The aim of this work is improving the procedure for professional risk assessment of passenger bus drivers, taking into account ergonomic, psychosocial, individual, and hygienic factors.
 To develop the methodology for assessing the professional risk of drivers the theory of analysis was used, which allows to establish alternative solutions of the problem by determining an integrated criterion that depends on a number of individual indicators characterized by ergonomic, psychosocial, individual, and hygienic factors influencing the working conditions of the passenger bus driver.
 A checklist has been developed to quickly assess the occupational risk of passenger bus drivers, which takes into account the impact of several harmful production factors that contribute to the creation of unfavorable conditions for the occurrence of occupational diseases. A feature of this approach is the ability to distinguish the level of risk for each harmful production factor and determine the overall level of occupational risk. It is recommended to reduce the effect of occupational risk on the driver of a passenger bus to improve the system of medical examinations, the system of admission to the vehicles driving in the implementation of passenger traffic and strengthen control over the technical condition of vehicles.
 The relationship between the integrated criterion of occupational risk of the driver and indicators that are characterized by ergonomic, psychosocial, individual, and hygienic factors, which are formed by the working conditions of the driver in the carriage of passengers.
 As a result, a new approach (checklist) is proposed, which can be used in trucking companies without any additional equipment after training in testing.
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