The medical condition of the higher-education teaching personnel of the university is reflected in the quality of the educational process in the educational institution and, as a consequence, in the formation of professional competencies of future graduates. It is known that workers in the fields of education and health care more than others are subject to stress, physical inactivity and, as a result, professional (emotional) burnout. The present study is devoted to the study of the state of health, activity, mood, professional (emotional) burnout of the teaching staff of a medical university, assessment of the intensity of their work process, professional risk. The study of well-being, activity, mood, professional (emotional) burnout was carried out using a questionnaire survey using well-known methods. The assessment of the intensity of the labor process was carried out in accordance with the Guidelines for the assessment of occupational health risks for workers. The assessment of occupational risk categories was carried out in accordance with the Guidelines for Assessing Occupational Risk for Workers' Health, as well as using a matrix of consequences and probabilities according to GOST Risk Management. Risk assessment technologies. It was found that the working conditions of the teaching staff of a medical university are tense 2 degrees. Evaluation of the functional emotional state showed that the teaching staff of a medical university has moderate emotional burnout, against the background of a high level of psychoemotional exhaustion. Indicators of well-being and mood have high (favorable) levels, while the activity indicator, on the contrary, has a low (unfavorable) value, presumably against the background of increasing employee fatigue. The occupational health risk of employees is medium (significant), the risk class according to the severity of the possible consequences of identified hazardous events is medium (T3), the probability of the consequences of a hazardous event is high (B4), the risk class is medium (C12).