Indonesia is one of the contributing countries of the highest accidents. Recorded in 2016 has occurred 101,367 cases of work accidents with the death toll reached 2,363 inhabitants. Implementation of OSH in Indonesia is very rarely heard in educational institutions such as schools and universities. Though the university is a place of many human activities. Various activities that occur on campus such as lecture room, park, library, laboratory, parking area, and canteen. The place can trigger the emergence of many dangers and disasters, the risks of occupational injuries and occupational diseases that can cause casualties to lecturers, students, employees, and visiting guests. Based on the background of the problems that have been described, it is necessary to review how the government of Indonesia in improving the program of occupational safety and health, how the general description of the implementation of occupational safety and health programs at UGM, and how knowledge and attitude of occupational safety and health by UGM students. This research use case study method and literature study. Primary data: obtained from direct observation and interview. Secondary Data: online media review literature. The results showed that the government of Indonesia has made efforts to improve OSH programs as the development of OSH program in 2016, although the number of work accidents in Indonesia is still high, the Indonesian government succeeded in reducing the number of accidents by more than half that occurred from 359,724 accidents in 2015 decreased to 101,367 in 2016. In addition, OSH culture in Indonesia is not only focused on industry but also has been done to improve the OSH culture in all parts of the government, universities and related education institutions, professional organizations, associations, company leaders, workers, and other communities, to make concrete efforts on the implementation of OSH in their respective environments. Implementation of Occupational Health at Universitas Gadjah Mada shows that from 17 criteria that have been made 14 criteria have been fulfilled (82,35%) and 3 Criteria not fulfilled (17,64%) this shows that implementation of health work at Universitas Gadjah Mada is good. Based on the results of observations of the implementation of Safety indicates that of the 13 criteria that have been made, 10 criteria have been met (76.92%) and 3 criteria not fulfilled (23.07%). This shows that the application of safety at Universitas Gadjah Mada is good. Although the implementation of Occupational Safety and Health at UGM has been good but still needs improvement from several aspects in order to achieve satisfactory criteria. Knowledge and Attitudes of Occupational Safety and Health by UGM students are still less visible from the lack of understanding related to catching disaster emergency, accident risk control and risk of occupational diseases and non-compliance to the use of PPE, due to the absence of training, socialization and supervision related Occupational safety and health at universities especially for students. In conclusion, with efforts to improve OSH program in Indonesia succeeded in reducing the number of accidents to reach a half, the implementation of OSH at UGM has been running well but need to increase socialization and training for the OSH culture in the students.