Introduction. Discrepancies in the regulatory documents regulating the compilation of sanitary and hygienic characteristics (SGC) of pilots' working conditions, the lack of a complex of laboratory and instrumental studies conducted at the workplace and, as a result, incomplete and unreliable compilation of SGC, lead to difficulties in establishing the connection between the disease and the pilot's profession. The aim of study is to conduct a critical analysis of the quality of the preparation of the CGS, followed by identifying the main violations of the requirements of regulatory documents in the design of the CGS. Materials and methods. A retrospective analysis of the quality of registration of the SGC of pilots with an established diagnosis of occupational disease was performed. Results. Contradictions in the current legal acts are established and discrepancies in methods for assessing the normalized indicators of working conditions of pilots are revealed. The data obtained indicate that the main requirements for filling out the SGC, justified by the specifics of the working conditions of pilots, are not taken into account when they are issued; when evaluating the measurement results, non-current regulatory documents are used, or documents that do not regulate the working conditions of civil aviation pilots. Conclusions. To improve the quality of registration of the SGC, it is necessary to update the current regulations and develop guidelines with the establishment of the form of the SGC for working conditions of civil aviation flight personnel in case of suspected occupational disease.