Incorporating daylight inside occupied spaces has several benefits, including reduced lighting load, improved mental and physical health of occupants, and increased productivity during working hours. Several Innovative daylighting systems that utilize advanced technologies and design approaches are devised and tested to bring natural light into occupied spaces. Amongst them, the Tubular Daylighting Devices (TDD) have immense potential to trap the sunlight and carry it to enclosed/dimly lit areas, especially in tropical climates.The careful selection of system components dictates TDD's spatial and temporal illumination performance. The present study aims to analyze and correlate the performance of various TDD systems with different collector-diffuser configurations widely reported in the literature and used commercially. The study uses the Daily Useful Daylight Illuminance (DUDI) paradigm and uniformity criterion to assess the performance of carefully chosen collectors, namely, hemispherical dome, prismatic dome, and faceted collector, with the selected diffusers: flat plate acrylic, hemispherical dome, flat prismatic, and flat Fresnel lens. The study encompasses the identification, modeling, and simulation of different configurations throughout the year at four chosen cities in India. Results indicate that the maximum and average lighting level measured is high in the case of the hemispherical collector when paired with flat diffusers at all seasons and cities considered for the study. A matrix of different configurations of system components is tabulated for each location based on a predefined criterion. The increase in diameter of the tube improved the lighting level above 150 lx even at a distance of 1.5 m from the center, and splitting the light pipe into two pipes of an equivalent cross-sectional area improved the end illumination levels at the periphery of the room (10–25 %) making it better in terms of both illuminance and uniformity when paired with hemispherical/faceted collector and flat diffuser.